Question 1

Drugs that are weak electrolytes will cross body membranes best when they are (1)nonionized, (2)ionized, (3)polar, (4)nonpolar, (5)lipid soluble, (6)water soluble.

Accepted Answer

A) 1,3,5 
B) 1,3,6 
C) 1,4,5 
D) 1,4,6 
E) 2,4,5 
A) 1,3,5 
B) 1,3,6 
C) 1,4,5 
D) 1,4,6 
E) 2,4,5

Question 2

Which of the following reactions is considered to be in the category of phase II drug metabolism?

Accepted Answer

A) Conjugation 
B) Reduction 
C) Hydrolysis 
D) Oxidation 
A) Conjugation 
B) Reduction 
C) Hydrolysis 
D) Oxidation

Question 3

A prodrug is an example of which type mechanism of metabolism?

Accepted Answer

A) Active to active 
B) Active to inactive 
C) Inactive to active 
D) Inactive to inactive 
A) Active to active 
B) Active to inactive 
C) Inactive to active 
D) Inactive to inactive

Question 4

Which of the following statements is true concerning the mechanism of action of drugs?

Accepted Answer

A) Drugs are capable of imparting a new function to the organism. 
B) Drugs either produce the same action as an exogenous agent or block the action of an exogenous agent. 
C) Drugs either produce the same action as an exogenous agent or block the action of an endogenous agent. 
D) Drugs either produce the same action as an endogenous agent or block the action of an endogenous agent. 
A) Drugs are capable of imparting a new function to the organism. 
B) Drugs either produce the same action as an exogenous agent or block the action of an exogenous agent. 
C) Drugs either produce the same action as an exogenous agent or block the action of an endogenous agent. 
D) Drugs either produce the same action as an endogenous agent or block the action of an endogenous agent.

Question 5

Which of the following statements is true regarding the therapeutic index (TI)of a drug?

Accepted Answer

A) A drug with a large TI is more dangerous than a drug with a small TI. 
B) The formula for TI is ED50/LD50. 
C) ED50 is 50% of the effective clinical dose. 
D) TI is the ratio of the median lethal dose to the median effective dose. 
A) A drug with a large TI is more dangerous than a drug with a small TI. 
B) The formula for TI is ED50/LD50. 
C) ED50 is 50% of the effective clinical dose. 
D) TI is the ratio of the median lethal dose to the median effective dose.

Question 6

When different drugs compete for the same receptor sites,the drug with the stronger affinity for the receptor will bind to

Accepted Answer

A) more receptors than the drug with the weaker affinity. 
B) fewer receptors than the drug with the weaker affinity. 
C) all of the available receptors. 
D) none of the available receptors. 
A) more receptors than the drug with the weaker affinity. 
B) fewer receptors than the drug with the weaker affinity. 
C) all of the available receptors. 
D) none of the available receptors.

Question 7

Which drug is eliminated with zero-order kinetics?

Accepted Answer

A) Probenecid 
B) Aspirin 
C) Allopurinol 
D) Penicillin 
E) Naproxyn sodium 
A) Probenecid 
B) Aspirin 
C) Allopurinol 
D) Penicillin 
E) Naproxyn sodium

Question 8

If redistribution occurs between specific sites and nonspecific sites,a drug's action will be

Accepted Answer

A) prolonged. 
B) extended. 
C) decreased. 
D) terminated. 
A) prolonged. 
B) extended. 
C) decreased. 
D) terminated.

Question 9

When a drug has affinity for a receptor and produces no effect,it is called a(n)

Accepted Answer

A) agonist. 
B) competitive antagonist. 
C) competitive agonist. 
D) physiologic agonist. 
A) agonist. 
B) competitive antagonist. 
C) competitive agonist. 
D) physiologic agonist.

Question 10

Drugs,after undergoing phase I drug metabolism,are more likely to be distributed to fat tissue.

Accepted Answer

A) True 
 B)False

Question 11

What of the following choices is considered the safest,least expensive,and most convenient route for administering drugs?

Accepted Answer

A) Inhalation 
B) Rectal 
C) Oral 
D) Subcutaneous 
A) Inhalation 
B) Rectal 
C) Oral 
D) Subcutaneous

Question 12

One dose of a drug is administered that has a half-life of 8 hours.Assuming first-order kinetics,how much time is needed for this drug to be over 96% eliminated from the body?

Accepted Answer

A) 8 hours 
B) 40 hours 
C) 60 hours 
D) 120 hours 
A) 8 hours 
B) 40 hours 
C) 60 hours 
D) 120 hours

Question 13

The route of administration of a drug affects

Accepted Answer

A) both the onset and duration of response. 
B) the onset,but not the duration of response. 
C) the duration,but not the onset of response. 
D) neither the onset nor the duration of response. 
A) both the onset and duration of response. 
B) the onset,but not the duration of response. 
C) the duration,but not the onset of response. 
D) neither the onset nor the duration of response.

