Question 1

A symptomatic congenital infection with cytomegalovirus (CMV)includes all the following symptoms EXCEPT:

Accepted Answer

A)  Hepatosplenomegaly 
B)  Microcephaly 
C)  Chorioretinitis 
D)  Meningitis 
A)  Hepatosplenomegaly 
B)  Microcephaly 
C)  Chorioretinitis 
D)  Meningitis

Question 2

What virus causes genital herpes?

Accepted Answer

A)  Human herpesvirus 6 (HHV-6) 
B)  Cytomegalovirus (CMV) 
C)  Herpes simplex virus type 2 (HSV-2) 
D)  Human herpesvirus (HHV-5) 
A)  Human herpesvirus 6 (HHV-6) 
B)  Cytomegalovirus (CMV) 
C)  Herpes simplex virus type 2 (HSV-2) 
D)  Human herpesvirus (HHV-5)

Question 3

When is the best time to collect a specimen from a patient suspected of having a viral disease?

Accepted Answer

A)  1 week after onset of symptoms 
B)  5 days after onset of symptoms 
C)  Less than 3 days after onset of symptoms 
D)  2 weeks after onset of symptoms 
A)  1 week after onset of symptoms 
B)  5 days after onset of symptoms 
C)  Less than 3 days after onset of symptoms 
D)  2 weeks after onset of symptoms

Question 4

All the following methods are used by the laboratory to diagnose viral infections EXCEPT:

Accepted Answer

A)  Chemiluminescence 
B)  Direct detection 
C)  Culture 
D)  Serologic assays 
A)  Chemiluminescence 
B)  Direct detection 
C)  Culture 
D)  Serologic assays

Question 5

Complications of Epstein-Barr virus (EBV)infection include all the following EXCEPT:

Accepted Answer

A)  Acute glomerulonephritis 
B)  Reye's syndrome 
C)  Thrombocytopenia purpura with hemolytic anemia 
D)  Splenic hemorrhage and rupture 
A)  Acute glomerulonephritis 
B)  Reye's syndrome 
C)  Thrombocytopenia purpura with hemolytic anemia 
D)  Splenic hemorrhage and rupture

Question 6

All of the following are problems that are inherent with using serologic methods to diagnose viral infections,EXCEPT:

Accepted Answer

A)  The host does not produce specific antibodies to viruses. 
B)  Serologic assays measure host response rather than directly detecting the virus. 
C)  The antibody-producing capabilities of human hosts vary widely. 
D)  The antibody level does not correlate with the activity level of the infection. 
A)  The host does not produce specific antibodies to viruses. 
B)  Serologic assays measure host response rather than directly detecting the virus. 
C)  The antibody-producing capabilities of human hosts vary widely. 
D)  The antibody level does not correlate with the activity level of the infection.

Question 7

What is a diploid cell culture?

Accepted Answer

A)  This is where tissue is removed from an animal, arranged in a monolayer, and very little cell division occurs. 
B)  It is a culture that can divide, but passage is limited to 50 generations. 
C)  It has variable numbers of chromosomes and indefinite passage. 
D)  This describes the only cells the specimen will be plated on. 
A)  This is where tissue is removed from an animal, arranged in a monolayer, and very little cell division occurs. 
B)  It is a culture that can divide, but passage is limited to 50 generations. 
C)  It has variable numbers of chromosomes and indefinite passage. 
D)  This describes the only cells the specimen will be plated on.

Question 8

What is the most common flavivirus infection in the United States?

Accepted Answer

A)  West Nile virus 
B)  Eastern equine encephalitis virus 
C)  St. Louis encephalitis 
D)  Rocky Mountain spotted fever 
A)  West Nile virus 
B)  Eastern equine encephalitis virus 
C)  St. Louis encephalitis 
D)  Rocky Mountain spotted fever

Question 9

What is another name for HHV-5?

Accepted Answer

A)  Varicella-zoster 
B)  Cytomegalovirus 
C)  Herpes simplex 
D)  Epstein-Barr 
A)  Varicella-zoster 
B)  Cytomegalovirus 
C)  Herpes simplex 
D)  Epstein-Barr

Question 10

What type of genome do herpesviruses have?

Accepted Answer

A)  SsDNA 
B)  RNA 
C)  DsDNA 
D)  Both dsDNA and RNA 
A)  SsDNA 
B)  RNA 
C)  DsDNA 
D)  Both dsDNA and RNA

Question 11

All the following viruses cause hemorrhagic fever with renal syndrome (HFRS)EXCEPT:

Accepted Answer

A)  Hantaan virus 
B)  Seoul virus 
C)  Dobrava virus 
D)  Calicivirus 
A)  Hantaan virus 
B)  Seoul virus 
C)  Dobrava virus 
D)  Calicivirus

Question 12

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

Accepted Answer

A)  Giant cells 
B)  Macrophages 
C)  Glial cells 
D)  Syncytia 
A)  Giant cells 
B)  Macrophages 
C)  Glial cells 
D)  Syncytia

Question 13

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

Accepted Answer

A)  4° C 
B)  -10° C 
C)  -20° C 
D)  -70° C 
A)  4° C 
B)  -10° C 
C)  -20° C 
D)  -70° C

Question 14

What is the cytopathic effect?

