Question 1

Would a weak or a strong promotor be more active in a prokaryotic cell? Explain your answer.

Accepted Answer

It may depend on the organism

Question 2

A common RNA base modification is

Accepted Answer

A)  methylation. 
B)  amination. 
C)  carboxylation. 
D)  hydroxylation. 
A)  methylation. 
B)  amination. 
C)  carboxylation. 
D)  hydroxylation.

Question 3

Which RNA molecule is expressed in the genome to regulate gene expression?

Accepted Answer

A)  RNAi 
B)  snoRNA 
C)  miRNA 
D)  siRNA 
A)  RNAi 
B)  snoRNA 
C)  miRNA 
D)  siRNA

Question 4

Eukaryotic transcription promoters

Accepted Answer

A)  are typically found after the transcription start site. 
B)  have a single sequence and bind one RNA polymerase type. 
C)  may bind to both transcription factors and RNA polymerases. 
D)  are all controlled by a ubiquitous  Factor. 
A)  are typically found after the transcription start site. 
B)  have a single sequence and bind one RNA polymerase type. 
C)  may bind to both transcription factors and RNA polymerases. 
D)  are all controlled by a ubiquitous  Factor.

Question 5

What do   factors bind to in RNA synthesis?

Accepted Answer

A)  DNA promoters and RNA polymerase 
B)  RNA promoters and DNA 
C)  DNA and RNA 
D)  transcription factors 
A)  DNA promoters and RNA polymerase 
B)  RNA promoters and DNA 
C)  DNA and RNA 
D)  transcription factors

Question 6

Draw a double-stranded piece of DNA,label the   and   ends,and show which strand is transcribed and in which direction.

Accepted Answer

The answer of Draw a double-stranded piece of DNA,label the...

Question 7

Name the RNA molecules involved in protein expression and synthesis that are found in both prokaryotic and eukaryotic organisms,and name the RNA molecules involved in protein expression and synthesis only in eukaryotic organisms.

Accepted Answer

(1)rRNA,(2)tRNA,and (3)mRNA are found in

Question 8

RNA is a dynamic biomolecule because it can

Accepted Answer

A)  be a component in protein synthesis, regulate protein synthesis, and be synthesized and function in cell nucleus. 
B)  catalyze its own synthesis. 
C)  contain a ribose sugar backbone. 
D)  be stable to hydrolysis. 
A)  be a component in protein synthesis, regulate protein synthesis, and be synthesized and function in cell nucleus. 
B)  catalyze its own synthesis. 
C)  contain a ribose sugar backbone. 
D)  be stable to hydrolysis.

Question 9

RNA is a highly dynamic biomolecule in that it

Accepted Answer

A)  can fold and hydrogen bond with itself, DNA, proteins, or small molecules to adopt largely modified tertiary structures. 
B)  is less capable of forming stable H-bonds than DNA. 
C)  is often shorter than DNA. 
D)  is largely composed of a phosphate backbone. 
A)  can fold and hydrogen bond with itself, DNA, proteins, or small molecules to adopt largely modified tertiary structures. 
B)  is less capable of forming stable H-bonds than DNA. 
C)  is often shorter than DNA. 
D)  is largely composed of a phosphate backbone.

Question 10

Explain why RNAi requires some double-stranded RNA to initiate the process.

Accepted Answer

The enzyme called dicer will c

Question 11

RNA is typically more susceptible to backbone hydrolysis than DNA because of the

Accepted Answer

A)  presence of simpler nucleotides. 
B)  presence of a   OH group. 
C)  presence of a   OH group. 
D)  lack of thymine nucleotides. 
A)  presence of simpler nucleotides. 
B)  presence of a   OH group. 
C)  presence of a   OH group. 
D)  lack of thymine nucleotides.

Question 12

Identify the location of action of the spliceosome.

Accepted Answer

A)  nuclear pore 
B)  nucleus 
C)  rough endoplasmic reticulum 
D)  cytoplasm 
A)  nuclear pore 
B)  nucleus 
C)  rough endoplasmic reticulum 
D)  cytoplasm

Question 13

Which RNA molecule does NOT bind to the ribosome?

Accepted Answer

A)  tRNA 
B)  rRNA 
C)  mRNA 
D)  snRNA 
A)  tRNA 
B)  rRNA 
C)  mRNA 
D)  snRNA

Question 14

It has been estimated that as much as __________ % of the human genome is transcribed into noncoding RNA,whereas __________ % of the E.coli genome is noncoding RNA.

