Question 1

Which of the following tripeptides is not hydrolyzed by trypsin?

Accepted Answer

A) Glu-Arg-Ser 
B) Arg-Glu-Thr 
C) Glu-Ser-Arg 
D) Lys-Ser-Arg 
A) Glu-Arg-Ser 
B) Arg-Glu-Thr 
C) Glu-Ser-Arg 
D) Lys-Ser-Arg

Question 2

Structure _____ (shown below) will migrate toward the positive electrode in an electrophoresis experiment.

Accepted Answer

The answer of Structure _____ (shown below) will migrate toward...

Question 3

Which of the following amino acids is not chiral?

Accepted Answer

A) leucine 
B) glycine 
C) alanine 
D) proline 
A) leucine 
B) glycine 
C) alanine 
D) proline

Question 4

Which of the following is not a polypeptide?

Accepted Answer

A) L-HIV-1 protease 
B) hemoglobin 
C) myoglobin 
D) glycogen 
A) L-HIV-1 protease 
B) hemoglobin 
C) myoglobin 
D) glycogen

Question 5

What are the products of the reaction of alanine and ninhydrin (shown below)?

Accepted Answer

The answer of What are the products of the reaction...

Question 6

Consider the following form of phenylalanine.   This form would exist at a pH _______than the pI.

Accepted Answer

The answer of Consider the following form of phenylalanine. ...

Question 7

Hydrogen bonds, $\alpha$-helices, and pleated sheets are properties of structure of proteins.

Accepted Answer

The answer of Hydrogen bonds, $\alpha$-helices, and pleated sheets are...

Question 8

In Phe-Ile-Ser-Asp-Gly-His-Gly-Tyr, the three-letter abbreviation for the C-terminal amino acid is ________.

Accepted Answer

The answer of In Phe-Ile-Ser-Asp-Gly-His-Gly-Tyr, the three-letter abbreviation for the...

Question 9

MATCH a structure from the list below to each of the following terms. Place the letter of the structure in the blank to the left of the term which it describes.
-_____ is an octapeptide with a C-terminal valine.

Accepted Answer

A)   
B)   
C)   
D)   
E)  
F) 
G)BOC group
H) 
I) 
J) 
K) 
L) 
M)Z group 
A)   
B)   
C)   
D)   
E)  
F) 
G)BOC group
H) 
I) 
J) 
K) 
L) 
M)Z group

Question 10

What fragments are produced when porcine dynorphin, a peptide that contains 17 amino acid residues (shown below), is cleaved with trypsin?

Accepted Answer

The answer of What fragments are produced when porcine dynorphin,...

Question 11

Which of the following amino acids migrates to the positive electrode on paper electrophoresis at a pH of 7.0?

Accepted Answer

A) glutamic acid 
B) arginine 
C) lysine 
D) histadine 
A) glutamic acid 
B) arginine 
C) lysine 
D) histadine

Question 12

In the Edman degradation analysis of the N-terminus of a peptide the terminal residue reacts with phenyl isocyanate, an example is shown below. Provide the structure of both of the products of this reaction.

Accepted Answer

The answer of In the Edman degradation analysis of the...

Question 13

The Edman degradation is used to identify the ___-terminal amino acid of a peptide.

Accepted Answer

The answer of The Edman degradation is used to identify...

Question 14

What is the major organic product of the following reaction?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 15

Which of the following amino acids contains two stereocenters?

Accepted Answer

A) isoleucine 
B) proline 
C) phenylalanine 
D) glutamine 
A) isoleucine 
B) proline 
C) phenylalanine 
D) glutamine

Question 16

Which of the following reagents can be used to cleave a benzyloxycarbonyl protecting group from a peptide?

Accepted Answer

A) H2/Pd 
B) H2O 
C) Na2CO3, H2O 
D) LiAlH4 
A) H2/Pd 
B) H2O 
C) Na2CO3, H2O 
D) LiAlH4

Question 17

Which of the following amino acids is not an L-isomer?

