Question 1

In the autonomic nervous system (ANS),the target organ is innervated by the _____ neuron.

Accepted Answer

A) preganglionic afferent 
B) preganglionic efferent 
C) postganglionic afferent 
D) postganglionic efferent 
A) preganglionic afferent 
B) preganglionic efferent 
C) postganglionic afferent 
D) postganglionic efferent

Question 2

Tertiary anticholinergic agents are _____ soluble and _____ penetrate the brain.

Accepted Answer

A) lipid soluble;easily 
B) lipid soluble;do not 
C) not lipid soluble;easily 
D) not lipid soluble;do not 
A) lipid soluble;easily 
B) lipid soluble;do not 
C) not lipid soluble;easily 
D) not lipid soluble;do not

Question 3

Which type of agent such as donepezil (Aricept)has been FDA approved for the treatment of dementia?

Accepted Answer

A) Cholinergic agents 
B) Anticholinergic agents 
C) Adrenergic agents 
D) Adrenergic blocking agents 
A) Cholinergic agents 
B) Anticholinergic agents 
C) Adrenergic agents 
D) Adrenergic blocking agents

Question 4

The fight-or-flight response refers to activation of the parasympathetic nervous system in response to stress.

Accepted Answer

A) True 
 B)False

Question 5

Patients pretreated with _____ agents are prone to epinephrine reversal.

Accepted Answer

A) cholinergic 
B) anticholinergic 
C) a-adrenergic 
D) a-adrenergic blocking 
A) cholinergic 
B) anticholinergic 
C) a-adrenergic 
D) a-adrenergic blocking

Question 6

Sarin was used on a subway in Japan to poison riders.Sarin is a(n)

Accepted Answer

A) sympathomimetic. 
B) anticholinergic. 
C) anticholinesterase. 
D) sympatholytic. 
A) sympathomimetic. 
B) anticholinergic. 
C) anticholinesterase. 
D) sympatholytic.

Question 7

Sympathomimetic agents should be used with caution in patients with (1)angina, (2)hypertension, (3)hypothyroidism.

Accepted Answer

A) 1,2,3 
B) 1,2 
C) 1,3 
D) 2,3 
A) 1,2,3 
B) 1,2 
C) 1,3 
D) 2,3

Question 8

a-Adrenergic agonists cause

Accepted Answer

A) vasoconstriction. 
B) vasodilation. 
C) tachycardia. 
D) miosis. 
A) vasoconstriction. 
B) vasodilation. 
C) tachycardia. 
D) miosis.

Question 9

Norepinephrine is the neurotransmitter of the

Accepted Answer

A) pre-ganglionic nerve of the sympathetic division of the autonomic nervous system. 
B) post-ganglionic nerve of the sympathetic division of the autonomic nervous system. 
C) pre-ganglionic nerve of the parasympathetic division of the autonomic nervous system. 
D) post-ganglionic nerve of the parasympathetic division of the autonomic nervous system. 
A) pre-ganglionic nerve of the sympathetic division of the autonomic nervous system. 
B) post-ganglionic nerve of the sympathetic division of the autonomic nervous system. 
C) pre-ganglionic nerve of the parasympathetic division of the autonomic nervous system. 
D) post-ganglionic nerve of the parasympathetic division of the autonomic nervous system.

Question 10

Which of the following choices would occur during a generalized discharge of the sympathetic nervous system?

Accepted Answer

A) Diarrhea 
B) Urination 
C) Glycogen breakdown 
D) Miosis 
E) None of the above 
A) Diarrhea 
B) Urination 
C) Glycogen breakdown 
D) Miosis 
E) None of the above

Question 11

The following statements are true of d-tubocurarine except which one?

Accepted Answer

A) It is a competitive nondepolarizing blocker. 
B) It binds to nicotinic receptors. 
C) It precipitates malignant hyperthermia in susceptible patients when combined with halothane. 
D) It has been used in the Amazon for hunting animals. 
E) Its action can be overcome by administering neostigmine. 
A) It is a competitive nondepolarizing blocker. 
B) It binds to nicotinic receptors. 
C) It precipitates malignant hyperthermia in susceptible patients when combined with halothane. 
D) It has been used in the Amazon for hunting animals. 
E) Its action can be overcome by administering neostigmine.

Question 12

The parasympathetic fibers originate in the nuclei of the _____ segments of the spinal cord.

Accepted Answer

A) sacral and lumbar 
B) cranial nerves and sacral 
C) cranial nerves and lumbar 
D) thoracic and lumbar 
E) None of the above are correct. 
A) sacral and lumbar 
B) cranial nerves and sacral 
C) cranial nerves and lumbar 
D) thoracic and lumbar 
E) None of the above are correct.

