Question 1

A man receives a drug that binds to chemokine co-receptor 5. Which step in viral replication is prevented by this drug?

Accepted Answer

A)  binding of viral glycoprotein120 to host CD4 cells 
B)  transfer of viral nucleic acid into host cells 
C)  formation of a DNA copy of viral RNA 
D)  integration of viral DNA into host cell genome 
E)  expression of viral proteins 
A)  binding of viral glycoprotein120 to host CD4 cells 
B)  transfer of viral nucleic acid into host cells 
C)  formation of a DNA copy of viral RNA 
D)  integration of viral DNA into host cell genome 
E)  expression of viral proteins B

Question 2

Which antiviral agent is active against viruses that cause several hemorrhagic fevers, such as Rift Valley fever virus?

Accepted Answer

A)  ganciclovir 
B)  lamivudine 
C)  interferon alfa 
D)  foscarnet 
E)  ribavirin 
A)  ganciclovir 
B)  lamivudine 
C)  interferon alfa 
D)  foscarnet 
E)  ribavirin E

Question 3

A woman is placed on a drug that binds HIV reverse transcriptase and is being monitored for drug-induced neuropsychiatric reactions. This drug should not be taken by persons with which condition?

Accepted Answer

A)  cardiac arrhythmia 
B)  hypercholesterolemia 
C)  pancreatitis 
D)  pregnancy 
E)  diabetic neuropathy 
A)  cardiac arrhythmia 
B)  hypercholesterolemia 
C)  pancreatitis 
D)  pregnancy 
E)  diabetic neuropathy D

Question 4

A man receives a drug that binds cations essential for the catalytic activity of an enzyme required for HIV replication. Which step is blocked by this drug?

Accepted Answer

A)  viral maturation and release 
B)  interaction of the viral enzyme and host cell DNA 
C)  insertion of glycoprotein 41 into host cell membranes 
D)  formation of a DNA copy of viral RNA 
E)  binding of glycoprotein 120 to CD4 antigen 
A)  viral maturation and release 
B)  interaction of the viral enzyme and host cell DNA 
C)  insertion of glycoprotein 41 into host cell membranes 
D)  formation of a DNA copy of viral RNA 
E)  binding of glycoprotein 120 to CD4 antigen

Exam 43: Antiviral Drugs

A man receives a drug that binds to chemokine co-receptor 5. Which step in viral replication is prevented by this drug?

Which antiviral agent is active against viruses that cause several hemorrhagic fevers, such as Rift Valley fever virus?

A woman is placed on a drug that binds HIV reverse transcriptase and is being monitored for drug-induced neuropsychiatric reactions. This drug should not be taken by persons with which condition?

A man receives a drug that binds cations essential for the catalytic activity of an enzyme required for HIV replication. Which step is blocked by this drug?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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