Question 1

Which of the following can cause enzyme activity to either increase or decrease?

Accepted Answer

A)  increasing the substrate concentration 
B)  changing the pH 
C)  both a and b 
D)  neither a nor b 
A)  increasing the substrate concentration 
B)  changing the pH 
C)  both a and b 
D)  neither a nor b

Question 2

What designations are used to distinguish between the two forms of an allosteric enzyme?

Accepted Answer

A)  α and β 
B)  D and L 
C)  R and S 
D)  R and T 
A)  α and β 
B)  D and L 
C)  R and S 
D)  R and T

Question 3

The names of enzymes are often derived from which of the following?

Accepted Answer

A)  the name of their discoverer 
B)  the compound on which they act 
C)  both a and b 
D)  neither a nor b 
A)  the name of their discoverer 
B)  the compound on which they act 
C)  both a and b 
D)  neither a nor b

Question 4

What term is used to describe a species which affects the functioning of an allosteric enzyme?

Accepted Answer

A)  alloster 
B)  controller 
C)  inhibitor 
D)  regulator 
A)  alloster 
B)  controller 
C)  inhibitor 
D)  regulator

Question 5

Consider the following two images depicting enzyme behavior.     A B Which model explains competitive inhibition?

Accepted Answer

A)  A only 
B)  B only 
C)  Both A and B explain competitive inhibition. 
A)  A only 
B)  B only 
C)  Both A and B explain competitive inhibition.

Question 6

What name is given to the intermediate in an enzyme-catalyzed reaction?

Accepted Answer

A)  apoenzyme 
B)  coenzyme 
C)  enzyme-substrate complete 
D)  zymogen 
A)  apoenzyme 
B)  coenzyme 
C)  enzyme-substrate complete 
D)  zymogen

Question 7

What disease is diagnosed by monitoring amylase activity?

Accepted Answer

A)  hepatitis 
B)  liver cancer 
C)  pancreatic disease 
D)  prostate cancer 
A)  hepatitis 
B)  liver cancer 
C)  pancreatic disease 
D)  prostate cancer

Question 8

Transition-state analogs do which of the following?

Accepted Answer

A)  They assist in the synthesis of specialized enzymes. 
B)  They assist in transporting the substrate to the active site. 
C)  They enhance enzyme activity. 
D)  They inhibit enzyme activity. 
A)  They assist in the synthesis of specialized enzymes. 
B)  They assist in transporting the substrate to the active site. 
C)  They enhance enzyme activity. 
D)  They inhibit enzyme activity.

Question 9

Consider the following image depicting enzyme regulation for a two subunit enzyme.   Which of the following is correct?

Accepted Answer

A)  The R0 state interacts with the substrate. 
B)  The R0 state interacts with the activator. 
C)  The T0 state interacts with the inhibitor. 
D)  All of these are correct. 
E)  None of these are correct. 
A)  The R0 state interacts with the substrate. 
B)  The R0 state interacts with the activator. 
C)  The T0 state interacts with the inhibitor. 
D)  All of these are correct. 
E)  None of these are correct.

Question 10

Which of the following is another name for a proenzyme?

Accepted Answer

A)  allosteric enzyme 
B)  coenzyme 
C)  cofactor 
D)  zymogen 
A)  allosteric enzyme 
B)  coenzyme 
C)  cofactor 
D)  zymogen

Question 11

In which type of inhibition is it not possible to restore the maximum rate of enzyme activity by adding additional substrate?

Accepted Answer

A)  cooperative inhibition 
B)  competitive inhibition 
C)  noncompetitive inhibition 
D)  selective inhibition 
A)  cooperative inhibition 
B)  competitive inhibition 
C)  noncompetitive inhibition 
D)  selective inhibition

Question 12

What name is given to the molecule on which the enzyme works?

Accepted Answer

A)  cofactor 
B)  isozyme 
C)  substrate 
D)  zymogen 
A)  cofactor 
B)  isozyme 
C)  substrate 
D)  zymogen

Question 13

Which of the following is true of all allosteric enzymes?

Accepted Answer

A)  They consist of proteins only. 
B)  They have a nonprotein portion. 
C)  They have more than one active site on each subunit. 
D)  Binding at one site affects protein function at a second site. 
A)  They consist of proteins only. 
B)  They have a nonprotein portion. 
C)  They have more than one active site on each subunit. 
D)  Binding at one site affects protein function at a second site.

Question 14

An abzyme is which of the following?

