Exam 45: Antineoplastic and Immunomodulating Drugs

Which drug reduces the supply of 5,10-methylene-tetrahydrofolate and thereby prevents formation of deoxythymidine monophosphate?

A woman is placed on a drug that colors the urine red. Which agent has been used to protect against the cardiac toxicity caused by this drug?

A man receives a monoclonal antibody for colorectal cancer. This agent binds to which target protein?

Increased expression of the P-glycoprotein is most likely to cause cancer cell resistance to which drug?

A woman with ovarian cancer receives a drug that inhibits cancer cell mitosis. What is the dose-limiting adverse effect of this drug?

Which drug increases expression of pro-apoptosis factors and reduces expression of cyclins in chronic myeloid leukemia cells?