Exam 12: Amines

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Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s): Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s):

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Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions. Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions.

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Instructions: Classify each of the nitrogen atoms in the compound shown below as primary, secondary, tertiary, or quaternary. Classify: Instructions: Classify each of the nitrogen atoms in the compound shown below as primary, secondary, tertiary, or quaternary. Classify:

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The nitrogen atom in amphetamine is primary.

Instructions: Draw structures corresponding to each of the IUPAC names given in the following question(s). Draw: hexane-1,6-diamine

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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Instructions: Draw structures corresponding to each of the IUPAC names given in the following question(s). Draw:

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In the following series of compounds, which is the most basic and the least basic? Explain your choices. In the following series of compounds, which is the most basic and the least basic? Explain your choices.

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Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s): Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s):

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Which of the following compounds are primary (1 °\degree ) amines?  Which of the following compounds are primary (1 \degree ) amines?

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Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give the major product(s). Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give the major product(s).

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Instructions: Consider the reaction below to answer the following question(s). Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H2/Ni. Instructions: Consider the reaction below to answer the following question(s). Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H<sub>2</sub>/Ni.   Refer to instructions. The synthesis of methamphetamine by reaction of 2-phenyl-2 propanone with methylamine in the presence of H<sub>2</sub>/Ni is referred to as:  a.	reductive nitrogenation b.	reactive nitrogenation c.	reductive amination d.	reactive amination Refer to instructions. The synthesis of methamphetamine by reaction of 2-phenyl-2 propanone with methylamine in the presence of H2/Ni is referred to as: a. reductive nitrogenation b. reactive nitrogenation c. reductive amination d. reactive amination

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Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions. Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions.

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Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s): Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s):

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Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions. Show how each of the following transformations might be best accomplished. More than one step may be required. Show all reagents and all intermediate structures. Refer to instructions.

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Predict the major organic product obtained from the following sequence of reactions. Predict the major organic product obtained from the following sequence of reactions.

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Instructions: Based on the following structures, name the compound. Name: Instructions: Based on the following structures, name the compound. Name:

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Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s): Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry. Give major product(s):

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Instructions: Classify each of the nitrogen atoms in the compound shown below as primary, secondary, tertiary, or quaternary. Classify: Instructions: Classify each of the nitrogen atoms in the compound shown below as primary, secondary, tertiary, or quaternary. Classify:

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Circle any of the following that would be classified as a heterocyclic amine. Circle any of the following that would be classified as a heterocyclic amine.

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Instructions: Consider the reaction below to answer the following question(s). Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H2/Ni. Instructions: Consider the reaction below to answer the following question(s). Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H<sub>2</sub>/Ni.   Refer to instructions. Intermediate A is an example of: Refer to instructions. Intermediate A is an example of:

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