Question 1

The length of time it takes for the cells labeled during DNA synthesis to begin to enter mitosis is a good estimate of the length of the _______ phase(s).

Accepted Answer

A)  G1 
B)  S 
C)  G2 
D)  M 
A)  G1 
B)  S 
C)  G2 
D)  M

Question 2

Damaged DNA is sensed by a complex of proteins that activate the protein kinase

Accepted Answer

A)  ATM or ATR. 
B)  ABS. 
C)  Akt. 
D)  MCM. 
A)  ATM or ATR. 
B)  ABS. 
C)  Akt. 
D)  MCM.

Question 3

The spindle assembly checkpoint monitors the alignment of chromosomes in the mitotic spindle during mitosis to insure an even distribution of chromosomes to each of the daughter cells. If the chromosomes do not align properly, the spindle assembly checkpoint will arrest cells in what phase of mitosis?

Accepted Answer

A)  Prophase 
B)  Metaphase 
C)  Anaphase 
D)  Telophase 
A)  Prophase 
B)  Metaphase 
C)  Anaphase 
D)  Telophase

Question 4

The sequence of DNA on each chromosome where the sister chromatids are held together is called the

Accepted Answer

A)  centrosome. 
B)  kinetochore. 
C)  centromere. 
D)  centriole. 
A)  centrosome. 
B)  kinetochore. 
C)  centromere. 
D)  centriole.

Question 5

During prophase, Cdk1/Cyclin B (MPF) directly phosphorylates all of the following except

Accepted Answer

A)  condensins. 
B)  lamins. 
C)  APC/C. 
D)  microtubule-associated proteins. 
A)  condensins. 
B)  lamins. 
C)  APC/C. 
D)  microtubule-associated proteins.

Question 6

Cdks bind to cyclin and are activated by

Accepted Answer

A)  phosphorylation by Wee1. 
B)  dephosphorylation by Cdc25 protein phosphatase. 
C)  the binding of Ink4. 
D)  the binding of Cip. 
A)  phosphorylation by Wee1. 
B)  dephosphorylation by Cdc25 protein phosphatase. 
C)  the binding of Ink4. 
D)  the binding of Cip.

Question 7

Describe the pathway by which growth factors signal passage through the restriction point in late G1.

Accepted Answer

Extracellular growth factors stimulate t

Question 8

Using the CRISPR/Cas system in a cell culture model, you mutate the gene encoding condensin so that it now encodes a nonfunctional product. What would be the predicted phenotype for these cells?

Accepted Answer

The role of condensins is to direct the

Question 9

Re-formation of the nuclear envelope occurs as the result of cyclin B destruction, which allows phosphatases to dephosphorylate nuclear envelope lamins.

Accepted Answer

A) True 
 B)False

Question 10

ATM recognizes single-stranded DNA breaks and ATR recognizes double-stranded DNA breaks.

Accepted Answer

A) True 
 B)False

Question 11

Which statement regarding cyclin D is false?

Accepted Answer

A)  It is required for cell cycle progression. 
B)  It is activated by growth factors. 
C)  It is always present and its activity is regulated by fluctuating levels of Cdk4 and Cdk6. 
D)  It is rapidly degraded following removal of appropriate growth factors. 
A)  It is required for cell cycle progression. 
B)  It is activated by growth factors. 
C)  It is always present and its activity is regulated by fluctuating levels of Cdk4 and Cdk6. 
D)  It is rapidly degraded following removal of appropriate growth factors.

Question 12

The mechanism of cytokinesis in plants involves the formation of the

Accepted Answer

A)  contractile ring. 
B)  Aurora belt. 
C)  cell plate. 
D)  plasma membrane bridge. 
A)  contractile ring. 
B)  Aurora belt. 
C)  cell plate. 
D)  plasma membrane bridge.

Question 13

Which statement about cyclin B is false?

Accepted Answer

A)  It is a component of MPF. 
B)  It accumulates throughout S and G2. 
C)  It activates Cdc2 protein kinase. 
D)  It cycles between active and inactive states in the cell cycle. 
A)  It is a component of MPF. 
B)  It accumulates throughout S and G2. 
C)  It activates Cdc2 protein kinase. 
D)  It cycles between active and inactive states in the cell cycle.

Question 14

Dephosphorylation of proteins that were phosphorylated during prophase leads to what three telophase events?

Accepted Answer

(1) Chromosome decondensation;

Question 15

Cytokinesis occurs in a plane that passes through which area of a cell?

Accepted Answer

The answer of Cytokinesis occurs in a plane that passes...

Question 16

What does the spindle assembly checkpoint prevent?