Accepted Answer

A)  The way viruses kill the host cell 
B)  The visual changes produced in a cell by a virus 
C)  The tears that the virus puts in a host cell's membrane 
D)  The way the virus lyses the cell after all the new virus particles are formed and ready to be released. 
A)  The way viruses kill the host cell 
B)  The visual changes produced in a cell by a virus 
C)  The tears that the virus puts in a host cell's membrane 
D)  The way the virus lyses the cell after all the new virus particles are formed and ready to be released.

Question 15

What disease does the varicella zoster virus (VZV)cause?

Accepted Answer

A)  Mumps 
B)  Genital warts 
C)  Chickenpox 
D)  Rubella 
A)  Mumps 
B)  Genital warts 
C)  Chickenpox 
D)  Rubella

Question 16

Which virus is a blood-borne pathogen?

Accepted Answer

A)  Hepatitis A virus (HAV) 
B)  Rabies 
C)  Hepatitis C virus (HCV) 
D)  Norovirus 
A)  Hepatitis A virus (HAV) 
B)  Rabies 
C)  Hepatitis C virus (HCV) 
D)  Norovirus

Question 17

All the following are direct methods for diagnosing viral infections EXCEPT:

Accepted Answer

A)  Indirect fluorescent antibody (IF
A)  
B)  Direct fluorescent antibody (DF
A)  
C)  Radioimmunoassay (RI
A)  
D)  Enzyme immunoassay (EI
A)  
A)  Indirect fluorescent antibody (IF
A)  
B)  Direct fluorescent antibody (DF
A)  
C)  Radioimmunoassay (RI
A)  
D)  Enzyme immunoassay (EI
A)

Question 18

What was the first arenavirus found to cause hemorrhagic fever?

Accepted Answer

A)  Ebola 
B)  Malta 
C)  Junin 
D)  Marburg 
A)  Ebola 
B)  Malta 
C)  Junin 
D)  Marburg

Question 19

What is the genome of a virus composed of?

Accepted Answer

A)  Single-stranded DNA 
B)  RNA 
C)  Double-stranded DNA 
D)  Any of the above 
A)  Single-stranded DNA 
B)  RNA 
C)  Double-stranded DNA 
D)  Any of the above

Question 20

Adenoviruses produce all the following types of infections EXCEPT:

Accepted Answer

A)  Acute hemorrhagic cystitis 
B)  Meningitis 
C)  Acute respiratory distress 
D)  Epidemic keratoconjunctivitis 
A)  Acute hemorrhagic cystitis 
B)  Meningitis 
C)  Acute respiratory distress 
D)  Epidemic keratoconjunctivitis

Exam 29: Clinical Virology

A symptomatic congenital infection with cytomegalovirus (CMV)includes all the following symptoms EXCEPT:

What virus causes genital herpes?

When is the best time to collect a specimen from a patient suspected of having a viral disease?

All the following methods are used by the laboratory to diagnose viral infections EXCEPT:

Complications of Epstein-Barr virus (EBV)infection include all the following EXCEPT:

All of the following are problems that are inherent with using serologic methods to diagnose viral infections,EXCEPT:

What is a diploid cell culture?

What is the most common flavivirus infection in the United States?

What is another name for HHV-5?

What type of genome do herpesviruses have?

All the following viruses cause hemorrhagic fever with renal syndrome (HFRS)EXCEPT:

What are giant multinucleated cells formed from cell fusion as a result of viral infection?

What is an unsuitable storage temperature for viruses because it allows the development of ice crystals?

What is the cytopathic effect?

What disease does the varicella zoster virus (VZV)cause?

Which virus is a blood-borne pathogen?

All the following are direct methods for diagnosing viral infections EXCEPT:

What was the first arenavirus found to cause hemorrhagic fever?

What is the genome of a virus composed of?

Adenoviruses produce all the following types of infections EXCEPT:

Bacterial Cell Structure, physiology, Metabolism, and Genetics

Host-Parasite Interaction

Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Infected Materials

Use of Colonial Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antibiotic Mechanisms of Action and Resistance

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, enterococcus, and Other Catalase-Negative Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio,aeromonas,plesiomonas and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

Spirochetes

Chlamydia and Rickettsia

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Other Nontuberculosis Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Agents of Bioterror

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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