Exam 14: Carbohydrate Metabolism

von Gierke disease is a common glycogen storage disease caused by a deficiency in glucose-6-phosphatase.Explain how a deficiency in this gluconeogenesis enzyme leads to glycogen storage issues.

In the glycogenesis pathway,what is the leaving group in the last step where glucose is added to the growing glycogen chain?

Gluconeogenesis would most likely be allosterically activated simultaneously along with which other metabolic process?

What enzyme class in the nonoxidative phase of the pentose phosphate pathway allows for the reaction of ribose-5-phosphate and xylulose-5-phosphate to produce glyceraldehyde-3-phosphate and seduheptulose-7-phosphate?

Which enzyme catalyzes the following reaction?

Fill in the names of the enzymes involved in the important cellular glutathione detoxification system shown below.

Which pathway is opposite to gluconeogenesis?

Which of the following metabolites has carbon atoms that can end up in glucose via the gluconeogenesis pathway in humans?

State how glucagon functions to increase blood glucose levels.

Which enzyme uses cellular NADPH to regenerate reduced glutathione?

Name each of the distinct catalytic activities of the debranching enzyme.

The first two reactions of gluconeogenesis are required to reverse reaction 10 (or the last reaction)of glycolysis.How many ATP equivalents are used by these first two reactions of gluconeogenesis?

The gluconeogenesis reaction shown below is missing some reactants and products.What class of enzyme catalyzes this reaction?

Which of the following molecules would inhibit the regulated steps in gluconeogenesis?

Name the enzymes of the gluconeogenesis pathway that are required to form the unstable phosphoenolpyruvate molecule from pyruvate starting material.

Which hormone slows down glycolysis while stimulating gluconeogenesis through the phosphorylation of phosphofructokinase 2 (PFK2)and fructose-2,6-bisphosphatase?

Which enzyme in the pentose phosphate pathway catalyzes the following reaction?

Which enzyme in the pentose phosphate pathway is regulated to control flux through the pathway?

The Cori cycle

Gluconeogenesis is favored when citrate levels are __________,when AMP levels are __________,and when ATP levels are __________.