Exam 9: Nucleophilic Substitution and Beta-Elimination

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Consider the pair of reactions below to answer the following question(s). a. Consider the pair of reactions below to answer the following question(s). a.    or b.   -In the reactions a and b if concentration of OH<sup>-</sup> and SH<sup>-</sup>, respectively, were doubled, the rate of the reactions would ___________. or b. Consider the pair of reactions below to answer the following question(s). a.    or b.   -In the reactions a and b if concentration of OH<sup>-</sup> and SH<sup>-</sup>, respectively, were doubled, the rate of the reactions would ___________. -In the reactions a and b if concentration of OH- and SH-, respectively, were doubled, the rate of the reactions would ___________.

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The following reaction would be classified as an elimination. The following reaction would be classified as an elimination.

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What is(are) the major organic product(s) obtained from the following substitution reaction? What is(are) the major organic product(s) obtained from the following substitution reaction?

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Consider the reaction below to answer the following question(s). Consider the reaction below to answer the following question(s).   -Compound B by is formed by an _____ mechanism. -Compound B by is formed by an _____ mechanism.

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Which of the following most favors elimination rather substitution in a reaction with sodium methoxide?

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Which of the following is best set of conditions for the preparation of tert-butanol?

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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Which of the following anions is the best leaving group in an SN1 reaction?

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Which of the following most favors elimination rather substitution in a reaction with 2-bromopropane?

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What is(are) the major organic product(s) obtained from the following substitution reaction? What is(are) the major organic product(s) obtained from the following substitution reaction?

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Which of the following compounds undergoes the most rapid hydrolysis reaction? Which of the following compounds undergoes the most rapid hydrolysis reaction?

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What is the best choice of reagent to perform the following transformation? What is the best choice of reagent to perform the following transformation?

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Which of the following compounds is the most nucleophilic in polar protic solvents?

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What is the major organic product(s) obtained from the following reaction? What is the major organic product(s) obtained from the following reaction?

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Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene? Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene?

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Consider the pair of reactions below to answer the following question(s). a. Consider the pair of reactions below to answer the following question(s). a.    or b.   -These reactions are classified as ________________reactions. or b. Consider the pair of reactions below to answer the following question(s). a.    or b.   -These reactions are classified as ________________reactions. -These reactions are classified as ________________reactions.

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Which of the following represents the transition state of the rate-determining step in the reaction between tert-butyl iodide and water leading to elimination? Which of the following represents the transition state of the rate-determining step in the reaction between tert-butyl iodide and water leading to elimination?

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Which of the following alkyl halides undergoes the fastest solvolysis reaction with formic acid, HCOOH?

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Which of the following represents the transition state of the reaction between methyl iodide and ammonia? Which of the following represents the transition state of the reaction between methyl iodide and ammonia?

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