Question 1

Almost a century after Edward Jenner introduced successful vaccination,Louis Pasteur developed vaccine(s)against

Accepted Answer

A)  anthrax. 
B)  human cholera. 
C)  rabies. 
D)  influenza. 
E)  both anthrax and rabies. 
A)  anthrax. 
B)  human cholera. 
C)  rabies. 
D)  influenza. 
E)  both anthrax and rabies.

Question 2

An advantage of (attenuated/inactivated/subunit)vaccines is that they usually elicit cell-mediated immune responses.

Accepted Answer

The answer of An advantage of (attenuated/inactivated/subunit)vaccines is that they...

Question 3

A(n)________ vaccine to prevent cervical cancer was recently developed.

Accepted Answer

A)  attenuated 
B)  combination 
C)  inactivated whole 
D)  recombinant 
E)  toxoid 
A)  attenuated 
B)  combination 
C)  inactivated whole 
D)  recombinant 
E)  toxoid

Question 4

a person who has been exposed to rabies receives both HRIG (human rabies immunoglobulin)injected near the bite site and the rabies vaccine.What does this strategy represent?

Accepted Answer

A)  active immunization 
B)  passive immunotherapy 
C)  viral hemagglutination inhibition 
D)  passive immunotherapy combined with viral hemagglutination inhibition 
E)  active immunization combined with passive immunotherapy 
A)  active immunization 
B)  passive immunotherapy 
C)  viral hemagglutination inhibition 
D)  passive immunotherapy combined with viral hemagglutination inhibition 
E)  active immunization combined with passive immunotherapy

Question 5

Which of the following diagnostic procedures depends on precipitation of antigen-antibody complexes?

Accepted Answer

A)  blood typing 
B)  immunodiffusion 
C)  viral hemagglutination inhibition tests used to diagnose viral infections 
D)  ELISA 
E)  fluorescent antibody tests 
A)  blood typing 
B)  immunodiffusion 
C)  viral hemagglutination inhibition tests used to diagnose viral infections 
D)  ELISA 
E)  fluorescent antibody tests

Question 6

What type of vaccine is the hepatitis B vaccine?

Accepted Answer

A)  inactivated whole pathogen 
B)  attenuated vaccine 
C)  toxoid vaccine 
D)  a recombinant vaccine composed of a single antigen of the hepatitis virus 
E)  a vaccine produced by treating the virus with formaldehyde 
A)  inactivated whole pathogen 
B)  attenuated vaccine 
C)  toxoid vaccine 
D)  a recombinant vaccine composed of a single antigen of the hepatitis virus 
E)  a vaccine produced by treating the virus with formaldehyde

Question 7

The assay represented in Figure is used to

Accepted Answer

A)  detect antigen-specific antibodies in patient serum. 
B)  detect specific antigen in patient serum. 
C)  determine the titer of IgM in patient serum. 
D)  determine the presence of an antibody-modifying enzyme in a patient sample. 
E)  detect cytopathic effects of viral infection. 
A)  detect antigen-specific antibodies in patient serum. 
B)  detect specific antigen in patient serum. 
C)  determine the titer of IgM in patient serum. 
D)  determine the presence of an antibody-modifying enzyme in a patient sample. 
E)  detect cytopathic effects of viral infection.

Question 8

An (ELISA/immunofiltration/immunoblot)assay uses antibodies bound on the surface of a membrane filter to detect antigens.

Accepted Answer

The answer of An (ELISA/immunofiltration/immunoblot)assay uses antibodies bound on the...

Question 9

Anti-antibodies are used in indirect antibody assays.

Accepted Answer

A) True 
 B)False

Question 10

The virulence of the rabies virus is increased by prolonged culture in rabbit spinal cells.

Accepted Answer

A) True 
 B)False

Question 11

Which property of antibodies is the basis for complement fixation tests?

Accepted Answer

A)  agglutination 
B)  opsonization 
C)  neutralization 
D)  direct killing 
E)  complement activation 
A)  agglutination 
B)  opsonization 
C)  neutralization 
D)  direct killing 
E)  complement activation

Question 12

How has modern technology helped to produce new types of vaccines?

Accepted Answer

Scientists have used a variety of recomb

Question 13

A woman uses a home pregnancy test kit that tests for hCG hormone in urine.She knows this is a type of antibody assay from the kit brochure.Antibodies reacting with the hormone produce two lines on the test strip.What specific type of antibody assay does this represent?

