Question 1

In alcoholic fermentation,acetaldehyde is produced by

Accepted Answer

A) the decarboxylation of pyruvate. 
B) the carboxylation of pyruvate. 
C) the decarboxylation of lactate. 
D) the carboxylation of lactate. 
E) none of the above 
A) the decarboxylation of pyruvate. 
B) the carboxylation of pyruvate. 
C) the decarboxylation of lactate. 
D) the carboxylation of lactate. 
E) none of the above

Question 2

Which glycolytic enzyme catalyzes a reaction with an enediolate intermediate?

Accepted Answer

A) phosphoglucomutase 
B) triose phosphate isomerase 
C) phosphofructokinase 
D) aldolase 
E) none of the above 
A) phosphoglucomutase 
B) triose phosphate isomerase 
C) phosphofructokinase 
D) aldolase 
E) none of the above

Question 3

Matching
Choose the correct answer from the list.Not all the answers will be used.

-Glycolysis forms ____ under either aerobic or anaerobic conditions.

Accepted Answer

A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD 
A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD

Question 4

Which enzyme is involved in substrate level phosphorylation in glycolysis?

Accepted Answer

A) Hexokinase 
B) √Pyruvate kinase 
C) Glyceraldehyde-3phosphate dehydrogenase 
D) Aldolase 
E) None of the above. 
A) Hexokinase 
B) √Pyruvate kinase 
C) Glyceraldehyde-3phosphate dehydrogenase 
D) Aldolase 
E) None of the above.

Question 5

Matching
Choose the correct answer from the list.Not all the answers will be used.

-The coenzyme ______ is the oxidizing agent in both aerobic and anaerobic glycolysis.

Accepted Answer

A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD 
A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD

Question 6

Glycolytic synthesis of ATP occurs via

Accepted Answer

A) oxidation. 
B) reduction. 
C) substrate-level phosphorylation. 
D) oxidative phosphorylation. 
E) photophosphorylation. 
A) oxidation. 
B) reduction. 
C) substrate-level phosphorylation. 
D) oxidative phosphorylation. 
E) photophosphorylation.

Question 7

Which of the following enzymes catalyzes the transfer of a phosphoryl group from ATP to glucose?

Accepted Answer

A) hexokinase 
B) phosphoglucose isomerase 
C) glucose-6-phosphatase 
D) phosphoglucose mutase 
E) A transfer such as this does not occur in glycolysis. 
A) hexokinase 
B) phosphoglucose isomerase 
C) glucose-6-phosphatase 
D) phosphoglucose mutase 
E) A transfer such as this does not occur in glycolysis.

Question 8

The reaction below is catalyzed by yeast alcohol dehydrogenase.Which of the following corresponds to X and Y in this reaction?

Accepted Answer

A) X = NADH+ Y = NAD + H+ 
B) X = NAD+ Y = NADH + H+ 
C) X = NADH + H+ Y = NAD+ 
D) X = NAD + H+ Y = NADH+ 
E) X = NADPH + H+ Y = NADP+ 
A) X = NADH+ Y = NAD + H+ 
B) X = NAD+ Y = NADH + H+ 
C) X = NADH + H+ Y = NAD+ 
D) X = NAD + H+ Y = NADH+ 
E) X = NADPH + H+ Y = NADP+

Question 9

Which of the following metabolic conversions is considered to be the major control point of glycolysis?

Accepted Answer

A) fructose-1,6-bisphosphate $\to$ dihydroxyacetone phosphate + glyceraldehyde-3-phosphate 
B) glucose $\to$ glucose-6-phosphate 
C) 2-phosphoglyerate $\to$ phosphoenolpyruvate 
D) fructose-6-phosphate $\to$ fructose-1,6-bisphosphate 
E) phosphoenolpyruvate $\to$ pyruvate 
A) fructose-1,6-bisphosphate $\to$ dihydroxyacetone phosphate + glyceraldehyde-3-phosphate 
B) glucose $\to$ glucose-6-phosphate 
C) 2-phosphoglyerate $\to$ phosphoenolpyruvate 
D) fructose-6-phosphate $\to$ fructose-1,6-bisphosphate 
E) phosphoenolpyruvate $\to$ pyruvate

Question 10

Matching
Choose the correct answer from the list.Not all the answers will be used.

