Question 1

Which of the following is true of TATA boxes?

Accepted Answer

A)  they are found within the core sequence of a gene regulatory sequence 
B)  they are found downstream of the gene being transcribed 
C)  they represent an area of DNA more easily opened than other areas 
D)  a and c are true 
E)  a, b, and c are true 
A)  they are found within the core sequence of a gene regulatory sequence 
B)  they are found downstream of the gene being transcribed 
C)  they represent an area of DNA more easily opened than other areas 
D)  a and c are true 
E)  a, b, and c are true

Question 2

During RNA chain elongation, ____ proceeds ahead of the transcription bubble introducing _____ supercoils

Accepted Answer

A)  gyrase; negative 
B)  gyrase; positive 
C)  topoisomerase; negative 
D)  topoisomerase; positive 
E)  none of the above 
A)  gyrase; negative 
B)  gyrase; positive 
C)  topoisomerase; negative 
D)  topoisomerase; positive 
E)  none of the above

Question 3

Explain the functions of the transcription factors that are a part of the eukaryotic preinitiation complex (PIC).​

Accepted Answer

​The PIC consists of RNA polymerase II a

Question 4

Nucleotide sequences that identify the location of transcription start sites and regulate the level of transcription are called:

Accepted Answer

A)  sigma factors. 
B)  Pribnow boxes. 
C)  TATA boxes. 
D)  promoters. 
E)  enhancers. 
A)  sigma factors. 
B)  Pribnow boxes. 
C)  TATA boxes. 
D)  promoters. 
E)  enhancers.

Question 5

Which of the following is true of the lac operon?

Accepted Answer

A)  it is negatively controlled via the lac repressor, a protein that only binds to DNA in the absence of lactose 
B)  it is positively controlled via CAP, a protein that is activated by binding to ATP 
C)  lactose represses the lac operon but this repression can be removed by addition of IPTG 
D)  binding of lactose (or an analog of lactose) increases the affinity of the lac repressor for DNA 
E)  none of the above 
A)  it is negatively controlled via the lac repressor, a protein that only binds to DNA in the absence of lactose 
B)  it is positively controlled via CAP, a protein that is activated by binding to ATP 
C)  lactose represses the lac operon but this repression can be removed by addition of IPTG 
D)  binding of lactose (or an analog of lactose) increases the affinity of the lac repressor for DNA 
E)  none of the above

Question 6

One of the termination mechanisms in bacteria utilizes the ____ factor that is an ATP-dependent helicase.

Accepted Answer

A)  α (alpha) 
B)  β (beta) 
C)  γ (gamma) 
D)  ε (delta) 
E)  ρ (rho) 
A)  α (alpha) 
B)  β (beta) 
C)  γ (gamma) 
D)  ε (delta) 
E)  ρ (rho)

Question 7

All are components of the lac operon EXCEPT:

Accepted Answer

A)  the structural genes for lacZ, lacY and lacA. 
B)  the operator and promoter sequences. 
C)  lacI gene. 
D)  promoter for the lacI gene. 
E)  all are correct. 
A)  the structural genes for lacZ, lacY and lacA. 
B)  the operator and promoter sequences. 
C)  lacI gene. 
D)  promoter for the lacI gene. 
E)  all are correct.

Question 8

The subunit in E. coli RNA polymerase which is required for recognition of the promoter sequence is:

Accepted Answer

A)  ρ (rho). 
B)  α (alpha). 
C)  β (beta). 
D)  β′ (beta prime). 
E)  σ (sigma). 
A)  ρ (rho). 
B)  α (alpha). 
C)  β (beta). 
D)  β′ (beta prime). 
E)  σ (sigma).

Which of the following is true of TATA boxes?

During RNA chain elongation, proceeds ahead of the transcription bubble introducing _ supercoils

Explain the functions of the transcription factors that are a part of the eukaryotic preinitiation complex (PIC).

Nucleotide sequences that identify the location of transcription start sites and regulate the level of transcription are called:

Which of the following is true of the lac operon?

One of the termination mechanisms in bacteria utilizes the ____ factor that is an ATP-dependent helicase.

All are components of the lac operon EXCEPT:

The subunit in E. coli RNA polymerase which is required for recognition of the promoter sequence is:

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Filters

Exam 29: Transcription and the Regulation of Gene Expression

Which of the following is true of TATA boxes?

During RNA chain elongation, ____ proceeds ahead of the transcription bubble introducing _____ supercoils

Explain the functions of the transcription factors that are a part of the eukaryotic preinitiation complex (PIC).​

Nucleotide sequences that identify the location of transcription start sites and regulate the level of transcription are called:

Which of the following is true of the lac operon?

One of the termination mechanisms in bacteria utilizes the ____ factor that is an ATP-dependent helicase.

All are components of the lac operon EXCEPT:

The subunit in E. coli RNA polymerase which is required for recognition of the promoter sequence is:

The Facts of Life: Chemistry Is the Logic of Biological Phenomena

Water: the Medium of Life

Thermodynamics of Biological Systems

Amino Acids and the Peptide Bond

Proteins: Their Primary Structure and Biological Functions

Proteins: Secondary, Tertiary, and Quaternary Structure

Carbohydrates and the Glycoconjugates of Cell Surfaces

Lipids

Membranes and Membrane Transport

Nucleotides and Nucleic Acids

Structure of Nucleic Acids

Recombinant Dna, Cloning, Chimeric Genes, and Synthetic Biology

Enzymeskinetics and Specificity

Mechanisms of Enzyme Action

Enzyme Regulation

Molecular Motors

Metabolism: an Overview

Glycolysis

The Tricarboxylic Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Fatty Acid Catabolism

Lipid Biosynthesis

Nitrogen Acquisition and Amino Acid Metabolism

Synthesis and Degradation of Nucleotides

Metabolic Integration and Organ Specialization

Dna Metabolism: Replication, Recombination, and Repair

Protein Synthesis

Completing the Protein Life Cycle: Folding, Processing, and Degradation

The Reception and Transmission of Extracellular Information

Filters

During RNA chain elongation, proceeds ahead of the transcription bubble introducing _ supercoils

Explain the functions of the transcription factors that are a part of the eukaryotic preinitiation complex (PIC).