Accepted Answer

A)  a direct immunofluoresence test 
B)  a complement fixation test 
C)  an immunochromatographic assay 
D)  an ELISA 
E)  a neutralization assay 
A)  a direct immunofluoresence test 
B)  a complement fixation test 
C)  an immunochromatographic assay 
D)  an ELISA 
E)  a neutralization assay

Question 14

When immunization levels in a population are high,________ provides protection from infection for at-risk persons who cannot be immunized.

Accepted Answer

A)  contact immunity 
B)  active immunization 
C)  herd immunity 
D)  adjuvant therapy 
E)  variolation 
A)  contact immunity 
B)  active immunization 
C)  herd immunity 
D)  adjuvant therapy 
E)  variolation

Question 15

A new virus is discovered that causes cells to lyse.Which of the following types of assay would be useful for diagnosing infection with this virus?

Accepted Answer

A)  agglutination 
B)  complement fixation test 
C)  viral hemagglutination 
D)  both agglutination and complement fixation tests 
E)  viral neutralization 
A)  agglutination 
B)  complement fixation test 
C)  viral hemagglutination 
D)  both agglutination and complement fixation tests 
E)  viral neutralization

Question 16

For some bacterial diseases such as tetanus,it is more effective to produce an immune response against the bacterial toxin than against the bacteria.

Accepted Answer

A) True 
 B)False

Question 17

The MMR (measles,mumps,rubella)vaccine requires multiple immunizations in the first year because it is composed of whole killed viruses.

Accepted Answer

A) True 
 B)False

Question 18

Raising viruses for numerous generations can produce an (adjuvant/attenuated/inactivated)form of the virus.

Accepted Answer

The answer of Raising viruses for numerous generations can produce...

Question 19

Antivenin is a(n)

Accepted Answer

A)  antitoxin used to treat snakebites. 
B)  antigen produced from a virus. 
C)  antiserum produced from hybridomas. 
D)  vaccine made toward the endotoxin of a virus. 
E)  vaccine produced against the endotoxin of a bacterium. 
A)  antitoxin used to treat snakebites. 
B)  antigen produced from a virus. 
C)  antiserum produced from hybridomas. 
D)  vaccine made toward the endotoxin of a virus. 
E)  vaccine produced against the endotoxin of a bacterium.

Question 20

The first true vaccine provided immunity to

Accepted Answer

A)  anthrax. 
B)  cholera. 
C)  pertussis. 
D)  rabies. 
E)  smallpox. 
A)  anthrax. 
B)  cholera. 
C)  pertussis. 
D)  rabies. 
E)  smallpox.

Exam 17: Immunization and Immune Testing

Almost a century after Edward Jenner introduced successful vaccination,Louis Pasteur developed vaccine(s)against

An advantage of (attenuated/inactivated/subunit)vaccines is that they usually elicit cell-mediated immune responses.

A(n)________ vaccine to prevent cervical cancer was recently developed.

a person who has been exposed to rabies receives both HRIG (human rabies immunoglobulin)injected near the bite site and the rabies vaccine.What does this strategy represent?

Which of the following diagnostic procedures depends on precipitation of antigen-antibody complexes?

What type of vaccine is the hepatitis B vaccine?

The assay represented in Figure is used to

An (ELISA/immunofiltration/immunoblot)assay uses antibodies bound on the surface of a membrane filter to detect antigens.

Anti-antibodies are used in indirect antibody assays.

The virulence of the rabies virus is increased by prolonged culture in rabbit spinal cells.

Which property of antibodies is the basis for complement fixation tests?

How has modern technology helped to produce new types of vaccines?

A woman uses a home pregnancy test kit that tests for hCG hormone in urine.She knows this is a type of antibody assay from the kit brochure.Antibodies reacting with the hormone produce two lines on the test strip.What specific type of antibody assay does this represent?

When immunization levels in a population are high,________ provides protection from infection for at-risk persons who cannot be immunized.

A new virus is discovered that causes cells to lyse.Which of the following types of assay would be useful for diagnosing infection with this virus?

For some bacterial diseases such as tetanus,it is more effective to produce an immune response against the bacterial toxin than against the bacteria.

The MMR (measles,mumps,rubella)vaccine requires multiple immunizations in the first year because it is composed of whole killed viruses.

Raising viruses for numerous generations can produce an (adjuvant/attenuated/inactivated)form of the virus.

Antivenin is a(n)

The first true vaccine provided immunity to

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