Question 1

Topical acyclovir will prevent transmission of herpes labialis.Topical acyclovir will prevent recurrence of herpes labialis.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement false,the second is true.

Question 2

Which type of herpes virus is transmitted to humans primarily by a monkey bite?

Accepted Answer

A) Herpes simplex type 1 
B) Herpes simplex type 2 
C) Herpes B virus 
D) Varicella-zoster 
A) Herpes simplex type 1 
B) Herpes simplex type 2 
C) Herpes B virus 
D) Varicella-zoster

Question 3

Ketoconazole should not be used with _____ because it could reduce the absorption of ketoconazole.

Accepted Answer

A) penicillin V 
B) metronidazole 
C) anticholinergic agents 
D) acyclovir 
A) penicillin V 
B) metronidazole 
C) anticholinergic agents 
D) acyclovir

Question 4

Which of the following is the usual adult dose of ketoconazole for the treatment of Candida species?

Accepted Answer

A) 5 ml of aqueous suspension (100,000 U/ml)four times daily 
B) 200 to 400 mg orally daily 
C) One pastille four to five times daily 
D) One troche one to five times daily 
A) 5 ml of aqueous suspension (100,000 U/ml)four times daily 
B) 200 to 400 mg orally daily 
C) One pastille four to five times daily 
D) One troche one to five times daily

Question 5

What is integrase in the context of infection with human immunodeficiency virus?

Accepted Answer

A) It measures the CD4 lymphocyte count to determine the health of the patient. 
B) It is a viral enzyme that inserts the viral genome into the DNA of the host cell. 
C) It prevents the cleavage of viral protein precursors needed to generate functional structural proteins in and modulation of reverse transcriptase activity. 
D) It terminates the synthesis of viral DNA. 
A) It measures the CD4 lymphocyte count to determine the health of the patient. 
B) It is a viral enzyme that inserts the viral genome into the DNA of the host cell. 
C) It prevents the cleavage of viral protein precursors needed to generate functional structural proteins in and modulation of reverse transcriptase activity. 
D) It terminates the synthesis of viral DNA.

Question 6

Which of the following antifungal agents is produced by Streptomyces noursei?

Accepted Answer

A) Fluconazole 
B) Clotrimazole 
C) Ketoconazole 
D) Nystatin 
A) Fluconazole 
B) Clotrimazole 
C) Ketoconazole 
D) Nystatin

Question 7

Oral candidal infections are often treatable with oral antifungal lozenges and rinses.

Accepted Answer

A) True 
 B)False

Question 8

Which dose form of acyclovir has been effective for the treatment of herpes labialis in an immunocompromised person?

Accepted Answer

A) Oral 
B) Topical 
C) Pastille 
D) Troche 
A) Oral 
B) Topical 
C) Pastille 
D) Troche

Question 9

Which of the following classes of drugs used to treat human immunodeficiency virus (HIV)block the progression from HIV infection to AIDS by preventing the passage of the virus across the human cell membrane?

Accepted Answer

A) Integrase inhibitor 
B) Nonnucleoside reverse transcriptase inhibitor 
C) Nucleoside/nucleotide reverse transcriptase inhibitor 
D) Entry inhibitor 
E) Protease inhibitor 
A) Integrase inhibitor 
B) Nonnucleoside reverse transcriptase inhibitor 
C) Nucleoside/nucleotide reverse transcriptase inhibitor 
D) Entry inhibitor 
E) Protease inhibitor

Question 10

Which of the following statements is true of zidovudine (AZT,Retrovir)?

Accepted Answer

A) It prevents cells containing human immunodeficiency virus (HIV)from replicating. 
B) The toxicity of zidovudine is related to bone marrow depression. 
C) It has no effect on the number and frequency of opportunistic infections. 
D) Both A and B are true. 
E) Both B and C are true. 
A) It prevents cells containing human immunodeficiency virus (HIV)from replicating. 
B) The toxicity of zidovudine is related to bone marrow depression. 
C) It has no effect on the number and frequency of opportunistic infections. 
D) Both A and B are true. 
E) Both B and C are true.

