Exam 9: Glycolysis: a Paradigm of Metabolic Regulation

In the presence of high concentrations of ADP and F6P,how does the equilibrium shift between the T state and R state of PFK-1? High concentrations of ADP and F6P

Which of the following best defines substrate-level phosphorylation?

In the presence of lactase,lactose is cleaved into the monosaccharides glucose and

The rate limiting step can be defined as a level of enzyme activity that can be regulated to be __________ even when substrate levels are __________.

Which of following is an anomeric pair?

Using glucose metabolism,justify the following statement: Metabolic pathways are highly interdependent and are exquisitely controlled by enzyme activity levels and substrate bioavailability.

Which of the following metabolic conversions is considered to be the major control point of glycolysis?

Describe how the glycolytic pathway provides aerobic energy to the citrate cycle and oxidative phosphorylation.

Glucokinase is a molecular sensor for which molecule?

Compare the structure of an aldose to a ketose.

Predict how oxygen saturation would be affected if an individual has defective hexokinase enzymes.

Which of the following metabolic pathways is only found in plants?

Illustrate how glyceraldehyde-3-P is converted into 1,3-bisphosphoglycerate by glyceraldehyde-3-P dehydrogenase using the appropriate mechanisms.

The enzyme phosphoglycerate mutase operates at ? 0 kJ/mol.That indicates that the reversibility of that reaction

Is the net reaction favorable for the following series of coupled reactions?

How can an unfavorable reaction ( > 0)still occur in a metabolic pathway?

In the reaction A B,if at equilibrium [B] >> [A],what can be said about the directionality of the reaction?

Catabolic pathways are always paired with anabolic pathways.Why?

What is the potential metabolic fate of pyruvate under aerobic conditions?

In the following figure,what is the linkage between the two monosaccharide units and is this a reducing sugar?