Exam 15: Glucose Catabolism

Matching Choose the correct answer from the list.Not all the answers will be used. -______ is an inhibitor of enolase which was useful in elucidating the glycolytic pathway.

Which of the following compounds contains a "high-energy" bond and is used to produce ATP by substrate-level phosphorylation in glycolysis?

Which of the following reactions does not occur in mammals?

Matching Choose the correct answer from the list.Not all the answers will be used. -NADPH used in lipid biosynthesis is produced by the ______ pathway.

Individuals with galactosemia

In which of the following metabolic conversions is ATP required during glycolysis? (I)fructose-6-phosphate SYMBOL 174 \f "Symbol" fructose-1,6-bisphosphate (II)glucose SYMBOL 174 \f "Symbol" glucose-6-phosphate (III)fructose-1,6-bisphosphate SYMBOL 174 \f "Symbol" dihydroxyacetone phosphate + glyceraldehyde-3-phosphate (IV)glucose-6-phosphate SYMBOL 174 \f "Symbol" fructose-6-phosphate

The reaction catalyzed by the enzyme aldolase has a $\Delta$ G˚' ≈ +23 kJ/mol.In muscle cells,the reaction proceeds in this same,forward direction.How can this occur?

Phosphofructokinase is allosterically _____ by high concentrations of _____. (I)activated;ATP (II)inhibited;ATP (III)inhibited;fructose-2,6-bisphosphate (IV)activated;fructose -2,6-bisphosphate

Glucose is converted to ______ in skeletal muscle under anaerobic conditions.

Which of the following is correct regarding the hexose monophosphate shunt? (I)NADH is generated by the oxidation of glucose-6-phosphate. (II)Glyceraldehyde-3-phosphate is generated in the reaction. (III)The pathway requires a transaldolase. (IV)The pathway generates 3 ATP per 1 glucose-6-phosphate.

Matching Choose the correct answer from the list.Not all the answers will be used. -The products of glycolysis include: ATP,NADH,and ______.

Conversion of galactose to glucose (I)requires an epimerase. (II)requires uridine diphosphate. (III)requires a transferase (IV)requires an isomerase.

Methanol is highly toxic,not because of its own activity,but because it is converted metabolically into formaldehyde,which is the actual poison.What enzyme catalyzes this conversion?

Which of the following best explains why an enzyme hasn't evolved to catalyze the following reaction as the first step of glycolysis? Glucose + P_i -> glucose-6-phosphate (I)The use of ATP is required for this step to serve as a regulatory control point. (II)The use of ATP is important because it helps keep its concentration low.Otherwise the high [ATP] would slow glycolysis too much through feedback inhibition. (III)The large positive $\Delta$ G˚' of this reaction would need to be overcome by an exceedingly high [P_i]. (IV)Inorganic phosphate cannot be specifically placed on the carbon in the 6^th position.

The utilization of fructose in glycolysis in the liver

Matching Choose the correct answer from the list.Not all the answers will be used. -A genetic deficiency of a single transferase enzyme required for sugar group exchange causes the medical condition known as _____ which results in failure to thrive,mental retardation,and potential liver damage.

Which of the following is true regarding glycolysis? (I)There is a net oxidation of substrate carbon atoms. (II)There is no net release of free energy. (III)Pyruvate is generated only during aerobic glycolysis. (IV)There is 2 ATP formed for every 2 glucose molecules. )

Consider the following portion of the glycolytic sequence catalyzed by the enzymes above the arrows.Which products(s)will produce ATP?

Which is the net equation for aerobic glycolysis?

Select the enzyme from the list which would catalyze the reaction shown below.