Exam 27: Adaptive Immunity: Highly Specific Host Defenses

The occurrence of multiple alleles at a specific locus is called

Which antibodies bind complement?

Class I MHC proteins are found ONLY on the surface of B lymphocytes, macrophages, and dendritic cells.

The transfer of antibodies through the placenta from mother to fetus is an example of

In somatic hypermutation, the mutation of immunoglobulin genes occurs at much higher rates than the mutation rates observed in other genes.

Th17 cells are important in the first stages of the adaptive immune response.

T cell receptors on a particular T cell can recognize more than two antigens.

The antigen-binding site of an antibody accommodates a small portion of the antigen called a(n)

After a B cell is activated, it no longer needs T cell interactions or cytokines to make antibody.

The ________ is a highly conserved amino acid sequence found in immunoglobulin, TCR, and MHC proteins.

What are the major antigenic barriers for tissue transplantation from one individual to another?

Which of the following is the name of the heavy chain constant domain of an IgD antibody?

Individuals with severe combined immunodeficiency syndrome (SCID) have a genetic defect that prevents proper formation and expression of immunoglobins and T cells and therefore do not have adaptive immunity.

Systemic lupus erythematosus (SLE) is an example of a disease caused by type ________ hypersensitivity.

The part of the antigen recognized by the antibody or TCR is called the

Affinity maturation is one of the factors responsible for a stronger secondary immune response.

Antibody-mediated immunity is particularly effective against

The peptides bound by a single MHC protein share a common

Assuming that each heavy and light chain has an equal chance to be expressed in each cell, approximately how many possible antibodies can be expressed?

Differentiate between T-cytotoxic (TC) cells and T-helper (TH) cells.