Question 1

Which of the following is the first choice of therapy for most patients with atherosclerotic heart disease and elevated cholesterol levels?

Accepted Answer

A) Fenofibrate 
B) Niacin 
C) Colestipol (Colesevelam) 
D) Omega-3 fish oil 
E) 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor 
A) Fenofibrate 
B) Niacin 
C) Colestipol (Colesevelam) 
D) Omega-3 fish oil 
E) 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

Question 2

Statins are contraindicated as an antihyperlipidemic therapy in pregnant women.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following groups of diuretics are called the "puny" diuretics?

Accepted Answer

A) Thiazide 
B) Loop 
C) Potassium-sparing 
D) Both A and B 
E) Both B and C 
A) Thiazide 
B) Loop 
C) Potassium-sparing 
D) Both A and B 
E) Both B and C

Question 4

Which of the following statement is true concerning the use of b-adrenergic blocking agents for the treatment of angina pectoris?

Accepted Answer

A) These drugs block the g response to catecholamine stimulation,thereby reducing both the chronotropic and inotropic effects. 
B) b-adrenergic blockers are effective in reducing exercise but not stress-induced anginal episodes. 
C) Adverse effects of b-adrenergic blocking agents include tachycardia,headache,and excessive salivation. 
D) The net result of the use of b-adrenergic blocking agents for the treatment of angina pectoris is a reduced myocardial oxygen demand. 
A) These drugs block the g response to catecholamine stimulation,thereby reducing both the chronotropic and inotropic effects. 
B) b-adrenergic blockers are effective in reducing exercise but not stress-induced anginal episodes. 
C) Adverse effects of b-adrenergic blocking agents include tachycardia,headache,and excessive salivation. 
D) The net result of the use of b-adrenergic blocking agents for the treatment of angina pectoris is a reduced myocardial oxygen demand.

Question 5

Which of the following antibiotics can increase the toxicity of digoxin in some patients? (Select all that apply. )

Accepted Answer

A) Penicillin 
B) Erythromycin 
C) Tetracycline 
D) Metronidazole 
E) Ampicillin 
A) Penicillin 
B) Erythromycin 
C) Tetracycline 
D) Metronidazole 
E) Ampicillin

Question 6

Which antihypertensive agent is associated with a nonproductive cough?

Accepted Answer

A) angiotensin receptor blocker 
B) beta-adrenergic blocking agent 
C) alphA₁-adrenergic blocking agent 
D) angiotensin-converting enzyme inhibitor 
A) angiotensin receptor blocker 
B) beta-adrenergic blocking agent 
C) alphA₁-adrenergic blocking agent 
D) angiotensin-converting enzyme inhibitor

Question 7

The therapeutic target international normalized ratio (INR)for most indications,such as thrombophlebitis,is

Accepted Answer

A) less than 1. 
B) between 2 and 3. 
C) between 3.5 and 4.5. 
D) over 4.5. 
A) less than 1. 
B) between 2 and 3. 
C) between 3.5 and 4.5. 
D) over 4.5.

Question 8

Many _____ end in the suffix -pril.

Accepted Answer

A) b-adrenergic blockers 
B) calcium channel blockers 
C) angiotensin-converting enzyme inhibitors (ACEIs) 
D) angiotensin receptor blockers (ARBs) 
A) b-adrenergic blockers 
B) calcium channel blockers 
C) angiotensin-converting enzyme inhibitors (ACEIs) 
D) angiotensin receptor blockers (ARBs)

Question 9

Essential hypertension is

Accepted Answer

A) of unknown cause. 
B) iatrogenic hypertension. 
C) precipitated by another disorder. 
D) a rapidly developing form of hypertension,requiring aggressive therapy. 
A) of unknown cause. 
B) iatrogenic hypertension. 
C) precipitated by another disorder. 
D) a rapidly developing form of hypertension,requiring aggressive therapy.

Question 10

A serious lupus-like reaction is associated with which cardiovascular drug?

Accepted Answer

A) Clonidine 
B) Hydralazine 
C) Isosorbide dinitrate 
D) Spironolactone 
A) Clonidine 
B) Hydralazine 
C) Isosorbide dinitrate 
D) Spironolactone

Question 11

Which of the following is a b-adrenergic blocking drug that also has a-receptor blocking activity?

Accepted Answer

A) Atenolol 
B) Labetalol 
C) Doxazosin 
D) Minoxidil 
A) Atenolol 
B) Labetalol 
C) Doxazosin 
D) Minoxidil

Question 12

Which drug is a platelet aggregation inhibitor that has largely replaced ticlopidine?

Accepted Answer

A) Edoxaban (Savaysa) 
B) Dabigatran (Pradaxa) 
C) Clopidogrel (Plavix) 
D) Streptokinase (Streptase) 
E) Ticagrelor (Brilinta) 
A) Edoxaban (Savaysa) 
B) Dabigatran (Pradaxa) 
C) Clopidogrel (Plavix) 
D) Streptokinase (Streptase) 
E) Ticagrelor (Brilinta)

Question 13

Which diuretic acts at the ascending loop of Henle of the kidney nephron to cause rapid diuresis?

