Question 1

The acetylcholinesterase at the neuromuscular junction is located in the

Accepted Answer

A)  Muscle mem brane 
B)  Basement membrane 
C)  Pre-synaptic mem brane 
D)  Synaptic vesicles 
E)  Synaptic mitochondria 
A)  Muscle mem brane 
B)  Basement membrane 
C)  Pre-synaptic mem brane 
D)  Synaptic vesicles 
E)  Synaptic mitochondria

Question 2

A neurotransmitter released onto a motor neuron opens a Cl- channel. This typically causes

Accepted Answer

A)  An IPSP 
B)  An EPSP 
C)  A MEPP 
D)  An action potential 
E)  An EPP 
A)  An IPSP 
B)  An EPSP 
C)  A MEPP 
D)  An action potential 
E)  An EPP

Question 3

Wave summation and tetany of muscle contraction is caused by

Accepted Answer

A)  Spatial integration of the Ca2+ transients 
B)  Compression of the series elastic elem ents 
C)  Electrotonic spread of the end plate potential 
D)  Summation of miniature end plate potentials 
E)  Release of Ca2+ from the SR before the Ca2+ transient has returned to baseline 
A)  Spatial integration of the Ca2+ transients 
B)  Compression of the series elastic elem ents 
C)  Electrotonic spread of the end plate potential 
D)  Summation of miniature end plate potentials 
E)  Release of Ca2+ from the SR before the Ca2+ transient has returned to baseline

Question 4

The final intracellular activator of skeletal muscle contraction is

Accepted Answer

A)  Phosphorylation of the myosin light chains 
B)  The muscle membrane action potential 
C)  Ca2+ influx through voltage-dependent Ca2+ channels 
D)  Ca2+ released through the ryanodine receptors from the SR 
E)  Inositol trisphosphate 
A)  Phosphorylation of the myosin light chains 
B)  The muscle membrane action potential 
C)  Ca2+ influx through voltage-dependent Ca2+ channels 
D)  Ca2+ released through the ryanodine receptors from the SR 
E)  Inositol trisphosphate

Question 5

The most common cause of myasthenia gravis is

Accepted Answer

A)  Excess acetylcholinesterase 
B)  Failure of vesicle fusion on the presynaptic neuronal mem brane 
C)  Increased diffusion distance to the muscle mem brane 
D)  Autoimmune destruction of the acetylcholine receptor 
E)  Poisoning by curare 
A)  Excess acetylcholinesterase 
B)  Failure of vesicle fusion on the presynaptic neuronal mem brane 
C)  Increased diffusion distance to the muscle mem brane 
D)  Autoimmune destruction of the acetylcholine receptor 
E)  Poisoning by curare

Exam 22: Neuromuscular Junction and Ec Coupling

The acetylcholinesterase at the neuromuscular junction is located in the

A neurotransmitter released onto a motor neuron opens a Cl- channel. This typically causes

Wave summation and tetany of muscle contraction is caused by

The final intracellular activator of skeletal muscle contraction is

The most common cause of myasthenia gravis is

Physical Foundations Ii: Electrical Force Potential Capacitance and Current

Chemical Foundations I: Chemical Energy and Intermolecular Forces

Chemical Foundations Ii: Concentration and Kinetics

Diffusion

Electrochemical Potential and Free Energy

Cell Structure

Dna and Protein Synthesis

Protein Structure

Biological Membranes

Passive Transport and Facilitated Diffusion

Active Transport: Pumps and Exchangers

Osmosis and Osmotic Pressure

Cell Signaling

ATP Production I: Glycolysis

Atp Production Ii: Tca Cycle and Oxidative Phosphorylation

Atp Production Iii: Fatty Acid Oxidation and Amino Acid Oxidation

Origin of the Membrane Potential

The Action Potential

Propagation of the Action Potential

Skeletal Muscle Mechanics

Contractile Mechanisms in Skeletal Muscle

Muscle Energetics Fatigue and Training

Smooth Muscle

Organization of the Nervous System

Cells Synapses and Neurotransmitters

Cutaneous Sensory Systems

Spinal Reflexes

Balance and Control of Movement

the Chemical Senses

Hearing

Vision

Autonomic Nervous System

Overview of the Cv System and Blood

Plasma and Red Blood Cells

White Blood Cells and Inflammation

The Heart As a Pump

Cellular Basis of Cardiac Contractility

the Cardiac Function Curve

Vascular Function: Hemodynamics

Microcirculation and Solute Exchange

Regulation of Perfusion

Integration of Cardiac Output and Venous Return

Regulation of Arterial Pressure

Mechanics of Breathing

Lung Volumes and Airway Resistance

Gas Exchange in the Lung

Oxygen and Carbon Dioxide Transport

Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation

Control of Ventilation

Anatomy and Renal Overview

Glomerular Filtration

Tubular Reabsorption and Secretion

Concentration and Dilution of Urine

Mouth and Esophagus

The Stomach

Intestinal and Colonic Motility

Pancreatic and Biliary Secretion

Digestion and Absorption of the Macronutrients

Energy Balance and Regulation of Food Intake

General Principles of Endocrinology

Hypothalamus and Pituitary Gland

The Thyroid Gland

The Endocrine Pancreas

The Adrenal Cortex

The Adrenal Medulla

The Calcitropic Hormones

Calcium and Phosphorus Homeostasis Ii

Female Reproductive Physiology

Filters

A neurotransmitter released onto a motor neuron opens a Cl^- channel. This typically causes