Exam 12: Microbial Genomics

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Explain why large- genome organisms might be strongly selected for in a soil habitat.

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Genome sequencing is an expensive endeavor, so the needs of the biomedical and biotechnology industries are important drivers for selecting genomes to be sequenced.

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When comparing genes from Archaea, Bacteria, and Eukarya, which statement is TRUE?

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It is generally accepted that independent mutation rather than gene duplication is the mechanism for evolution of most new genes.

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The three mechanisms for horizontal gene transfer in prokaryotes are __________ ,_________ , and _________.

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Microarrays allow for

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Comparative genomics helps us to understand evolutionary relationships between organisms.

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The first DNA genome to be sequenced was that of the ssDNA virus 0X174 and debuted the

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Bioinformatics is a field of study that_________ .

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The science that applies powerful computational tools to DNA and protein sequences for the purpose of analyzing, storing, and accessing the sequences for comparative purposes is known as

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Explain the terms "core genome" and "pan genome" and describe how each contributes to the genome of a bacterial species.

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Special proteins or other molecules or structures necessary to cause disease are known as_________.

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The total genetic complement of all cells within a microbial community is called a(n)

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Most integrons are found on _________or in _________and may collect multiple_________ .

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The number of genes whose role can clearly be identified in a given genome is_________ or less of the total number of ORFs detected.

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Gene sequencing requires high- throughput sequencing as well as powerful computational capacities.

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Explain why organisms undergoing rapid evolutionary change often contain relatively large numbers of mobile DNA elements, whereas once organisms settle into a stable evolutionary niche, most of these mobile elements are lost.

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The study of the structure, function, and regulation of all the proteins present in an organism is called_________ .

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Chromosomal islands are presumed to have a "foreign" origin based upon three observations. What are these observations and how do they indicate that chromosomal islands are "foreign" in origin?

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Explain why the words "about" and "approximately" are used in discussing certain genomes that have been fully sequenced.

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