Accepted Answer

A)  10; 90 
B)  90; 10 
C)  50; 10 
D)  25; 2 
A)  10; 90 
B)  90; 10 
C)  50; 10 
D)  25; 2

Question 15

The function of DNase I is that it

Accepted Answer

A)  cuts DNA whenever DNA binding proteins are present. 
B)  cuts double-stranded DNA by cutting phosphodiester bonds. 
C)  cuts DNA binding proteins. 
D)  makes an RNA copy of DNA. 
A)  cuts DNA whenever DNA binding proteins are present. 
B)  cuts double-stranded DNA by cutting phosphodiester bonds. 
C)  cuts DNA binding proteins. 
D)  makes an RNA copy of DNA.

Question 16

What RNA types are required for eukaryotic rRNA and mRNA processing? Where does this processing occur?

Accepted Answer

Small nucleolar RNA (snoRNA)is

Question 17

How are RNA structures different from protein structures?

Accepted Answer

A)  RNA is single stranded, whereas proteins are not. 
B)  RNA can H-bond with itself, whereas proteins cannot. 
C)  RNA mutations can lead to nonfunctioning proteins, whereas protein mutations do not. 
D)  RNA adopts less defined tertiary structures than proteins. 
A)  RNA is single stranded, whereas proteins are not. 
B)  RNA can H-bond with itself, whereas proteins cannot. 
C)  RNA mutations can lead to nonfunctioning proteins, whereas protein mutations do not. 
D)  RNA adopts less defined tertiary structures than proteins.

Question 18

At what point during transcription does the   factor dissociate from the RNA polymerase?

Accepted Answer

A)  in the initiation phase 
B)  in the termination phase 
C)  before the elongation phase 
D)  during the elongation phase 
A)  in the initiation phase 
B)  in the termination phase 
C)  before the elongation phase 
D)  during the elongation phase

Question 19

Which is central to the addition of the 7-methylguanosine cap to mRNA?

Accepted Answer

A)  RNA polymerase 1 
B)  guanine-N7 methyltransferase 
C)  GMP 
D)  snoRNA 
A)  RNA polymerase 1 
B)  guanine-N7 methyltransferase 
C)  GMP 
D)  snoRNA

Question 20

In the following RNAi scheme,label the mRNA,siRNA,RISC,dicer,and double-stranded RNA.

Accepted Answer

The answer of In the following RNAi scheme,label the mRNA,siRNA,RISC,dicer,and...

Exam 21: Rna Synthesis, processing, and Gene Silencing

Would a weak or a strong promotor be more active in a prokaryotic cell? Explain your answer.

A common RNA base modification is

Which RNA molecule is expressed in the genome to regulate gene expression?

Eukaryotic transcription promoters

What do factors bind to in RNA synthesis?

Draw a double-stranded piece of DNA,label the and ends,and show which strand is transcribed and in which direction.

Name the RNA molecules involved in protein expression and synthesis that are found in both prokaryotic and eukaryotic organisms,and name the RNA molecules involved in protein expression and synthesis only in eukaryotic organisms.

RNA is a dynamic biomolecule because it can

RNA is a highly dynamic biomolecule in that it

Explain why RNAi requires some double-stranded RNA to initiate the process.

RNA is typically more susceptible to backbone hydrolysis than DNA because of the

Identify the location of action of the spliceosome.

Which RNA molecule does NOT bind to the ribosome?

It has been estimated that as much as __________ % of the human genome is transcribed into noncoding RNA,whereas __________ % of the E.coli genome is noncoding RNA.

The function of DNase I is that it

What RNA types are required for eukaryotic rRNA and mRNA processing? Where does this processing occur?

How are RNA structures different from protein structures?

At what point during transcription does the factor dissociate from the RNA polymerase?

Which is central to the addition of the 7-methylguanosine cap to mRNA?

In the following RNAi scheme,label the mRNA,siRNA,RISC,dicer,and double-stranded RNA.

Principles of Biochemistry

Physical Biochemistry: Energy Conversion,water,and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Oxidative Phosphorylation

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

Dna Replication, repair, and Recombination

Protein Synthesis, posttranslational Modification, and Transport

Gene Regulation

Filters

It has been estimated that as much as % of the human genome is transcribed into noncoding RNA,whereas % of the E.coli genome is noncoding RNA.