-Vitamin B1 is a component of the coenzyme ______ essential for development of an electron sink necessary for decarboxylation of pyruvate.

Accepted Answer

A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD 
A)  fructose-1,6-bisphosphatase 
B)  pentose phosphate 
C)  pyruvate decarboxylase 
D)  hypoglycemia 
E)  phosphofructokinase
F) NADP+
G) thiamine pyrophosphate
H) ATP
I) galactosemia
J) NAD+
K) fluoride ion
L) pyruvate 
M) glucogenic 
N) FAD

Question 11

The enzymes that catalyze glycolysis are located in the

Accepted Answer

A) endoplasmic reticulum. 
B) mitochondrial matrix. 
C) cytosol. 
D) inner mitochondrial membrane. 
E) outer mitochondrial membrane. 
A) endoplasmic reticulum. 
B) mitochondrial matrix. 
C) cytosol. 
D) inner mitochondrial membrane. 
E) outer mitochondrial membrane.

Question 12

Which of the following best describes the entry of mannose into glycolysis?

Accepted Answer

A) hydrolyzed into two glucose units,they enter normally 
B) phosphorylated at C-1;UMP moiety transferred from UDP-glucose;epimerized at C-2;released from UMP moiety on next transfer as G1P 
C) phosphorylated at C-1;UMP moiety transferred from UDP-glucose;epimerized at C-4;released from UMP moiety on next transfer as G1P 
D) phosphorylated at C-6;epimerized at C-2 to produce G6P 
E) phosphorylated at C-6;isomerized to produce F6P 
A) hydrolyzed into two glucose units,they enter normally 
B) phosphorylated at C-1;UMP moiety transferred from UDP-glucose;epimerized at C-2;released from UMP moiety on next transfer as G1P 
C) phosphorylated at C-1;UMP moiety transferred from UDP-glucose;epimerized at C-4;released from UMP moiety on next transfer as G1P 
D) phosphorylated at C-6;epimerized at C-2 to produce G6P 
E) phosphorylated at C-6;isomerized to produce F6P

Question 13

In which reaction above is at least 1 NADH formed?

Accepted Answer

A) II only 
B) III only 
C) IV only 
D) IV,V 
E) None of the reaction I-V form NADH. 
A) II only 
B) III only 
C) IV only 
D) IV,V 
E) None of the reaction I-V form NADH.

Question 14

The metabolism of mannose requires _____ to produce ____ for entry into the glycolytic pathway.

Accepted Answer

A) hexokinase;glucose-6-phosphate 
B) hexokinase;fructose-6-phosphate 
C) phosphomannose isomerase;glucose-6-phosphate 
D) phosphomannose isomerase;fructose-6-phosphate 
E) phosphofructokinase;bisphosphoglycerate 
A) hexokinase;glucose-6-phosphate 
B) hexokinase;fructose-6-phosphate 
C) phosphomannose isomerase;glucose-6-phosphate 
D) phosphomannose isomerase;fructose-6-phosphate 
E) phosphofructokinase;bisphosphoglycerate

Question 15

During glycolysis,the steps between glucose and formation of the triose phosphates collectively

Accepted Answer

A) consume two ATP and two NADH molecules. 
B) consume two ATP molecules. 
C) produce two ADP and two NADH molecules. 
D) produce two ATP and two NAD+ molecules. 
E) consume two NAD+ molecules. 
A) consume two ATP and two NADH molecules. 
B) consume two ATP molecules. 
C) produce two ADP and two NADH molecules. 
D) produce two ATP and two NAD+ molecules. 
E) consume two NAD+ molecules.

