Question 1

Memantine is believed to benefit persons with Alzheimer's disease because of its ability to exert which action?

Accepted Answer

A)  inhibit neurotransmitter degradation 
B)  increase neurotransmitter degradation 
C)  block neurotransmitter receptors 
D)  activate neurotransmitter receptors 
E)  block neurotransmitter reuptake 
A)  inhibit neurotransmitter degradation 
B)  increase neurotransmitter degradation 
C)  block neurotransmitter receptors 
D)  activate neurotransmitter receptors 
E)  block neurotransmitter reuptake C

Question 2

Which agent is useful in persons with multiple sclerosis because it serves as a decoy for myelin-damaging T cells?

Accepted Answer

A)  mitoxantrone 
B)  natalizumab 
C)  interferon beta-1b 
D)  glatiramer 
E)  prednisone 
A)  mitoxantrone 
B)  natalizumab 
C)  interferon beta-1b 
D)  glatiramer 
E)  prednisone D

Question 3

Severe hypomobility ("freezing") reactions in advanced Parkinson's disease may respond rapidly after injection of which drug?

Accepted Answer

A)  apomorphine 
B)  dopamine 
C)  ropinirole 
D)  benztropine 
E)  tizanidine 
A)  apomorphine 
B)  dopamine 
C)  ropinirole 
D)  benztropine 
E)  tizanidine A

Question 4

Which action is responsible for the therapeutic effects of entacapone?

Accepted Answer

A)  inhibition of monoamine oxidase-type B 
B)  stimulation of levodopa decarboxylation 
C)  decreased formation of 3-O-methyldopa 
D)  increased uptake of dopamine into the brain 
E)  increased release of dopamine from neurons 
A)  inhibition of monoamine oxidase-type B 
B)  stimulation of levodopa decarboxylation 
C)  decreased formation of 3-O-methyldopa 
D)  increased uptake of dopamine into the brain 
E)  increased release of dopamine from neurons

Exam 24: Drugs for Neurodegenerative Diseases

Memantine is believed to benefit persons with Alzheimer's disease because of its ability to exert which action?

Which agent is useful in persons with multiple sclerosis because it serves as a decoy for myelin-damaging T cells?

Severe hypomobility ("freezing") reactions in advanced Parkinson's disease may respond rapidly after injection of which drug?

Which action is responsible for the therapeutic effects of entacapone?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiviral Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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