Question 1

Which of the following statements about type I reactions is FALSE?

Accepted Answer

A)  The symptoms are due to histamine. 
B)  They involve helper T cells. 
C)  Antibodies bind to mast cells and basophils. 
D)  The symptoms occur soon after exposure to an antigen. 
E)  They involve IgE antibodies. 
A)  The symptoms are due to histamine. 
B)  They involve helper T cells. 
C)  Antibodies bind to mast cells and basophils. 
D)  The symptoms occur soon after exposure to an antigen. 
E)  They involve IgE antibodies.

Question 2

Treatment with certain drugs to reduce transplant rejection can cause

Accepted Answer

A)  immunologic surveillance. 
B)  immunotherapy. 
C)  immunologic enhancement. 
D)  immunosuppression. 
E)  autoimmunity. 
A)  immunologic surveillance. 
B)  immunotherapy. 
C)  immunologic enhancement. 
D)  immunosuppression. 
E)  autoimmunity.

Question 3

All hypersensitivities involve antibody- antigen reactions.

Accepted Answer

A) True 
 B)False

Question 4

Which of the following describes a cytotoxic autoimmune reaction?

Accepted Answer

A)  Antibodies are not made. 
B)  Antibodies react to cell- surface antigens. 
C)  Mediate by T cells. 
D)  Cells are killed. 
E)  Immune complexes form. 
A)  Antibodies are not made. 
B)  Antibodies react to cell- surface antigens. 
C)  Mediate by T cells. 
D)  Cells are killed. 
E)  Immune complexes form.

Question 5

The process of desensitization to prevent allergies involves the injection of increasing amounts of

Accepted Answer

A)  RhoGAM. 
B)  antihistamine. 
C)  IgE. 
D)  antigen. 
E)  IgG. 
A)  RhoGAM. 
B)  antihistamine. 
C)  IgE. 
D)  antigen. 
E)  IgG.

Question 6

Which antibodies will be in the serum of a person with blood type B, Rh+?

Accepted Answer

A)  anti- B 
B)  anti- B, anti- Rh 
C)  anti- A, anti- Rh 
D)  anti- A, anti- B, anti- Rh 
E)  anti- A 
A)  anti- B 
B)  anti- B, anti- Rh 
C)  anti- A, anti- Rh 
D)  anti- A, anti- B, anti- Rh 
E)  anti- A

Question 7

Figure 19.1
  
-In immune complex reaction shown in Figure 19.1, what is the structure labeled "a"?

Accepted Answer

A)  complement 
B)  antigen 
C)  mast cell 
D)  antibody 
E)  neutrophil 
A)  complement 
B)  antigen 
C)  mast cell 
D)  antibody 
E)  neutrophil

Question 8

Explain why a transplant tissue would be rejected if that tissue had different HLAs compared to the HLAs of the recipient. How can this rejection be decreased?

Accepted Answer

When a transplant tissue has different h

Question 9

All stem cells are derived from embryonic stem cells.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following statements about type IV reactions is FALSE?

Accepted Answer

A)  Reactions are not apparent for a day or more. 
B)  Reactions are primarily due to T cell proliferation. 
C)  Cytokines initiate tissue damage. 
D)  Allergic contact dermatitis is an example. 
E)  Hemolytic disease of the newborn is an example. 
A)  Reactions are not apparent for a day or more. 
B)  Reactions are primarily due to T cell proliferation. 
C)  Cytokines initiate tissue damage. 
D)  Allergic contact dermatitis is an example. 
E)  Hemolytic disease of the newborn is an example.

Question 11

Attachment of HIV to the target cell depends on

Accepted Answer

A)  gp120 combining with the chemokine receptor CCR5. 
B)  gp120 combining with the CD4+ receptor. 
C)  CXCR4 binding to the CD4+ receptor. 
D)  gp120 binding to the CD4+ plasma membrane. 
E)  gp41 binding to the CD4+ receptor. 
A)  gp120 combining with the chemokine receptor CCR5. 
B)  gp120 combining with the CD4+ receptor. 
C)  CXCR4 binding to the CD4+ receptor. 
D)  gp120 binding to the CD4+ plasma membrane. 
E)  gp41 binding to the CD4+ receptor.

Question 12

Allergic contact dermatitis is due to

Accepted Answer

A)  activated macrophages. 
B)  sensitized T cells. 
C)  IgM antibodies. 
D)  IgG antibodies. 
E)  IgE antibodies. 
A)  activated macrophages. 
B)  sensitized T cells. 
C)  IgM antibodies. 
D)  IgG antibodies. 
E)  IgE antibodies.

Question 13

Hemolytic disease of the newborn can result from an

Accepted Answer

A)  Rh- mother with an Rh+ fetus. 
B)  AB mother with an O fetus. 
C)  Rh+ mother with an Rh- fetus. 
D)  Rh- mother and an A fetus. 
E)  AB mother with a B fetus. 
A)  Rh- mother with an Rh+ fetus. 
B)  AB mother with an O fetus. 
C)  Rh+ mother with an Rh- fetus. 
D)  Rh- mother and an A fetus. 
E)  AB mother with a B fetus.