Question 16

The enzyme _____forms a Schiff base upon formation of the enzyme-substrate complex allowing aspartate mediated cleavage of the substrate.

Accepted Answer

A) hexokinase 
B) phosphoglucose isomerase 
C) glucose-6-phosphatase 
D) phosphoglucose mutase 
E) aldolase 
A) hexokinase 
B) phosphoglucose isomerase 
C) glucose-6-phosphatase 
D) phosphoglucose mutase 
E) aldolase

Question 17

If glucose labeled at the C-1 position with 14C passes through glycolysis,on which carbon of pyruvate will the radiolabel be found?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) It will be released in CO2 rather than present in pyruvate. 
E) Not enough information is given to predict. 
A) 1 
B) 2 
C) 3 
D) It will be released in CO2 rather than present in pyruvate. 
E) Not enough information is given to predict.

Question 18

Aerobic glycolysis produces a net yield of ______ ATP.

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
E) more than 4 
A) 1 
B) 2 
C) 3 
D) 4 
E) more than 4

Question 19

Of the reaction types listed below,which type of reaction is NOT used in glycolysis?

Accepted Answer

A) oxidation 
B) phosphorylation 
C) dehydration 
D) isomerization 
E) All are used in glycolysis. 
A) oxidation 
B) phosphorylation 
C) dehydration 
D) isomerization 
E) All are used in glycolysis.

Question 20

In which reaction above is ATP required?

Accepted Answer

A) I,II 
B) II only 
C) III only 
D) IV,V 
E) None of the reactions I-V requires ATP. 
A) I,II 
B) II only 
C) III only 
D) IV,V 
E) None of the reactions I-V requires ATP.

Exam 15: Glucose Catabolism

In alcoholic fermentation,acetaldehyde is produced by

Which glycolytic enzyme catalyzes a reaction with an enediolate intermediate?

Matching Choose the correct answer from the list.Not all the answers will be used. -Glycolysis forms ____ under either aerobic or anaerobic conditions.

Which enzyme is involved in substrate level phosphorylation in glycolysis?

Matching Choose the correct answer from the list.Not all the answers will be used. -The coenzyme ______ is the oxidizing agent in both aerobic and anaerobic glycolysis.

Glycolytic synthesis of ATP occurs via

Which of the following enzymes catalyzes the transfer of a phosphoryl group from ATP to glucose?

The reaction below is catalyzed by yeast alcohol dehydrogenase.Which of the following corresponds to X and Y in this reaction?

Which of the following metabolic conversions is considered to be the major control point of glycolysis?

Matching Choose the correct answer from the list.Not all the answers will be used. -Vitamin B1 is a component of the coenzyme ______ essential for development of an electron sink necessary for decarboxylation of pyruvate.

The enzymes that catalyze glycolysis are located in the

Which of the following best describes the entry of mannose into glycolysis?

In which reaction above is at least 1 NADH formed?

The metabolism of mannose requires _____ to produce ____ for entry into the glycolytic pathway.

During glycolysis,the steps between glucose and formation of the triose phosphates collectively

The enzyme _____forms a Schiff base upon formation of the enzyme-substrate complex allowing aspartate mediated cleavage of the substrate.

If glucose labeled at the C-1 position with 14C passes through glycolysis,on which carbon of pyruvate will the radiolabel be found?

Aerobic glycolysis produces a net yield of ______ ATP.

Of the reaction types listed below,which type of reaction is NOT used in glycolysis?

In which reaction above is ATP required?

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Introduction to Metabolism

Glycogen Metabolism and Gluconeogenesis

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

Nucleic Acid Structure

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

Matching Choose the correct answer from the list.Not all the answers will be used. -Vitamin B₁ is a component of the coenzyme ______ essential for development of an electron sink necessary for decarboxylation of pyruvate.

The metabolism of mannose requires _ to produce for entry into the glycolytic pathway.

If glucose labeled at the C-1 position with ¹⁴C passes through glycolysis,on which carbon of pyruvate will the radiolabel be found?