Accepted Answer

A) serine 
B) valine 
C) glycine 
D) proline 
A) serine 
B) valine 
C) glycine 
D) proline

Question 18

The number of different combinations that are possible for a tripeptide containing one of each of the following amino acids: Phe, Val, Asp is ______.

Accepted Answer

The answer of The number of different combinations that are...

Question 19

What is the isoelectric point of serine (pKa of $\alpha$-CO2H, 2.21; pKa of $\alpha$-NH2, 9.15)?

Accepted Answer

A) 5.68 
B) 9.94 
C) 11.36 
D) 20.22 
A) 5.68 
B) 9.94 
C) 11.36 
D) 20.22

Question 20

Which of the following amino acids has a non-polar side chain?

Accepted Answer

A) histidine 
B) arginine 
C) glutamine 
D) valine 
A) histidine 
B) arginine 
C) glutamine 
D) valine

Exam 27: Amino Acids and Proteins

Which of the following tripeptides is not hydrolyzed by trypsin?

Structure _____ (shown below) will migrate toward the positive electrode in an electrophoresis experiment.

Which of the following amino acids is not chiral?

Which of the following is not a polypeptide?

What are the products of the reaction of alanine and ninhydrin (shown below)?

Consider the following form of phenylalanine. This form would exist at a pH _______than the pI.

Hydrogen bonds, α\alphaα -helices, and pleated sheets are properties of structure of proteins.

In Phe-Ile-Ser-Asp-Gly-His-Gly-Tyr, the three-letter abbreviation for the C-terminal amino acid is ________.

MATCH a structure from the list below to each of the following terms. Place the letter of the structure in the blank to the left of the term which it describes. -_____ is an octapeptide with a C-terminal valine.

What fragments are produced when porcine dynorphin, a peptide that contains 17 amino acid residues (shown below), is cleaved with trypsin?

Which of the following amino acids migrates to the positive electrode on paper electrophoresis at a pH of 7.0?

In the Edman degradation analysis of the N-terminus of a peptide the terminal residue reacts with phenyl isocyanate, an example is shown below. Provide the structure of both of the products of this reaction.

The Edman degradation is used to identify the ___-terminal amino acid of a peptide.

What is the major organic product of the following reaction?

Which of the following amino acids contains two stereocenters?

Which of the following reagents can be used to cleave a benzyloxycarbonyl protecting group from a peptide?

Which of the following amino acids is not an L-isomer?

The number of different combinations that are possible for a tripeptide containing one of each of the following amino acids: Phe, Val, Asp is ______.

What is the isoelectric point of serine (pKa of α\alphaα -CO2H, 2.21; pKa of α\alphaα -NH2, 9.15)?

Which of the following amino acids has a non-polar side chain?

Covalent Bonding and Shapes of Molecules

Alkanes and Cycloalkanes

Stereoisomerism and Chirality

Acids and Bases

Alkenes: Bonding, Nomenclature, and Properties

Reactions of Alkenes

Alkynes

Haloalkanes, Halogenation, and Radical Reactions

Nucleophilic Substitution and Beta-Elimination

Alcohols

Ethers, Epoxides, and Sulfides

Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Mass Spectrometry

An Introduction to Organometallic Compounds

Aldehydes and Ketones

Carboxylic Acids

Functional Derivatives of Carboxylic Acids

Enolate Anions and Enamines

Dienes, Conjugated Systems, and Pericyclic Reactions

Benzene and the Concept of Aromaticity

Reactions of Benzene and Its Derivatives

Amines

Catalytic Carbon-Carbon Bond Formation

Carbohydrates

Lipids

Nucleic Acids

Organic Polymer Chemistry

Filters

Hydrogen bonds, $\alpha$ -helices, and pleated sheets are properties of structure of proteins.

What is the isoelectric point of serine (pK_a of $\alpha$ -CO₂H, 2.21; pK_a of $\alpha$ -NH₂, 9.15)?