Question 14

All of the following are false regarding Herceptin EXCEPT

Accepted Answer

A)  it neutralizes the growth factor EGF. 
B)  it is a vaccine to prevent the development of cancer. 
C)  it acts as an immunotoxin to target and kill cancer cells. 
D)  it is an endotoxin that stimulates TNF by macrophages. 
E)  it is used to treat some breast cancer patients. 
A)  it neutralizes the growth factor EGF. 
B)  it is a vaccine to prevent the development of cancer. 
C)  it acts as an immunotoxin to target and kill cancer cells. 
D)  it is an endotoxin that stimulates TNF by macrophages. 
E)  it is used to treat some breast cancer patients.

Question 15

HIV attack of CD4+ T cells causes suppression of both cell- mediated and humoral immune responses.

Accepted Answer

A) True 
 B)False

Question 16

Which of the following is the least likely vaccine against HIV?

Accepted Answer

A)  subunit 
B)  glycoprotein 
C)  protein core 
D)  attenuated virus 
E)  All of these vaccines are equally likely. 
A)  subunit 
B)  glycoprotein 
C)  protein core 
D)  attenuated virus 
E)  All of these vaccines are equally likely.

Question 17

A healthy immune system destroys cancer cells with

Accepted Answer

A)  CTLs. 
B)  activated macrophages. 
C)  CD+ T cells. 
D)  CTLs and activated macrophages. 
E)  tumor- specific antigens. 
A)  CTLs. 
B)  activated macrophages. 
C)  CD+ T cells. 
D)  CTLs and activated macrophages. 
E)  tumor- specific antigens.

Question 18

Immunodeficiencies are a result of all of the following EXCEPT

Accepted Answer

A)  DiGeorge syndrome. 
B)  autoimmune diseases. 
C)  cyclosporine. 
D)  Hodgkin's disease. 
E)  HIV infection. 
A)  DiGeorge syndrome. 
B)  autoimmune diseases. 
C)  cyclosporine. 
D)  Hodgkin's disease. 
E)  HIV infection.

Question 19

Figure 19.1
  
-In immune complex reaction shown in Figure 19.1, what is the end result of the reaction?

Accepted Answer

A)  IgG is directed against cell membrane antigens. 
B)  Endothelial cells are damaged. 
C)  Antibodies destroy neutrophils. 
D)  Complement is activated. 
E)  Neutrophils are attracted and release enzymes. 
A)  IgG is directed against cell membrane antigens. 
B)  Endothelial cells are damaged. 
C)  Antibodies destroy neutrophils. 
D)  Complement is activated. 
E)  Neutrophils are attracted and release enzymes.

Question 20

Individuals who do not express CCR5 are highly resistant to infection by HIV.

Accepted Answer

A) True 
 B)False

Exam 19: Disorders Associated With the Immune System

Which of the following statements about type I reactions is FALSE?

Treatment with certain drugs to reduce transplant rejection can cause

All hypersensitivities involve antibody- antigen reactions.

Which of the following describes a cytotoxic autoimmune reaction?

The process of desensitization to prevent allergies involves the injection of increasing amounts of

Which antibodies will be in the serum of a person with blood type B, Rh+?

Figure 19.1 -In immune complex reaction shown in Figure 19.1, what is the structure labeled "a"?

Explain why a transplant tissue would be rejected if that tissue had different HLAs compared to the HLAs of the recipient. How can this rejection be decreased?

All stem cells are derived from embryonic stem cells.

Which of the following statements about type IV reactions is FALSE?

Attachment of HIV to the target cell depends on

Allergic contact dermatitis is due to

Hemolytic disease of the newborn can result from an

All of the following are false regarding Herceptin EXCEPT

HIV attack of CD4+ T cells causes suppression of both cell- mediated and humoral immune responses.

Which of the following is the least likely vaccine against HIV?

A healthy immune system destroys cancer cells with

Immunodeficiencies are a result of all of the following EXCEPT

Figure 19.1 -In immune complex reaction shown in Figure 19.1, what is the end result of the reaction?

Individuals who do not express CCR5 are highly resistant to infection by HIV.

The Microbial World and You

Chemical Principles

Observing Microorganisms Through a Microscope

Functional Anatomy of Prokaryotic and Eukaryotic Cells

Microbial Metabolism

Microbial Growth

The Control of Microbial Growth

Microbial Genetics

Biotechnology and Recombinant Dna

Classification of Microorganisms

The Prokaryotes: Domains Bacteria and Archaea

The Eukaryotes: Fungi, Algae, Protozoa, and Helminths

Viruses, Viroids, and Prions

Principles of Disease and Epidemiology

Microbial Mechanisms of Pathogenicity

Innate Immunity: Nonspecific Defenses of the Host

Adaptive Immunity: Specific Defenses of the Host

Practical Applications of Immunology

Antimicrobial Drugs

Microbial Diseases of the Skin and Eyes

Microbial Diseases of the Nervous System

Microbial Diseases of the Cardiovascular and Lymphatic Systems

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

Environmental Microbiology

Applied and Industrial Microbiology

Filters

Which antibodies will be in the serum of a person with blood type B, Rh⁺?

HIV attack of CD4⁺T cells causes suppression of both cell- mediated and humoral immune responses.