Accepted Answer

A)  an abnormal enzyme 
B)  an antibody with catalytic ability 
C)  an antigen with catalytic ability 
D)  an immunogen 
A)  an abnormal enzyme 
B)  an antibody with catalytic ability 
C)  an antigen with catalytic ability 
D)  an immunogen

Question 15

Consider the following two images depicting enzyme behavior.     A B Which model provides a better explanation of noncompetitive inhibition?

Accepted Answer

A)  A only 
B)  B only 
C)  Both A and B provide equally good explanations. 
A)  A only 
B)  B only 
C)  Both A and B provide equally good explanations.

Question 16

What is an apoenzyme?

Accepted Answer

A)  an enzyme made entirely of protein 
B)  the nonprotein part of an enzyme 
C)  the protein only part of an enzyme 
D)  the inactive form of an enzyme 
A)  an enzyme made entirely of protein 
B)  the nonprotein part of an enzyme 
C)  the protein only part of an enzyme 
D)  the inactive form of an enzyme

Question 17

Which of the following is true of trypsin?

Accepted Answer

A)  It does not affect any peptide bonds. 
B)  It hydrolyzes all peptide bonds. 
C)  It hydrolyzes peptide bonds to leucine and phenylalanine. 
D)  It hydrolyzes peptide bonds to arginine and lysine. 
A)  It does not affect any peptide bonds. 
B)  It hydrolyzes all peptide bonds. 
C)  It hydrolyzes peptide bonds to leucine and phenylalanine. 
D)  It hydrolyzes peptide bonds to arginine and lysine.

Question 18

Which of the following is associated with noncompetitive inhibition?

Accepted Answer

A)  allosterism 
B)  allotropism 
C)  isomerization 
D)  racemization 
A)  allosterism 
B)  allotropism 
C)  isomerization 
D)  racemization

Question 19

The names of enzymes are often derived from which of the following?

Accepted Answer

A)  the reaction they catalyze 
B)  the compound on which they act 
C)  both a and b 
D)  neither a nor b 
A)  the reaction they catalyze 
B)  the compound on which they act 
C)  both a and b 
D)  neither a nor b

Question 20

Which of the following are monitored to diagnose the severity of a heart attack?

Accepted Answer

A)  AST 
B)  CPK 
C)  LDH 
D)  all of these 
A)  AST 
B)  CPK 
C)  LDH 
D)  all of these

Exam 23: Enzymes

Which of the following can cause enzyme activity to either increase or decrease?

What designations are used to distinguish between the two forms of an allosteric enzyme?

The names of enzymes are often derived from which of the following?

What term is used to describe a species which affects the functioning of an allosteric enzyme?

Consider the following two images depicting enzyme behavior. A B Which model explains competitive inhibition?

What name is given to the intermediate in an enzyme-catalyzed reaction?

What disease is diagnosed by monitoring amylase activity?

Transition-state analogs do which of the following?

Consider the following image depicting enzyme regulation for a two subunit enzyme. Which of the following is correct?

Which of the following is another name for a proenzyme?

In which type of inhibition is it not possible to restore the maximum rate of enzyme activity by adding additional substrate?

What name is given to the molecule on which the enzyme works?

Which of the following is true of all allosteric enzymes?

An abzyme is which of the following?

Consider the following two images depicting enzyme behavior. A B Which model provides a better explanation of noncompetitive inhibition?

What is an apoenzyme?

Which of the following is true of trypsin?

Which of the following is associated with noncompetitive inhibition?

The names of enzymes are often derived from which of the following?

Which of the following are monitored to diagnose the severity of a heart attack?

Matter, Energy, and Measurement

Atoms

Chemical Bonds

Chemical Reactions

Gases, Liquids, and Solids

Solutions and Colloids

Reaction Rates and Chemical Equilibrium

Acids and Bases

Nuclear Chemistry

Organic Chemistry

Alkanes

Alkenes and Alkynes

Benzene and Its Derivatives

Alcohols, Ethers, and Thiols

Chirality: the Handedness of Molecules

Amines

Aldehydes and Ketones

Carboxylic Acids

Carboxylic Anhydrides, Esters, and Amides

Carbohydrates

Lipids

Proteins

Chemical Communications: Neurotransmitters and Hormones

Nucleotides, Nucleic Acids, and Heredity

Gene Expression and Protein Synthesis

Bioenergetics: How the Body Converts Food to Energy

Specific Catabolic Pathways: Carbohydrate, Lipid, and Protein Metabolism

Biosynthetic Pathways

Nutrition

Immunochemistry

Body Fluids

Filters