Question 1

Which drug action prevents precocious sexual development in boys being treated for congenital adrenal hyperplasia?

Accepted Answer

A)  suppression of corticotropin secretion 
B)  activation of adrenal steroid receptors 
C)  stimulation of adrenal 11-β -hydroxylase 
D)  stimulation of adrenal 21-hydroxylase 
E)  inhibition androgen pathway enzymes 
A)  suppression of corticotropin secretion 
B)  activation of adrenal steroid receptors 
C)  stimulation of adrenal 11-β -hydroxylase 
D)  stimulation of adrenal 21-hydroxylase 
E)  inhibition androgen pathway enzymes A

Question 2

After receiving prednisone for several months, a woman develops fat deposits in the upper back.
Which drug action contributes to this adverse effect?

Accepted Answer

A)  increased gluconeogenesis 
B)  increased protein catabolism 
C)  increased glucose uptake by adipose tissue 
D)  increased glycogenolysis 
E)  increased lipolysis 
A)  increased gluconeogenesis 
B)  increased protein catabolism 
C)  increased glucose uptake by adipose tissue 
D)  increased glycogenolysis 
E)  increased lipolysis E

Question 3

A patient is treated with a drug that increases expression of genes encoding sodium channels and the sodium-potassium ATPase. Which effect will result from this action?

Accepted Answer

A)  increased free water clearance 
B)  increased sodium excretion 
C)  increased potassium excretion 
D)  increased calcium excretion 
E)  increased aldosterone secretion 
A)  increased free water clearance 
B)  increased sodium excretion 
C)  increased potassium excretion 
D)  increased calcium excretion 
E)  increased aldosterone secretion C

Exam 33: Adrenal Steroids and Related Drugs

Which drug action prevents precocious sexual development in boys being treated for congenital adrenal hyperplasia?

After receiving prednisone for several months, a woman develops fat deposits in the upper back. Which drug action contributes to this adverse effect?

A patient is treated with a drug that increases expression of genes encoding sodium channels and the sodium-potassium ATPase. Which effect will result from this action?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Psychotherapeutic Drugs

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiviral Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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