Exam 14: Surfactant Replacement

What is the role of SP-D in human pulmonary surfactant? I.Suppresses proinflammatory responses II.Enhances phagocytosis III.Enhances killing of microbes IV.Functions as an opsonin for bacteria

A pregnant woman believed to be at 26 weeks gestation has been admitted for premature labor.What should be administered to this woman to decrease the risk of RDS if the infant is delivered prematurely?

According to Laplace's law the pressure required to open an alveoli in the lung is:

Which of the following physiologic consequences would develop if the liquid-gas interface were without surfactant?

Which of the following is the most common form of surfactant abnormality associated with acute lung injury?

How do synthetic surfactants compare with bovine surfactants?

A term baby with meconium aspiration syndrome is receiving mechanical ventilation per protocol.On the third day,the therapist observes that the FiO₂ requirement is increasing and both lung compliance and oxygenation index are worsening.What should be suggested at this time?

The respiratory therapist administering surfactant to a premature newborn notices a significant deterioration in vital signs.What should be done at this time?

Which of the following is the most important component of pulmonary surfactant? I.Dipalmitoyl phosphatidylcholine II.Phosphatidylglycerine III.Phosphatidylinositol IV.Sphingomyelin

A full-term infant received surfactant as rescue therapy for RDS.Despite redosing,the infant has not been able to be extubated during the first 2 weeks of life.What should this neonate be evaluated for?

Which of the following clinical conditions should be suspected in a neonate unresponsive to surfactant due to its inactivation?

Which of the following physiologic conditions result from the presence of normal amounts of pulmonary surfactant in the lung?

What appears to be the benefit of administering prophylactic surfactant replacement therapy to preterm infants? I.Decreased risk of mortality II.Reduced threat of pneumothorax III.Decreased incidence of diaphragmatic hernia IV.Reduced risk of developing pulmonary interstitial emphysema

Which of the following relationships is correct regarding the analysis of amniotic fluid to determine fetal lung maturity?