The reaction, 2 NH4+ + α-ketoglutarate + NADPH + ATP → glutamine + NADP+ + ADP + Pi + H2O, is the combined result of what two enzymes?

A) nitrogenase and glutamate dehydrogenase (GDH) B) GDH and glutamine synthetase (GS) C) GS and nitrogenase D) GDH and nitrogenase E) all of these are correct A) nitrogenase and glutamate dehydrogenase (GDH) B) GDH and glutamine synthetase (GS) C) GS and nitrogenase D) GDH and nitrogenase E) all of these are correct

Exam 20: Amino Acid Metabolism

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Suppose that the formation of a dipeptide is endergonic by +14.7 kJ/mol. If this reaction is coupled with the hydrolysis of ATP, will the net reaction be spontaneous or nonspontaneous? Explain your answer.

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Question 1

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The net reaction will be spontaneous since the ΔG_net value is −15.8 kJ/mol. This is based on coupling the endergonic reaction with a ΔG of +14.7 kJ/mol with the exergonic hydrolysis of ATP with a ΔG value of −30.5 kJ/mol. ΔG_net = −30.5 kJ/mol +14.7 kJ/mol = −15.8 kJ/mol.

This many ATP equivalents are required to produce one molecule of urea from ammonia:

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Question 2

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Write a mechanism for the nonenzymatic transformation of glutamate semialdehyde into 1-pyrroline-5-carboxylate. Which amino acid is synthesized from 1-pyrroline-5-carboxylate in vivo?

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Question 3

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proline is synthesized from 1-pyrroline-5-carboxylate.

3-Phosphoglycerate contains the carbon skeleton used to make

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Question 4

The reaction, 2 NH₄⁺ + α-ketoglutarate + NADPH + ATP → glutamine + NADP⁺ + ADP + P_i + H₂O, is the combined result of what two enzymes?

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Question 5

The coenzyme pyridoxal phosphate (PLP) in its active form has all the following characteristics except:

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Question 6

Consider the deamination of serine to answer the following questions. a)Draw the structure of the α-keto acid produced by the deamination of serine. b)What is the fate of the amino group in serine when this conversion occurs in a mammalian system?

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Question 7

What amino acid is the following α-keto acid derived from?

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Question 8

Ornithine serves three metabolically important roles but is not found in proteins. Which of the following statements about ornithine is not true?

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Question 9

Amino acids biosynthesized from aspartate include all except:

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Question 10

Aspartate is formed from transamination of:

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Question 11

Which of the following is not an intermediate in the urea cycle?

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Question 12

What product would be obtained from enzymatic transamination of 3-hydroxy-2-ketopropanoic acid?

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Question 13

Draw the structure of the product formed when the substance shown below undergoes amide formation.

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Question 14

The key functional group in the PLP-dependent transamination of an α-amino acid is an activated

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Question 15

In the process of amino acid biosynthesis, how are glutamic acid, glutamine, proline, and arginine all related?

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Question 16

Glucogenic amino acids include all of the following, except:

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Question 17

The following shows a part of the biosynthetic pathway of amino acids. If possible, draw an arrow to match the amino acid with its precursor.

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Question 18

The formation of amino acids from proteins

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Question 19

What reaction does glutamate dehydrogenase (GDH) catalyze?

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Question 20

Showing 1 - 20 of 32

Exam 20: Amino Acid Metabolism

Suppose that the formation of a dipeptide is endergonic by +14.7 kJ/mol. If this reaction is coupled with the hydrolysis of ATP, will the net reaction be spontaneous or nonspontaneous? Explain your answer.

This many ATP equivalents are required to produce one molecule of urea from ammonia:

Write a mechanism for the nonenzymatic transformation of glutamate semialdehyde into 1-pyrroline-5-carboxylate. Which amino acid is synthesized from 1-pyrroline-5-carboxylate in vivo?

3-Phosphoglycerate contains the carbon skeleton used to make

The reaction, 2 NH4+ + α-ketoglutarate + NADPH + ATP → glutamine + NADP+ + ADP + Pi + H2O, is the combined result of what two enzymes?

The coenzyme pyridoxal phosphate (PLP) in its active form has all the following characteristics except:

Consider the deamination of serine to answer the following questions. a)Draw the structure of the α-keto acid produced by the deamination of serine. b)What is the fate of the amino group in serine when this conversion occurs in a mammalian system?

What amino acid is the following α-keto acid derived from?

Ornithine serves three metabolically important roles but is not found in proteins. Which of the following statements about ornithine is not true?

Amino acids biosynthesized from aspartate include all except:

Aspartate is formed from transamination of:

Which of the following is not an intermediate in the urea cycle?

What product would be obtained from enzymatic transamination of 3-hydroxy-2-ketopropanoic acid?

Draw the structure of the product formed when the substance shown below undergoes amide formation.

The key functional group in the PLP-dependent transamination of an α-amino acid is an activated

In the process of amino acid biosynthesis, how are glutamic acid, glutamine, proline, and arginine all related?

Glucogenic amino acids include all of the following, except:

The following shows a part of the biosynthetic pathway of amino acids. If possible, draw an arrow to match the amino acid with its precursor.

The formation of amino acids from proteins

What reaction does glutamate dehydrogenase (GDH) catalyze?

Structure and Bonding

Polar Covalent Bonds; Acids and Bases

Organic Compounds: Alkanes and Their Stereochemistry

Organic Compounds: Cycloalkanes and Their Stereochemistry

Stereochemistry at Tetrahedral Centers

An Overview of Organic Reactions

Alkenes and Alkynes

Reactions of Alkenes and Alkynes

Aromatic Compounds

Structure Determination: Mass Spectrometry, Infrared Spectroscopy, and Ultraviolet Spectroscopy

Structure Determination: Mass Spectrometry, Infrared Spectroscopy, and Ultraviolet Spectroscopy

Structure Determination: Nuclear Magnetic Resonance Spectroscopy

Organohalides: Nucleophilic Substitutions and Eliminations

Alcohols, Phenols, and Thiols; Ethers and Sulfides

Aldehydes and Ketones: Nucleophilic Addition Reactions

Carboxylic Acids and Nitriles

Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Carbonyl Alpha-Substitution and Condensation Reactions

Amines and Heterocycles

Biomolecules: Amino Acids, Peptides, and Proteins

Biomolecules: Carbohydrates

Carbohydrate Metabolism

Biomolecules: Lipids and Their Metabolism

Biomolecules: Nucleic Acids and Their Metabolism

Orbitals and Organic Chemistry: Pericyclic Reactionse

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The reaction, 2 NH₄⁺ + α-ketoglutarate + NADPH + ATP → glutamine + NADP⁺ + ADP + P_i + H₂O, is the combined result of what two enzymes?