Accepted Answer

It prevents chromosomes from s

Question 17

Passage of animal cells through the cell cycle is regulated primarily by

Accepted Answer

A)  the availability of nutrients. 
B)  intracellular second messengers. 
C)  extracellular growth factors. 
D)  direct cell surface interactions. 
A)  the availability of nutrients. 
B)  intracellular second messengers. 
C)  extracellular growth factors. 
D)  direct cell surface interactions.

Question 18

Which of the following are not phosphorylated by the Cdk1/cyclin B complex during mitosis?

Accepted Answer

A)  H3 histones 
B)  Golgi matrix proteins 
C)  Nuclear lamins 
D)  Condensins 
A)  H3 histones 
B)  Golgi matrix proteins 
C)  Nuclear lamins 
D)  Condensins

Question 19

p21 inhibits cell cycle progression by binding to and inhibiting

Accepted Answer

A)  cyclin-dependent kinases. 
B)  p53. 
C)  ATM. 
D)  Rb protein. 
A)  cyclin-dependent kinases. 
B)  p53. 
C)  ATM. 
D)  Rb protein.

Question 20

Nuclear envelope breakdown occurs at the

Accepted Answer

A)  beginning of prophase. 
B)  end of prophase. 
C)  end of prometaphase. 
D)  beginning of anaphase. 
A)  beginning of prophase. 
B)  end of prophase. 
C)  end of prometaphase. 
D)  beginning of anaphase.

The length of time it takes for the cells labeled during DNA synthesis to begin to enter mitosis is a good estimate of the length of the _______ phase(s).

Damaged DNA is sensed by a complex of proteins that activate the protein kinase

The sequence of DNA on each chromosome where the sister chromatids are held together is called the

During prophase, Cdk1/Cyclin B (MPF) directly phosphorylates all of the following except

Cdks bind to cyclin and are activated by

Describe the pathway by which growth factors signal passage through the restriction point in late G₁.

Using the CRISPR/Cas system in a cell culture model, you mutate the gene encoding condensin so that it now encodes a nonfunctional product. What would be the predicted phenotype for these cells?

Re-formation of the nuclear envelope occurs as the result of cyclin B destruction, which allows phosphatases to dephosphorylate nuclear envelope lamins.

ATM recognizes single-stranded DNA breaks and ATR recognizes double-stranded DNA breaks.

Which statement regarding cyclin D is false?

The mechanism of cytokinesis in plants involves the formation of the

Which statement about cyclin B is false?

Dephosphorylation of proteins that were phosphorylated during prophase leads to what three telophase events?

Cytokinesis occurs in a plane that passes through which area of a cell?

What does the spindle assembly checkpoint prevent?

Passage of animal cells through the cell cycle is regulated primarily by

Which of the following are not phosphorylated by the Cdk1/cyclin B complex during mitosis?

p21 inhibits cell cycle progression by binding to and inhibiting

Nuclear envelope breakdown occurs at the

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

Cell Death and Cell Renewal

Cancer

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Exam 18: The Cell Cycle

The length of time it takes for the cells labeled during DNA synthesis to begin to enter mitosis is a good estimate of the length of the _______ phase(s).

Damaged DNA is sensed by a complex of proteins that activate the protein kinase

The sequence of DNA on each chromosome where the sister chromatids are held together is called the

During prophase, Cdk1/Cyclin B (MPF) directly phosphorylates all of the following except

Cdks bind to cyclin and are activated by

Describe the pathway by which growth factors signal passage through the restriction point in late G1.

Using the CRISPR/Cas system in a cell culture model, you mutate the gene encoding condensin so that it now encodes a nonfunctional product. What would be the predicted phenotype for these cells?

Re-formation of the nuclear envelope occurs as the result of cyclin B destruction, which allows phosphatases to dephosphorylate nuclear envelope lamins.

ATM recognizes single-stranded DNA breaks and ATR recognizes double-stranded DNA breaks.

Which statement regarding cyclin D is false?

The mechanism of cytokinesis in plants involves the formation of the

Which statement about cyclin B is false?

Dephosphorylation of proteins that were phosphorylated during prophase leads to what three telophase events?

Cytokinesis occurs in a plane that passes through which area of a cell?

What does the spindle assembly checkpoint prevent?

Passage of animal cells through the cell cycle is regulated primarily by

Which of the following are not phosphorylated by the Cdk1/cyclin B complex during mitosis?

p21 inhibits cell cycle progression by binding to and inhibiting

Nuclear envelope breakdown occurs at the

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

Cell Death and Cell Renewal

Cancer

Filters

Describe the pathway by which growth factors signal passage through the restriction point in late G₁.