Question 1

Matching
Choose the correct answer from the list.Not all the answers will be used.

-______ activates glycogen breakdown.

Accepted Answer

A)  phosphorylase a 
B)  gluconeogenesis 
C)  glucagon 
D)  glucose-6-phosphatase 
E)  cAMP
F)  biotin
G)  insulin
H) glycogenolysis
I) liver
J) glucose-1-phosphate
K) dolichol
L) muscle 
A)  phosphorylase a 
B)  gluconeogenesis 
C)  glucagon 
D)  glucose-6-phosphatase 
E)  cAMP
F)  biotin
G)  insulin
H) glycogenolysis
I) liver
J) glucose-1-phosphate
K) dolichol
L) muscle

Question 2

Which of the following enzymes directly converts phosphorylase b into the more active form,phosphorylase a?

Accepted Answer

A) cAMP-dependent protein kinase 
B) phosphorylase kinase 
C) protein kinase A 
D) adenylate cyclase 
E) phosphoprotein phosphatase-1 
A) cAMP-dependent protein kinase 
B) phosphorylase kinase 
C) protein kinase A 
D) adenylate cyclase 
E) phosphoprotein phosphatase-1

Question 3

Increased levels of epinephrine in the blood will
(I)activate adenylate cyclase in liver and muscle cells.
(II)stimulate glycogen synthesis.
(III)inhibit glycolysis in the muscle cell.
(IV)stimulate gluconeogenesis in the muscle cell.

Accepted Answer

A) I only 
B) I,II 
C) I,II,III 
D) II only 
E) I,II,III,IV 
A) I only 
B) I,II 
C) I,II,III 
D) II only 
E) I,II,III,IV

Question 4

Which of the following is true regarding the reaction shown below?
Pyruvate + HCO3− + ATP $\to$ oxaloacetate + ADP + Pi
(I)It requires the direct transport of oxaloacetate across the membrane.
(II)It utilizes the malate-aspartate shuttle in some species.
(III)It is essential for gluconeogenesis.
(IV)Its reactants require the function of enzymes which are only found in the cytosol.

Accepted Answer

A) I only 
B) II,III 
C) II,III,IV 
D) III only 
E) II,IV 
A) I only 
B) II,III 
C) II,III,IV 
D) III only 
E) II,IV

Question 5

Which statement is TRUE concerning the metabolic reaction shown below?

Accepted Answer

A) The enzyme that catalyzes this reaction is called a mutase. 
B) The enzyme that catalyzes this reaction is called a kinase. 
C) This reaction requires the free energy of ATP hydrolysis. 
D) This reaction requires multiple steps catalyzed by a phosphorylase and a mutase. 
E) The oxidation level of glucose-1-phosphate is higher than that of glucose-6-phosphate. 
A) The enzyme that catalyzes this reaction is called a mutase. 
B) The enzyme that catalyzes this reaction is called a kinase. 
C) This reaction requires the free energy of ATP hydrolysis. 
D) This reaction requires multiple steps catalyzed by a phosphorylase and a mutase. 
E) The oxidation level of glucose-1-phosphate is higher than that of glucose-6-phosphate.

Question 6

Which of the following is correct concerning the metabolic reaction shown below?
Pyruvate + CO2 + ATP SYMBOL 174 \f "Symbol" oxaloacetate + ADP + Pi
(I)This metabolic reaction is catalyzed by pyruvate carboxykinase.
(II)The enzyme that catalyzes this reaction is activated by high concentrations of acetyl-CoA .
(III)The enzyme that catalyzes this reaction is covalently bonded to the coenzyme pyridoxal-5ꞌ-phosphate.
(IV)The enzyme that catalyzes this reaction is located in the endoplasmic reticulum of the cell .

