Question 1

Which of these agents do not inhibit bacterial cell-wall synthesis?

Accepted Answer

A) Vancomycin 
B) Erythromycin 
C) Penicillin G 
D) Cefazolin 
A) Vancomycin 
B) Erythromycin 
C) Penicillin G 
D) Cefazolin

Question 2

The standard antibiotic drug regimen prior to dental procedures requiring immunoprophylaxis in a patient with no allergies to penicillin or amoxicillin is _____ g of amoxicillin _____ hour(s)before the procedure.

Accepted Answer

A) 1;1 
B) 1;2 
C) 2;1 
D) 2;2 
A) 1;1 
B) 1;2 
C) 2;1 
D) 2;2

Question 3

Which of the following antibiotics is associated with photosensitivity?

Accepted Answer

A) Erythromycin 
B) Tetracycline 
C) Metronidazole 
D) Aminoglycosides (e.g. ,streptomycin) 
A) Erythromycin 
B) Tetracycline 
C) Metronidazole 
D) Aminoglycosides (e.g. ,streptomycin)

Question 4

_____ can cause black pigmentation of mandibular and maxillary alveolar bone and the hard palate.

Accepted Answer

A) Penicillin V 
B) Erythromycin 
C) Minocycline 
D) Clindamycin 
A) Penicillin V 
B) Erythromycin 
C) Minocycline 
D) Clindamycin

Question 5

Which of the following statements is true concerning antibiotic resistance?

Accepted Answer

A) Natural resistance occurs when an organism that was previously sensitive to an antimicrobial agent develops resistance. 
B) An increase in the use of an antibiotic in a given population decreases the proportion of resistant organisms in that population. 
C) Bacterial resistance can occur by the transfer of deoxyribonucleic acid (DN
A) genetic material from one organism to another. 
D) The transfer of genetic material from one organism to another may only occur among organism of the same species. 
A) Natural resistance occurs when an organism that was previously sensitive to an antimicrobial agent develops resistance. 
B) An increase in the use of an antibiotic in a given population decreases the proportion of resistant organisms in that population. 
C) Bacterial resistance can occur by the transfer of deoxyribonucleic acid (DN
A) genetic material from one organism to another. 
D) The transfer of genetic material from one organism to another may only occur among organism of the same species.

Question 6

The usual adult dose of penicillin V for treatment of an infection is

Accepted Answer

A) 250 mg twice a day (bid). 
B) 250 mg four times a day (qid). 
C) 250 to 500 mg twice a day (bid). 
D) 250 to 500 mg four times a day (qid). 
A) 250 mg twice a day (bid). 
B) 250 mg four times a day (qid). 
C) 250 to 500 mg twice a day (bid). 
D) 250 to 500 mg four times a day (qid).

Question 7

Which antibiotic is useful in the treatment of many anaerobic periodontal infections?

Accepted Answer

A) Metronidazole 
B) Penicillin VK 
C) Erythromycin 
D) Azithromycin 
A) Metronidazole 
B) Penicillin VK 
C) Erythromycin 
D) Azithromycin

Question 8

The possibility of superinfection can be minimized by use of the _____ specific antiinfective agent,the _____ effective course of therapy,and adequate doses.

Accepted Answer

A) least;shortest 
B) least;longest 
C) most;shortest 
D) most;longest 
A) least;shortest 
B) least;longest 
C) most;shortest 
D) most;longest

Question 9

Azithromycin and clarithromycin

Accepted Answer

A) cause lysis of the bacterial cell wall. 
B) are not effective against anaerobes. 
C) have a higher incidence of adverse reactions than erythromycin. 
D) may be used as alternative antibiotics for the prophylaxis of endocarditis and prosthetic joint infections. 
A) cause lysis of the bacterial cell wall. 
B) are not effective against anaerobes. 
C) have a higher incidence of adverse reactions than erythromycin. 
D) may be used as alternative antibiotics for the prophylaxis of endocarditis and prosthetic joint infections.

Question 10

If an infection is just beginning,the organisms most likely to be present are

Accepted Answer

A) gram-positive cocci. 
B) gram-negative cocci. 
C) gram-positive anaerobes. 
D) gram-negative anaerobes. 
A) gram-positive cocci. 
B) gram-negative cocci. 
C) gram-positive anaerobes. 
D) gram-negative anaerobes.

Question 11

Quinolones

Accepted Answer

A) must be administered parenterally and cannot be taken orally. 
B) have no use in dentistry. 
C) are bactericidal against most gram-negative organisms and many gram-positive organisms. 
D) have cross-resistance with many other antimicrobial agents. 
A) must be administered parenterally and cannot be taken orally. 
B) have no use in dentistry. 
C) are bactericidal against most gram-negative organisms and many gram-positive organisms. 
D) have cross-resistance with many other antimicrobial agents.

Question 12

The sulfonamides competitively inhibit the bacterial enzyme that incorporates para-aminobenzoic acid (PABA)into an immediate precursor of

Accepted Answer

A) biotin. 
B) thiamine. 
C) folic acid. 
D) riboflavin. 
A) biotin. 
B) thiamine. 
C) folic acid. 
D) riboflavin.