Accepted Answer

A) Hydrochlorothiazide 
B) Triamterine 
C) Furosemide 
D) Spironolactone 
A) Hydrochlorothiazide 
B) Triamterine 
C) Furosemide 
D) Spironolactone

Question 14

Which of the following statements is true of heart failure?

Accepted Answer

A) Usually the right side fails first. 
B) If the left side of the heart fails,the blood backs up into the pulmonary circulation. 
C) If the right side of the heart fails,then the left ventricle is unable to remove all the blood from the right side of the heart. 
D) Left-sided heart failure causes systemic congestion. 
A) Usually the right side fails first. 
B) If the left side of the heart fails,the blood backs up into the pulmonary circulation. 
C) If the right side of the heart fails,then the left ventricle is unable to remove all the blood from the right side of the heart. 
D) Left-sided heart failure causes systemic congestion.

Question 15

Nitroglycerine (NTG)is used for what cardiovascular disease?

Accepted Answer

A) Atherosclerosis 
B) Coronary artery disease 
C) Arrhythmias 
D) Angina pectoris 
A) Atherosclerosis 
B) Coronary artery disease 
C) Arrhythmias 
D) Angina pectoris

Question 16

What precautions should the dental professional exercise with a patient taking an á-adrenergic receptor blocker? (Select all that apply. )

Accepted Answer

A) Raise and lower the dental chair slowly. 
B) Use local anesthetic with no or low-dose epinephrine. 
C) Use caution and local measures for excessive bleeding tendency. 
D) Nonsteroidal antiinflammatory drugs (NSAIDs)will exacerbate the antihypertensive effect of the A₁-blockers to produce a hypertensive crisis. 
A) Raise and lower the dental chair slowly. 
B) Use local anesthetic with no or low-dose epinephrine. 
C) Use caution and local measures for excessive bleeding tendency. 
D) Nonsteroidal antiinflammatory drugs (NSAIDs)will exacerbate the antihypertensive effect of the A₁-blockers to produce a hypertensive crisis.

Question 17

PCSK9 inhibitors are

Accepted Answer

A) 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. 
B) antibodies. 
C) niacin. 
D) inhibitors of intestinal absorption of cholesterol. 
E) fibric acid derivatives. 
A) 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. 
B) antibodies. 
C) niacin. 
D) inhibitors of intestinal absorption of cholesterol. 
E) fibric acid derivatives.

Question 18

Which b-adrenergic blocking agent has partial agonist activity and causes some â-stimulation while blocking catecholamine action?

Accepted Answer

A) Atenolol 
B) Acebutolol 
C) Metoprolol 
D) Carvedilol 
A) Atenolol 
B) Acebutolol 
C) Metoprolol 
D) Carvedilol

Question 19

The cells of cardiac muscles have an intrinsic rhythm called

Accepted Answer

A) spontaneity. 
B) automaticity. 
C) anarchy. 
D) hierarchy. 
A) spontaneity. 
B) automaticity. 
C) anarchy. 
D) hierarchy.

Question 20

Which class of agents is of special benefit to a diabetic with nephropathy?

Accepted Answer

A) b-Adrenergic blockers 
B) Calcium channel blocker (CC
B)  
C) Angiotensin-converting enzyme inhibitors (ACEIs) 
D) Anticholinergics 
A) b-Adrenergic blockers 
B) Calcium channel blocker (CC
B)  
C) Angiotensin-converting enzyme inhibitors (ACEIs) 
D) Anticholinergics

Exam 12: Drugs for the Treatment of Cardiovascular Disease

Which of the following is the first choice of therapy for most patients with atherosclerotic heart disease and elevated cholesterol levels?

Statins are contraindicated as an antihyperlipidemic therapy in pregnant women.

Which of the following groups of diuretics are called the "puny" diuretics?

Which of the following statement is true concerning the use of b-adrenergic blocking agents for the treatment of angina pectoris?

Which of the following antibiotics can increase the toxicity of digoxin in some patients? (Select all that apply. )

Which antihypertensive agent is associated with a nonproductive cough?

The therapeutic target international normalized ratio (INR)for most indications,such as thrombophlebitis,is

Many _____ end in the suffix -pril.

Essential hypertension is

A serious lupus-like reaction is associated with which cardiovascular drug?

Which of the following is a b-adrenergic blocking drug that also has a-receptor blocking activity?

Which drug is a platelet aggregation inhibitor that has largely replaced ticlopidine?

Which diuretic acts at the ascending loop of Henle of the kidney nephron to cause rapid diuresis?

Which of the following statements is true of heart failure?

Nitroglycerine (NTG)is used for what cardiovascular disease?

What precautions should the dental professional exercise with a patient taking an á-adrenergic receptor blocker? (Select all that apply. )

PCSK9 inhibitors are

Which b-adrenergic blocking agent has partial agonist activity and causes some â-stimulation while blocking catecholamine action?

The cells of cardiac muscles have an intrinsic rhythm called

Which class of agents is of special benefit to a diabetic with nephropathy?

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