Accepted Answer

A) I,II 
B) I only 
C) II only 
D) II,III 
E) II,III,IV 
A) I,II 
B) I only 
C) II only 
D) II,III 
E) II,III,IV

Question 7

Individuals with McArdle's disease lack the ____ in the ____,

Accepted Answer

A) debranching enzyme;liver 
B) phosphoglucomutase;liver 
C) glycogen phosphorylase;muscle 
D) phosphoglucomutase;muscle 
E) glycogen phosphorylase;liver 
A) debranching enzyme;liver 
B) phosphoglucomutase;liver 
C) glycogen phosphorylase;muscle 
D) phosphoglucomutase;muscle 
E) glycogen phosphorylase;liver

Question 8

What molecules correspond to correspond to X and Y in the following gluconeogenic reaction?
Fructose-1,6-bisphosphotase + X $\to$ Fructose-6-phosphate + Y

Accepted Answer

A) X = NADH + H+ Y = NAD+ 
B) X = ATP Y = ADP + Pi 
C) X = NAD+ Y = NADH + H+ 
D) X = GTP Y = GTP + Pi 
E) X = H2O Y = Pi 
A) X = NADH + H+ Y = NAD+ 
B) X = ATP Y = ADP + Pi 
C) X = NAD+ Y = NADH + H+ 
D) X = GTP Y = GTP + Pi 
E) X = H2O Y = Pi

Question 9

The synthesis of N-linked oligosaccharides occur in the _____ while O-linked oligosaccharides are synthesized in the ______.

Accepted Answer

A) Golgi apparatus;endoplasmic reticulum 
B) cytosol;Golgi apparatus 
C) mitochondrial matrix;endoplasmic reticulum 
D) endoplasmic reticulum;Golgi apparatus 
E) Golgi apparatus;mitochondrial matrix 
A) Golgi apparatus;endoplasmic reticulum 
B) cytosol;Golgi apparatus 
C) mitochondrial matrix;endoplasmic reticulum 
D) endoplasmic reticulum;Golgi apparatus 
E) Golgi apparatus;mitochondrial matrix

Question 10

The biotin prosthetic group of pyruvate carboxylase is covalently attached to a ______ residue of the enzyme?

Accepted Answer

A) valine 
B) serine 
C) lysine 
D) arginine 
E) the biotin is attached non-covalently 
A) valine 
B) serine 
C) lysine 
D) arginine 
E) the biotin is attached non-covalently

Matching Choose the correct answer from the list.Not all the answers will be used. -______ activates glycogen breakdown.

Which of the following enzymes directly converts phosphorylase b into the more active form,phosphorylase a?

Increased levels of epinephrine in the blood will (I)activate adenylate cyclase in liver and muscle cells. (II)stimulate glycogen synthesis. (III)inhibit glycolysis in the muscle cell. (IV)stimulate gluconeogenesis in the muscle cell.

Which statement is TRUE concerning the metabolic reaction shown below?

Individuals with McArdle's disease lack the in the ,

What molecules correspond to correspond to X and Y in the following gluconeogenic reaction? Fructose-1,6-bisphosphotase + X $\to$ Fructose-6-phosphate + Y

The synthesis of N-linked oligosaccharides occur in the _ while O-linked oligosaccharides are synthesized in the __.

The biotin prosthetic group of pyruvate carboxylase is covalently attached to a ______ residue of the enzyme?

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Introduction to Metabolism

Glucose Catabolism

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

Nucleic Acid Structure

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

Exam 16: Glycogen Metabolism and Gluconeogenesis

Matching Choose the correct answer from the list.Not all the answers will be used. -______ activates glycogen breakdown.

Which of the following enzymes directly converts phosphorylase b into the more active form,phosphorylase a?

Increased levels of epinephrine in the blood will (I)activate adenylate cyclase in liver and muscle cells. (II)stimulate glycogen synthesis. (III)inhibit glycolysis in the muscle cell. (IV)stimulate gluconeogenesis in the muscle cell.

Which statement is TRUE concerning the metabolic reaction shown below?

Individuals with McArdle's disease lack the ____ in the ____,

What molecules correspond to correspond to X and Y in the following gluconeogenic reaction? Fructose-1,6-bisphosphotase + X →\to→ Fructose-6-phosphate + Y

The synthesis of N-linked oligosaccharides occur in the _____ while O-linked oligosaccharides are synthesized in the ______.

The biotin prosthetic group of pyruvate carboxylase is covalently attached to a ______ residue of the enzyme?

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Introduction to Metabolism

Glucose Catabolism

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

Nucleic Acid Structure

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

Individuals with McArdle's disease lack the in the ,

What molecules correspond to correspond to X and Y in the following gluconeogenic reaction? Fructose-1,6-bisphosphotase + X $\to$ Fructose-6-phosphate + Y

The synthesis of N-linked oligosaccharides occur in the _ while O-linked oligosaccharides are synthesized in the __.