Question 1

Which of the following does NOT influence immunogenicity?

Accepted Answer

A)  the routes of administration 
B)  foreign nature of the immunogen to the host 
C)  solubility 
D)  All of these influence immunogenicity. 
A)  the routes of administration 
B)  foreign nature of the immunogen to the host 
C)  solubility 
D)  All of these influence immunogenicity.

Question 2

A diagnostic test for M. tuberculosis exposure

Accepted Answer

A)  utilizes an inflammatory reaction that occurs if there has been previous exposure to M. tuberculosis antigens. 
B)  relies on previous tuberculin vaccination. 
C)  uses an antiserum to detect antibodies in the blood that are only formed if there has been previous exposure to M. tuberculosis antigens. 
D)  relies on an innate immune response that occurs only if there has been previous exposure to M. tuberculosis antigens. 
A)  utilizes an inflammatory reaction that occurs if there has been previous exposure to M. tuberculosis antigens. 
B)  relies on previous tuberculin vaccination. 
C)  uses an antiserum to detect antibodies in the blood that are only formed if there has been previous exposure to M. tuberculosis antigens. 
D)  relies on an innate immune response that occurs only if there has been previous exposure to M. tuberculosis antigens.

Question 3

Superantigens produce a harmful immune response because

Accepted Answer

A)  they activate too many T cells, causing excessive inflammation and cell damage. 
B)  they initiate a type I allergic response resulting in excessive inflammation. 
C)  too many phagocytes are activated and destroy host tissue. 
D)  a strong immune response is necessary to protect the host from the pathogen. 
A)  they activate too many T cells, causing excessive inflammation and cell damage. 
B)  they initiate a type I allergic response resulting in excessive inflammation. 
C)  too many phagocytes are activated and destroy host tissue. 
D)  a strong immune response is necessary to protect the host from the pathogen.

Question 4

TC cells express a(n) ________ protein co-receptor.

Accepted Answer

A)  CD4 
B)  CD8 
C)  IgM 
D)  IgG 
A)  CD4 
B)  CD8 
C)  IgM 
D)  IgG

Question 5

The invariant amino acids in each peptide motif bound by MHC proteins are called

Accepted Answer

A)  anchor residues. 
B)  MHC peptides. 
C)  antigen-binding immunoglobulins. 
D)  TCR peptides. 
A)  anchor residues. 
B)  MHC peptides. 
C)  antigen-binding immunoglobulins. 
D)  TCR peptides.

Question 6

TH cells express a ________ protein coreceptor.

Accepted Answer

A)  CD4 
B)  CD8 
C)  CD12 
D)  T cell receptin 
A)  CD4 
B)  CD8 
C)  CD12 
D)  T cell receptin

Question 7

The ________ and ________ domains of the class II MHC protein interact to form a peptide-binding site.

Accepted Answer

A)  B / T 
B)  light / heavy 
C)  C / V 
D)  α1 / β1 
A)  B / T 
B)  light / heavy 
C)  C / V 
D)  α1 / β1

Question 8

All the following can cause contact dermatitis EXCEPT

Accepted Answer

A)  jewelry. 
B)  latex gloves. 
C)  poison ivy. 
D)  superantigens. 
A)  jewelry. 
B)  latex gloves. 
C)  poison ivy. 
D)  superantigens.

Question 9

________ is the acquired inability to mount an adaptive immune response against self.

Accepted Answer

A)  Memory 
B)  Specificity 
C)  Tolerance 
D)  Immunogenicity 
A)  Memory 
B)  Specificity 
C)  Tolerance 
D)  Immunogenicity

Question 10

Why is the secondary immune response stronger in regard to antibodies?

Accepted Answer

Somatic hypermutation creates B cells be

Question 11

Why must the adaptive immune system develop a capacity to discriminate between foreign antigens and host antigens?

Accepted Answer

Because all macromolecules in the host a

Question 12

Self-reactive T cells are eliminated during the development of tolerance in the immune system.

Accepted Answer

A) True 
 B)False

Exam 27: Adaptive Immunity: Highly Specific Host Defenses

Which of the following does NOT influence immunogenicity?

A diagnostic test for M. tuberculosis exposure

Superantigens produce a harmful immune response because

TC cells express a(n) ________ protein co-receptor.

The invariant amino acids in each peptide motif bound by MHC proteins are called

TH cells express a ________ protein coreceptor.

The ________ and ________ domains of the class II MHC protein interact to form a peptide-binding site.

All the following can cause contact dermatitis EXCEPT

________ is the acquired inability to mount an adaptive immune response against self.

Why is the secondary immune response stronger in regard to antibodies?

Why must the adaptive immune system develop a capacity to discriminate between foreign antigens and host antigens?

Self-reactive T cells are eliminated during the development of tolerance in the immune system.

The Microbial World

Microbial Cell Structure and Function

Microbial Metabolism

Molecular Information Flow and Protein Processing

Microbial Growth and Its Control

Microbial Regulatory Systems

Molecular Biology of Microbial Growth

Viruses and Their Replication

Microbial Systems Biology

Viral Genomics, Diversity, and Ecology

Genetics of Bacteria and Archaea

Biotechnology and Synthetic Biology

Microbial Evolution and Systematics

Metabolic Diversity of Microorganisms

Functional Diversity of Microorganisms

Diversity of Bacteria

Diversity of Archaea

Diversity of Microbial Eukarya

Taking the Measure of Microbial Systems

Microbial Ecosystems

Nutrient Cycles

Microbiology of the Built Environment

Microbial Symbioses

Microbial Symbioses with Humans

Microbial Infection and Pathogenesis

Innate Immunity: Broadly Specific Host Defenses

Clinical Microbiology and Immunology

Epidemiology

Person-to-Person Bacterial and Viral Diseases

Vectorborne and Soilborne Bacterial and Viral Diseases

Waterborne and Foodborne Bacterial and Viral Diseases

Eukaryotic Pathogens: Fungi, Protozoans, and Helminths

Filters

The and domains of the class II MHC protein interact to form a peptide-binding site.