Question 13

Indications for the use of anticholinergic agents include

Accepted Answer

A) stimulation of salivary secretion for xerostomic patients. 
B) treatment of gastrointestinal disorders associated with decreased motility. 
C) treatment in combination with levodopa for patients with Parkinson disease. 
D) use as an antipsychotic. 
A) stimulation of salivary secretion for xerostomic patients. 
B) treatment of gastrointestinal disorders associated with decreased motility. 
C) treatment in combination with levodopa for patients with Parkinson disease. 
D) use as an antipsychotic.

Question 14

The action of norepinephrine is terminated by which of the following choices?

Accepted Answer

A) Uptake into the presynaptic nerve terminal by an amine-specific pump 
B) Action of catechol-O-methyltransferase (COMT) 
C) Action of monoamine oxidase (MAO) 
D) All of the above 
E) None of the above 
A) Uptake into the presynaptic nerve terminal by an amine-specific pump 
B) Action of catechol-O-methyltransferase (COMT) 
C) Action of monoamine oxidase (MAO) 
D) All of the above 
E) None of the above

Question 15

Which of the following agents is known to deplete endogenous norepinephrine?

Accepted Answer

A) Propranolol 
B) Reserpine 
C) Phentolamine 
D) Yohimbine 
E) None of the above 
A) Propranolol 
B) Reserpine 
C) Phentolamine 
D) Yohimbine 
E) None of the above

Question 16

Glycopyrrolate is an a-adrenergic agonist used to produce a dry field before some dental procedures.

Accepted Answer

A) True 
 B)False

Question 17

Which of the following conditions is not a relative contraindication or caution with the use of cholinergic agents?

Accepted Answer

A) Bronchial asthma 
B) Hypothyroidism 
C) Myasthenia gravis treated with neostigmine 
D) Peptic ulcer 
A) Bronchial asthma 
B) Hypothyroidism 
C) Myasthenia gravis treated with neostigmine 
D) Peptic ulcer

Question 18

Muscarinic receptors are found in which of the following? (Select all that apply. )

Accepted Answer

A) Central nervous system 
B) Sympathetic nervous system 
C) Parasympathetic nervous system 
D) Neuromuscular junction 
E) Adrenal medulla 
A) Central nervous system 
B) Sympathetic nervous system 
C) Parasympathetic nervous system 
D) Neuromuscular junction 
E) Adrenal medulla

Question 19

Which is true of glycopyrrolate (Robinul)?

Accepted Answer

A) It is a tertiary anticholinergic agent. 
B) It is a quaternary anticholinergic agent. 
C) It is lipid soluble and easily penetrates the brain. 
D) It is a cholinergic agent. 
A) It is a tertiary anticholinergic agent. 
B) It is a quaternary anticholinergic agent. 
C) It is lipid soluble and easily penetrates the brain. 
D) It is a cholinergic agent.

Question 20

Which of the following substances will block the action of acetylcholine at the postganglionic endings in the parasympathetic autonomic nervous system (PANS)?

Accepted Answer

A) Atropine 
B) Curare 
C) Hexamethonium 
D) Acetic acid 
A) Atropine 
B) Curare 
C) Hexamethonium 
D) Acetic acid

Exam 4: Autonomic Drugs

In the autonomic nervous system (ANS),the target organ is innervated by the _____ neuron.

Tertiary anticholinergic agents are _____ soluble and _____ penetrate the brain.

Which type of agent such as donepezil (Aricept)has been FDA approved for the treatment of dementia?

The fight-or-flight response refers to activation of the parasympathetic nervous system in response to stress.

Patients pretreated with _____ agents are prone to epinephrine reversal.

Sarin was used on a subway in Japan to poison riders.Sarin is a(n)

Sympathomimetic agents should be used with caution in patients with (1)angina, (2)hypertension, (3)hypothyroidism.

a-Adrenergic agonists cause

Norepinephrine is the neurotransmitter of the

Which of the following choices would occur during a generalized discharge of the sympathetic nervous system?

The following statements are true of d-tubocurarine except which one?

The parasympathetic fibers originate in the nuclei of the _____ segments of the spinal cord.

Indications for the use of anticholinergic agents include

The action of norepinephrine is terminated by which of the following choices?

Which of the following agents is known to deplete endogenous norepinephrine?

Glycopyrrolate is an a-adrenergic agonist used to produce a dry field before some dental procedures.

Which of the following conditions is not a relative contraindication or caution with the use of cholinergic agents?

Muscarinic receptors are found in which of the following? (Select all that apply. )

Which is true of glycopyrrolate (Robinul)?

Which of the following substances will block the action of acetylcholine at the postganglionic endings in the parasympathetic autonomic nervous system (PANS)?

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