Question 1

Which of the following statements is true regarding the pharmacokinetics of acetaminophen?

Accepted Answer

A) Acetaminophen is slowly and incompletely absorbed from the gastrointestinal tract. 
B) Acetaminophen is excreted with a half-life of 8 to 12 hours. 
C) When large doses of acetaminophen are ingested,an intermediate metabolite is produced that is thought to be hepatotoxic. 
D) Acetaminophen is less potent and efficacious than aspirin. 
A) Acetaminophen is slowly and incompletely absorbed from the gastrointestinal tract. 
B) Acetaminophen is excreted with a half-life of 8 to 12 hours. 
C) When large doses of acetaminophen are ingested,an intermediate metabolite is produced that is thought to be hepatotoxic. 
D) Acetaminophen is less potent and efficacious than aspirin.

Question 2

A person should _____ aspirin if he or she suspects he or she may be having a heart attack provided there is not an aspirin allergy,hypersensitivity,or another contraindication.

Accepted Answer

A) completely avoid 
B) chew one low dose 
C) take the maximum daily recommended dose of 4,000 mg of 
D) take 325 to 650 mg every 4 hours of 
A) completely avoid 
B) chew one low dose 
C) take the maximum daily recommended dose of 4,000 mg of 
D) take 325 to 650 mg every 4 hours of

Question 3

Which of the following statements is true concerning adverse reactions of NSAIDs?

Accepted Answer

A) NSAIDs will decrease acid secretion in the stomach. 
B) Tolerance develops to the use of NSAIDs. 
C) NSAIDs irreversibly inhibit platelet aggregation because they inhibit thromboxane A₂ production. 
D) NSAIDs have precipitated renal insufficiency. 
A) NSAIDs will decrease acid secretion in the stomach. 
B) Tolerance develops to the use of NSAIDs. 
C) NSAIDs irreversibly inhibit platelet aggregation because they inhibit thromboxane A₂ production. 
D) NSAIDs have precipitated renal insufficiency.

Question 4

Which of the following drugs can be substituted for aspirin in patients displaying the aspirin hypersensitivity triad?

Accepted Answer

A) Ibuprofen 
B) Naproxen 
C) Codeine 
D) Piroxicam 
A) Ibuprofen 
B) Naproxen 
C) Codeine 
D) Piroxicam

Question 5

Two components of pain include perception and reaction.

Accepted Answer

A) True 
 B)False

Question 6

Which of the following agents is intended to treat an acute attack of gout?

Accepted Answer

A) Probenecid 
B) Codeine 
C) Colchicine 
D) Acetaminophen 
E) Both A and C 
A) Probenecid 
B) Codeine 
C) Colchicine 
D) Acetaminophen 
E) Both A and C

Question 7

Which of the following agents would be least useful in alleviating fever?

Accepted Answer

A) Piroxicam 
B) Acetaminophen 
C) Diflunisal 
D) Probenecid 
E) Aspirin 
A) Piroxicam 
B) Acetaminophen 
C) Diflunisal 
D) Probenecid 
E) Aspirin

Question 8

Caffeine is often combined with aspirin because caffeine potentiates the analgesic effect of aspirin and other analgesics.

Accepted Answer

A) Both parts of the statement are true. 
B) Both parts of the statement are false. 
C) The first part of the statement is true;the second part is false. 
D) The first part of the statement is false;the second part is true. 
A) Both parts of the statement are true. 
B) Both parts of the statement are false. 
C) The first part of the statement is true;the second part is false. 
D) The first part of the statement is false;the second part is true.

Question 9

All of the following are characteristics of aspirin toxicity (salicylism)except

Accepted Answer

A) dimness of vision. 
B) hyperthermia. 
C) electrolyte imbalance. 
D) hepatic necrosis. 
E) tinnitus. 
A) dimness of vision. 
B) hyperthermia. 
C) electrolyte imbalance. 
D) hepatic necrosis. 
E) tinnitus.

