Question 1

Which adverse effect is most often associated with lithium carbonate therapy?

Accepted Answer

A)  tachycardia 
B)  hyperventilation 
C)  sexual dysfunction 
D)  increased urinary output 
E)  hypervolemic hyponatremia 
A)  tachycardia 
B)  hyperventilation 
C)  sexual dysfunction 
D)  increased urinary output 
E)  hypervolemic hyponatremia D

Question 2

A man with schizophrenia experiences fewer extrapyramidal symptoms after his drug therapy was switched to aripiprazole. Which attribute of aripiprazole most likely contributes to this improvement?

Accepted Answer

A)  partial agonist at dopamine receptors 
B)  partial agonist at serotonin receptors 
C)  full agonist at dopamine receptors 
D)  full agonist at serotonin receptors 
E)  antagonist at both serotonin and dopamine receptors 
A)  partial agonist at dopamine receptors 
B)  partial agonist at serotonin receptors 
C)  full agonist at dopamine receptors 
D)  full agonist at serotonin receptors 
E)  antagonist at both serotonin and dopamine receptors A

Question 3

A woman is evaluated to determine the cause of infertility and is found to have elevated serum prolactin levels. Which drug is most likely responsible for this adverse effect?

Accepted Answer

A)  fluoxetine 
B)  lithium 
C)  haloperidol 
D)  aripiprazole 
E)  bupropion 
A)  fluoxetine 
B)  lithium 
C)  haloperidol 
D)  aripiprazole 
E)  bupropion C

Question 4

A woman is placed on an antidepressant that increases neuronal release of norepinephrine. Which mechanism is responsible for this effect?

Accepted Answer

A)  activation of α 2-adrenoceptors 
B)  blockade of α 2-adrenoceptors 
C)  activation of serotonin 5-HT2 receptors 
D)  blockade of serotonin 5-HT2 receptors 
E)  blockade of muscarinic acetylcholine receptors 
A)  activation of α 2-adrenoceptors 
B)  blockade of α 2-adrenoceptors 
C)  activation of serotonin 5-HT2 receptors 
D)  blockade of serotonin 5-HT2 receptors 
E)  blockade of muscarinic acetylcholine receptors

Question 5

The efficacy of atomoxetine in persons with attention-deficit/hyperactivity disorder is due to which mechanism?

Accepted Answer

A)  inhibition of norepinephrine reuptake 
B)  stimulation of norepinephrine synthesis 
C)  blockade of adrenoceptors 
D)  activation of adrenoceptors 
E)  increased release of norepinephrine 
A)  inhibition of norepinephrine reuptake 
B)  stimulation of norepinephrine synthesis 
C)  blockade of adrenoceptors 
D)  activation of adrenoceptors 
E)  increased release of norepinephrine

Question 6

Several weeks after beginning drug therapy, a man experiences impotence,
Erectile dysfunction,
And impaired ejaculation.
Which agent is most likely responsible for these adverse effects?

Accepted Answer

A)  lithium 
B)  bupropion 
C)  sertraline 
D)  risperidone 
E)  desipramine 
A)  lithium 
B)  bupropion 
C)  sertraline 
D)  risperidone 
E)  desipramine

Exam 22: Psychotherapeutic Drugs

Which adverse effect is most often associated with lithium carbonate therapy?

A man with schizophrenia experiences fewer extrapyramidal symptoms after his drug therapy was switched to aripiprazole. Which attribute of aripiprazole most likely contributes to this improvement?

A woman is evaluated to determine the cause of infertility and is found to have elevated serum prolactin levels. Which drug is most likely responsible for this adverse effect?

A woman is placed on an antidepressant that increases neuronal release of norepinephrine. Which mechanism is responsible for this effect?

The efficacy of atomoxetine in persons with attention-deficit/hyperactivity disorder is due to which mechanism?

Several weeks after beginning drug therapy, a man experiences impotence, Erectile dysfunction, And impaired ejaculation. Which agent is most likely responsible for these adverse effects?

Introduction to Pharmacology

Pharmacokinetics

Pharmacodynamics

Drug Development and Safety

Introduction to Autonomic and Neuromuscular Pharmacology

Acetylcholine Receptor Agonists

Acetylcholine Receptor Antagonists

Adrenoceptor Agonists

Adrenoceptor Antagonists

Antihypertensive Drugs

Antianginal Drugs

Drugs for Heart Failure

Diuretics

Antiarrhythmic Drugs

Drugs for Hyperlipidemia

Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Hematopoietic Drugs

Introduction to Central Nervous System Pharmacology

Sedative-Hypnotic and Anxiolytic Drugs

Antiepileptic Drugs

Local and General Anesthetics

Opioid Analgesics and Antagonists

Drugs for Neurodegenerative Diseases

Drugs of Abuse

Autacoid Drugs

Drugs for Respiratory Tract Disorders

Drugs for Gastrointestinal Tract Disorders

Drugs for Headache Disorders

Drugs for Pain, Inflammation, and Arthritic Disorders

Hypothalamic and Pituitary Drugs

Thyroid Drugs

Adrenal Steroids and Related Drugs

Drugs Affecting Fertility and Reproduction

Drugs for Diabetes Mellitus

Drugs Affecting Calcium and Bone

Principles of Antimicrobial Chemotherapy

Inhibitors of Bacterial Cell Wall Synthesis

Inhibitors of Bacterial Protein Synthesis

Quinolones, Antifolate Drugs, and Other Antimicrobial Agents

Antimycobacterial Drugs

Antifungal Drugs

Antiviral Drugs

Antiparasitic Drugs

Antineoplastic and Immunomodulating Drugs

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