Question 13

Which of the following salts of penicillin G produces the most rapid and highest blood level?

Accepted Answer

A) Potassium salt given intravenously 
B) Potassium salt given intramuscularly 
C) Benzathine salt given intramuscularly 
D) Procaine salt intramuscularly 
A) Potassium salt given intravenously 
B) Potassium salt given intramuscularly 
C) Benzathine salt given intramuscularly 
D) Procaine salt intramuscularly

Question 14

Which is a penicillinase-resistant penicillin?

Accepted Answer

A) Ampicillin 
B) Amoxicillin 
C) Cloxacillin 
D) Ticarcillin 
E) Piperacillin 
A) Ampicillin 
B) Amoxicillin 
C) Cloxacillin 
D) Ticarcillin 
E) Piperacillin

Question 15

Which of the following combinations of three drugs are administered concurrently in active cases of pulmonary tuberculosis (TB)?

Accepted Answer

A) Pyrazinamide (PZ
A) ,rifapentine,and Rifater 
B) Isoniazid (INH),rifampin,and pyrazinamide 
C) Ethambutol,isoniazid (INH),and Rifater 
D) Rifampin,PZA,and streptomycin 
A) Pyrazinamide (PZ
A) ,rifapentine,and Rifater 
B) Isoniazid (INH),rifampin,and pyrazinamide 
C) Ethambutol,isoniazid (INH),and Rifater 
D) Rifampin,PZA,and streptomycin

Question 16

Which antibiotic is utilized particularly due to effectiveness against anaerobic bacteria?

Accepted Answer

A) Penicillin 
B) Erythromycin 
C) Metronidazole 
D) Clindamycin 
E) Tetracycline 
A) Penicillin 
B) Erythromycin 
C) Metronidazole 
D) Clindamycin 
E) Tetracycline

Question 17

Which of the following agents is the drug of choice for an early dental infection unless the patient is allergic to it?

Accepted Answer

A) Erythromycin 
B) Clindamycin 
C) Penicillin 
D) Metronidazole 
A) Erythromycin 
B) Clindamycin 
C) Penicillin 
D) Metronidazole

Question 18

The misuse of antibiotics has contributed to antibiotic resistance.The solution to reducing the incidence of antibiotic-resistant bacteria is to write more prescriptions for antibiotics.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true.

Question 19

Administration of metronidazole for dental infections during pregnancy is

Accepted Answer

A) contraindicated. 
B) permitted only during the second trimester. 
C) permitted during the last half of pregnancy. 
D) permitted without restriction. 
A) contraindicated. 
B) permitted only during the second trimester. 
C) permitted during the last half of pregnancy. 
D) permitted without restriction.

Question 20

Antiinfective agents can potentiate the effect of oral anticoagulants by interfering with the production of vitamin

Accepted Answer

A) A. 
B) D. 
C) E. 
D) K. 
A) A. 
B) D. 
C) E. 
D) K.

Exam 7: Antiinfective Agents

Which of these agents do not inhibit bacterial cell-wall synthesis?

The standard antibiotic drug regimen prior to dental procedures requiring immunoprophylaxis in a patient with no allergies to penicillin or amoxicillin is _____ g of amoxicillin _____ hour(s)before the procedure.

Which of the following antibiotics is associated with photosensitivity?

_____ can cause black pigmentation of mandibular and maxillary alveolar bone and the hard palate.

Which of the following statements is true concerning antibiotic resistance?

The usual adult dose of penicillin V for treatment of an infection is

Which antibiotic is useful in the treatment of many anaerobic periodontal infections?

The possibility of superinfection can be minimized by use of the _____ specific antiinfective agent,the _____ effective course of therapy,and adequate doses.

Azithromycin and clarithromycin

If an infection is just beginning,the organisms most likely to be present are

Quinolones

The sulfonamides competitively inhibit the bacterial enzyme that incorporates para-aminobenzoic acid (PABA)into an immediate precursor of

Which of the following salts of penicillin G produces the most rapid and highest blood level?

Which is a penicillinase-resistant penicillin?

Which of the following combinations of three drugs are administered concurrently in active cases of pulmonary tuberculosis (TB)?

Which antibiotic is utilized particularly due to effectiveness against anaerobic bacteria?

Which of the following agents is the drug of choice for an early dental infection unless the patient is allergic to it?

The misuse of antibiotics has contributed to antibiotic resistance.The solution to reducing the incidence of antibiotic-resistant bacteria is to write more prescriptions for antibiotics.

Administration of metronidazole for dental infections during pregnancy is

Antiinfective agents can potentiate the effect of oral anticoagulants by interfering with the production of vitamin

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The standard antibiotic drug regimen prior to dental procedures requiring immunoprophylaxis in a patient with no allergies to penicillin or amoxicillin is _ g of amoxicillin _ hour(s)before the procedure.

The possibility of superinfection can be minimized by use of the _ specific antiinfective agent,the _ effective course of therapy,and adequate doses.