Question 10

The mechanism of action of nonopioid analgesics is due to

Accepted Answer

A) depression of the central nervous system (CNS). 
B) decrease in the pain threshold. 
C) inhibition of prostaglandin synthesis. 
D) stimulation of synthesis of prostaglandins. 
A) depression of the central nervous system (CNS). 
B) decrease in the pain threshold. 
C) inhibition of prostaglandin synthesis. 
D) stimulation of synthesis of prostaglandins.

Question 11

Salicylism is a toxic effect from

Accepted Answer

A) aspirin (AS
A) . 
B) acetaminophen (Tylenol). 
C) ibuprofen (Advil). 
D) azathioprine (Imuran). 
A) aspirin (AS
A) . 
B) acetaminophen (Tylenol). 
C) ibuprofen (Advil). 
D) azathioprine (Imuran).

Question 12

Acetaminophen does not possess any of these clinically significant _____ effects: (1)antipyretic, (2)antiinflammatory, (3)analgesic.

Accepted Answer

A) 1,2,3 
B) 1 and 2 
C) 1 and 3 
D) 1 
E) 2 
A) 1,2,3 
B) 1 and 2 
C) 1 and 3 
D) 1 
E) 2

Question 13

Aspirin can be used most safely in patients who

Accepted Answer

A) have arthritis. 
B) have gout. 
C) have ulcers. 
D) are pregnant. 
A) have arthritis. 
B) have gout. 
C) have ulcers. 
D) are pregnant.

Question 14

The ability of aspirin to reduce fever results from its inhibition of prostaglandin synthesis in the

Accepted Answer

A) medulla. 
B) hypothalamus. 
C) pons. 
D) cerebellum. 
A) medulla. 
B) hypothalamus. 
C) pons. 
D) cerebellum.

Question 15

The action of nonopioid analgesics is related to their ability to inhibit

Accepted Answer

A) the CNS. 
B) prostaglandin synthesis. 
C) release of epinephrine. 
D) release of acetylcholine. 
A) the CNS. 
B) prostaglandin synthesis. 
C) release of epinephrine. 
D) release of acetylcholine.

Question 16

Which of the following NSAIDs is the drug of choice for treating a nursing woman?

Accepted Answer

A) Naproxen 
B) Diflunisal 
C) Ibuprofen 
D) Fenoprofen 
A) Naproxen 
B) Diflunisal 
C) Ibuprofen 
D) Fenoprofen

Question 17

Pain

Accepted Answer

A) brings people to the dental office. 
B) keeps people from the dental office. 
C) can be effectively treated with inactive pills (placebos). 
D) does all of the above. 
A) brings people to the dental office. 
B) keeps people from the dental office. 
C) can be effectively treated with inactive pills (placebos). 
D) does all of the above.

Exam 5: Nonopioid Non-Narcoticanalgesics

Which of the following statements is true regarding the pharmacokinetics of acetaminophen?

A person should _____ aspirin if he or she suspects he or she may be having a heart attack provided there is not an aspirin allergy,hypersensitivity,or another contraindication.

Which of the following statements is true concerning adverse reactions of NSAIDs?

Which of the following drugs can be substituted for aspirin in patients displaying the aspirin hypersensitivity triad?

Two components of pain include perception and reaction.

Which of the following agents is intended to treat an acute attack of gout?

Which of the following agents would be least useful in alleviating fever?

Caffeine is often combined with aspirin because caffeine potentiates the analgesic effect of aspirin and other analgesics.

All of the following are characteristics of aspirin toxicity (salicylism)except

The mechanism of action of nonopioid analgesics is due to

Salicylism is a toxic effect from

Acetaminophen does not possess any of these clinically significant _____ effects: (1)antipyretic, (2)antiinflammatory, (3)analgesic.

Aspirin can be used most safely in patients who

The ability of aspirin to reduce fever results from its inhibition of prostaglandin synthesis in the

The action of nonopioid analgesics is related to their ability to inhibit

Which of the following NSAIDs is the drug of choice for treating a nursing woman?

Pain

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