Question 11

Which of the following types of HIV drugs are also used to treat hepatitis B? (Select all that apply. )

Accepted Answer

A) Nucleoside analog or nucleoside/nucleotide reverse transcriptase inhibitors 
B) Nonnucleoside analogs or nonnucleoside reverse transcriptase inhibitor 
C) Protease inhibitor 
D) Fusion/entry inhibitor 
E) Integrase inhibitor 
A) Nucleoside analog or nucleoside/nucleotide reverse transcriptase inhibitors 
B) Nonnucleoside analogs or nonnucleoside reverse transcriptase inhibitor 
C) Protease inhibitor 
D) Fusion/entry inhibitor 
E) Integrase inhibitor

Question 12

Thrush is

Accepted Answer

A) an allergic reaction. 
B) an idiosyncrasy. 
C) oropharyngeal candidiasis. 
D) a serious systemic fungal infection. 
A) an allergic reaction. 
B) an idiosyncrasy. 
C) oropharyngeal candidiasis. 
D) a serious systemic fungal infection.

Question 13

Viruses are difficult to treat because they cooperate with the host's cells.

Accepted Answer

A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true. 
A) Both statements are true. 
B) Both statements are false. 
C) The first statement is true,the second is false. 
D) The first statement is false,the second is true.

Question 14

The mechanism of action of nystatin involves binding to the

Accepted Answer

A) 30S ribosomal subunit of bacterial rRNA. 
B) 50S ribosomal subunit of bacterial rRNA. 
C) sterols in the fungal cell membrane. 
D) enzymes in the nucleus of molds. 
A) 30S ribosomal subunit of bacterial rRNA. 
B) 50S ribosomal subunit of bacterial rRNA. 
C) sterols in the fungal cell membrane. 
D) enzymes in the nucleus of molds.

Question 15

Which of the following two types of hepatitis account for almost two-thirds of all cases of hepatitis?

Accepted Answer

A) A and B 
B) A and C 
C) B and C 
D) C and D 
A) A and B 
B) A and C 
C) B and C 
D) C and D

Question 16

Topical acyclovir can prevent the recurrence of herpes labialis.

Accepted Answer

A) True 
 B)False

Question 17

The most serious adverse reaction associated with ketoconazole is

Accepted Answer

A) tachycardia. 
B) hepatotoxicity. 
C) hypotension. 
D) achlorhydria. 
A) tachycardia. 
B) hepatotoxicity. 
C) hypotension. 
D) achlorhydria.

Question 18

No acyclovir products are approved for the treatment of recurrent herpes labialis in the immunocompetent patient.

Accepted Answer

A) True 
 B)False

Question 19

All currently available interferons are parenteral.

Accepted Answer

A) True 
 B)False

Question 20

Which of the following is true of acyclovir?

Accepted Answer

A) It works by inhibiting replication of deoxyribonucleic acid (DN
A) . 
B) It should be taken on an empty stomach because food affects the drug's absorption. 
C) The antiviral action of acyclovir includes herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2),but it is not effective against varicella-zoster virus or Epstein-Barr virus. 
D) The most common adverse effects associated with oral acyclovir are anorexia and a funny taste in the mouth. 
A) It works by inhibiting replication of deoxyribonucleic acid (DN
A) . 
B) It should be taken on an empty stomach because food affects the drug's absorption. 
C) The antiviral action of acyclovir includes herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2),but it is not effective against varicella-zoster virus or Epstein-Barr virus. 
D) The most common adverse effects associated with oral acyclovir are anorexia and a funny taste in the mouth.

Exam 8: Antifungal and Antiviral Agents

Topical acyclovir will prevent transmission of herpes labialis.Topical acyclovir will prevent recurrence of herpes labialis.

Which type of herpes virus is transmitted to humans primarily by a monkey bite?

Ketoconazole should not be used with _____ because it could reduce the absorption of ketoconazole.

Which of the following is the usual adult dose of ketoconazole for the treatment of Candida species?

What is integrase in the context of infection with human immunodeficiency virus?

Which of the following antifungal agents is produced by Streptomyces noursei?

Oral candidal infections are often treatable with oral antifungal lozenges and rinses.

Which dose form of acyclovir has been effective for the treatment of herpes labialis in an immunocompromised person?

Which of the following classes of drugs used to treat human immunodeficiency virus (HIV)block the progression from HIV infection to AIDS by preventing the passage of the virus across the human cell membrane?

Which of the following statements is true of zidovudine (AZT,Retrovir)?

Which of the following types of HIV drugs are also used to treat hepatitis B? (Select all that apply. )

Thrush is

Viruses are difficult to treat because they cooperate with the host's cells.

The mechanism of action of nystatin involves binding to the

Which of the following two types of hepatitis account for almost two-thirds of all cases of hepatitis?

Topical acyclovir can prevent the recurrence of herpes labialis.

The most serious adverse reaction associated with ketoconazole is

No acyclovir products are approved for the treatment of recurrent herpes labialis in the immunocompetent patient.

All currently available interferons are parenteral.

Which of the following is true of acyclovir?

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