Question 1

For which reason is lorazepam is one of the safer benzodiazepines for elderly patients?

Accepted Answer

A)  It is excreted unchanged in the urine. 
B)  It does not cause anterograde amnesia. 
C)  It is not associated with drug dependence. 
D)  It is metabolized by glucuronide formation. 
E)  It has special utility in treating panic disorder. 
A)  It is excreted unchanged in the urine. 
B)  It does not cause anterograde amnesia. 
C)  It is not associated with drug dependence. 
D)  It is metabolized by glucuronide formation. 
E)  It has special utility in treating panic disorder. D

Question 2

Which attribute is correctly associated with ramelteon?

Accepted Answer

A)  produces considerable daytime sedation 
B)  may cause rebound insomnia when discontinued 
C)  has a high abuse potential 
D)  binds melatonin receptors 
E)  is a Schedule IV controlled substance 
A)  produces considerable daytime sedation 
B)  may cause rebound insomnia when discontinued 
C)  has a high abuse potential 
D)  binds melatonin receptors 
E)  is a Schedule IV controlled substance D

Question 3

Which property is related to the ability of zolpidem to selectively bind GABAA receptors that are composed of α ₁-subunits?

Accepted Answer

A)  lack of active metabolites 
B)  low degree of daytime sedation 
C)  low potential for drug dependence 
D)  greater effect on REM sleep 
E)  greater effect on slow wave sleep 
A)  lack of active metabolites 
B)  low degree of daytime sedation 
C)  low potential for drug dependence 
D)  greater effect on REM sleep 
E)  greater effect on slow wave sleep C

Question 4

Because of its ability to induce α-aminolevulinate synthase, phenobarbital should not be taken in persons with which disorder?

Accepted Answer

A)  porphyria 
B)  homocystinuria 
C)  pernicious anemia 
D)  hemophilia 
E)  hepatitis 
A)  porphyria 
B)  homocystinuria 
C)  pernicious anemia 
D)  hemophilia 
E)  hepatitis

Exam 19: Sedative-Hypnotic and Anxiolytic Drugs

For which reason is lorazepam is one of the safer benzodiazepines for elderly patients?

Which attribute is correctly associated with ramelteon?

Which property is related to the ability of zolpidem to selectively bind GABAA receptors that are composed of α ₁-subunits?

Because of its ability to induce α-aminolevulinate synthase, phenobarbital should not be taken in persons with which disorder?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

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Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

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Antifungal Drugs

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