Question 14

If a drug is a weak base that is excreted via the kidneys,then acidifying the urine will enhance its excretion.

Accepted Answer

A) True 
 B)False

Drugs that are weak electrolytes will cross body membranes best when they are (1)nonionized, (2)ionized, (3)polar, (4)nonpolar, (5)lipid soluble, (6)water soluble.

Which of the following reactions is considered to be in the category of phase II drug metabolism?

A prodrug is an example of which type mechanism of metabolism?

Which of the following statements is true concerning the mechanism of action of drugs?

Which of the following statements is true regarding the therapeutic index (TI)of a drug?

When different drugs compete for the same receptor sites,the drug with the stronger affinity for the receptor will bind to

Which drug is eliminated with zero-order kinetics?

If redistribution occurs between specific sites and nonspecific sites,a drug's action will be

When a drug has affinity for a receptor and produces no effect,it is called a(n)

Drugs,after undergoing phase I drug metabolism,are more likely to be distributed to fat tissue.

What of the following choices is considered the safest,least expensive,and most convenient route for administering drugs?

One dose of a drug is administered that has a half-life of 8 hours.Assuming first-order kinetics,how much time is needed for this drug to be over 96% eliminated from the body?

The route of administration of a drug affects

If a drug is a weak base that is excreted via the kidneys,then acidifying the urine will enhance its excretion.

Information Sources, Regulatory Agencies, Drug Legislation, and Prescription Writing

Adverse Reactions

Autonomic Drugs

Nonopioid Non-Narcoticanalgesics

Opioid Narcoticanalgesics and Antagonists

Antiinfective Agents

Antifungal and Antiviral Agents

Local Anesthetics

General Anesthetics

Antianxiety Agents

Drugs for the Treatment of Cardiovascular Disease

Drugs for the Treatment of Gastrointestinal Diseases

Drugs for the Treatment of Seizure Disorders

Drugs for the Treatment of Central Nervous System Disorders

Adrenocorticosteroids

Drugs for the Treatment of Respiratory Disorders and Allergic Rhinitis

Drugs for the Treatment of Diabetes Mellitus

Drugs for the Treatment of Other Endocrine Disorders

Antineoplastic Drugs

Emergency Drugs

Pregnancy and Breast Feeding

Substance Use Disorders

Naturalherbal Products and Dietary Supplements

Oral Conditions and Their Treatment

Hygiene-Related Oral Disorders

Filters

Exam 2: Drug Action and Handling

Drugs that are weak electrolytes will cross body membranes best when they are (1)nonionized, (2)ionized, (3)polar, (4)nonpolar, (5)lipid soluble, (6)water soluble.

Which of the following reactions is considered to be in the category of phase II drug metabolism?

A prodrug is an example of which type mechanism of metabolism?

Which of the following statements is true concerning the mechanism of action of drugs?

Which of the following statements is true regarding the therapeutic index (TI)of a drug?

When different drugs compete for the same receptor sites,the drug with the stronger affinity for the receptor will bind to

Which drug is eliminated with zero-order kinetics?

If redistribution occurs between specific sites and nonspecific sites,a drug's action will be

When a drug has affinity for a receptor and produces no effect,it is called a(n)

Drugs,after undergoing phase I drug metabolism,are more likely to be distributed to fat tissue.

What of the following choices is considered the safest,least expensive,and most convenient route for administering drugs?

One dose of a drug is administered that has a half-life of 8 hours.Assuming first-order kinetics,how much time is needed for this drug to be over 96% eliminated from the body?

The route of administration of a drug affects

If a drug is a weak base that is excreted via the kidneys,then acidifying the urine will enhance its excretion.

Information Sources, Regulatory Agencies, Drug Legislation, and Prescription Writing

Adverse Reactions

Autonomic Drugs

Nonopioid Non-Narcoticanalgesics

Opioid Narcoticanalgesics and Antagonists

Antiinfective Agents

Antifungal and Antiviral Agents

Local Anesthetics

General Anesthetics

Antianxiety Agents

Drugs for the Treatment of Cardiovascular Disease

Drugs for the Treatment of Gastrointestinal Diseases

Drugs for the Treatment of Seizure Disorders

Drugs for the Treatment of Central Nervous System Disorders

Adrenocorticosteroids

Drugs for the Treatment of Respiratory Disorders and Allergic Rhinitis

Drugs for the Treatment of Diabetes Mellitus

Drugs for the Treatment of Other Endocrine Disorders

Antineoplastic Drugs

Emergency Drugs

Pregnancy and Breast Feeding

Substance Use Disorders

Naturalherbal Products and Dietary Supplements

Oral Conditions and Their Treatment

Hygiene-Related Oral Disorders

Filters