Question 1

All hypersensitivities involve antibody-antigen reactions.

Accepted Answer

A) True 
 B)False

Question 2

All of the following are true of hypersensitivity EXCEPT

Accepted Answer

A) it occurs in the presence of an antigen. 
B) it is synonymous with "allergy." 
C) it occurs when an individual is exposed to an allergen for the first time. 
D) it is due to an altered immune response. 
E) it requires previous exposure to an antigen. 
A) it occurs in the presence of an antigen. 
B) it is synonymous with "allergy." 
C) it occurs when an individual is exposed to an allergen for the first time. 
D) it is due to an altered immune response. 
E) it requires previous exposure to an antigen.

Question 3

Which of the terms regarding treatments after transplantation of an organ is mismatched?

Accepted Answer

A) cyclosporine-suppression of B cells. 
B) cyclosporine- kidney toxicity. 
C) sirolimus-inhibit cell mediated and humoral immunity. 
D) basiliximab-chimeric monoclonal. 
E) tacrolimus-suppression of IL-2 secretion. 
A) cyclosporine-suppression of B cells. 
B) cyclosporine- kidney toxicity. 
C) sirolimus-inhibit cell mediated and humoral immunity. 
D) basiliximab-chimeric monoclonal. 
E) tacrolimus-suppression of IL-2 secretion.

Question 4

Graft-versus-host disease will most likely be a complication of a(n)

Accepted Answer

A) skin graft. 
B) bone marrow transplant. 
C) blood transfusion. 
D) Rh incompatibility between mother and fetus. 
E) corneal transplant. 
A) skin graft. 
B) bone marrow transplant. 
C) blood transfusion. 
D) Rh incompatibility between mother and fetus. 
E) corneal transplant.

Question 5

Differentiate type II from type III hypersensitivity reactions.

Accepted Answer

Type II and Type III hypersensitivity re

Question 6

Which of the following statements about type IV reactions is FALSE?

Accepted Answer

A) Reactions are primarily due to T cell proliferation. 
B) Reactions are not apparent for a day or more. 
C) Cytokines initiate tissue damage. 
D) Allergic contact dermatitis is an example. 
E) Hemolytic disease of the newborn is an example. 
A) Reactions are primarily due to T cell proliferation. 
B) Reactions are not apparent for a day or more. 
C) Cytokines initiate tissue damage. 
D) Allergic contact dermatitis is an example. 
E) Hemolytic disease of the newborn is an example.

Question 7

Figure 19.1
  
-In immune complex reaction shown in Figure 19.1,what is the end result of the reaction?

Accepted Answer

A) IgG is directed against cell membrane antigens. 
B) Complement is activated. 
C) Neutrophils are attracted and release enzymes. 
D) Endothelial cells are damaged. 
E) Antibodies destroy neutrophils. 
A) IgG is directed against cell membrane antigens. 
B) Complement is activated. 
C) Neutrophils are attracted and release enzymes. 
D) Endothelial cells are damaged. 
E) Antibodies destroy neutrophils.

Question 8

Vaccines against HIV have proven to be very effective in halting the spread of disease.

Accepted Answer

A) True 
 B)False

Question 9

Hemolytic disease of the newborn can result from an

Accepted Answer

A) Rh⁺ mother with an Rh⁻ fetus. 
B) Rh⁻ mother with an Rh⁺ fetus. 
C) AB mother with a B fetus. 
D) AB mother with an O fetus. 
E) Rh⁻ mother and an A fetus. 
A) Rh⁺ mother with an Rh⁻ fetus. 
B) Rh⁻ mother with an Rh⁺ fetus. 
C) AB mother with a B fetus. 
D) AB mother with an O fetus. 
E) Rh⁻ mother and an A fetus.

Question 10

A health care worker had a needlestick injury while drawing blood from an AIDS patient.Lab tests on the worker's serum were negative.Explain why the worker can still be infected even though her lab tests were negative.How should her health care be monitored?

Accepted Answer

The worker can still be infected with HI

Question 11

Which of the following describes a cytotoxic autoimmune reaction?

Accepted Answer

A) Antibodies react to cell-surface antigens. 
B) Antibodies are not made. 
C) Cells are killed. 
D) Immune complexes form. 
E) Mediated by T cells. 
A) Antibodies react to cell-surface antigens. 
B) Antibodies are not made. 
C) Cells are killed. 
D) Immune complexes form. 
E) Mediated by T cells.

Question 12

All of the following lead to drug-induced thrombocytopenic purpura.Which occurs first?

Accepted Answer

A) Antibodies and complement react with platelets. 
B) Antibodies against haptens are formed. 
C) Drug binds to platelets. 
D) Platelets are destroyed. 
E) Purpura occurs on the skin. 
A) Antibodies and complement react with platelets. 
B) Antibodies against haptens are formed. 
C) Drug binds to platelets. 
D) Platelets are destroyed. 
E) Purpura occurs on the skin.

Question 13

Table 19.1
 $$\begin{array} { | l | l | } 
\hline \text { Donor } & \text { Recipient } \
\hline \text { 1. } \mathrm { AB } ^ { \mathrm { B } } \mathrm { Rh } ^ { - } & \mathrm { AB } , \mathrm { Rh } ^ { + } \
\hline \text { 2. } \mathrm { A } , \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { - } \
\hline \text { 3. } \mathrm { A } ^ { + } \mathrm { Rh } ^ { + } & \mathrm { O } , \mathrm { Rh } ^ { + } \
\hline \text { 4. } \mathrm { B } , \mathrm { Rh } ^ { - } & \mathrm { B } , \mathrm { Rh } ^ { + } \
\hline \text { 5. } \mathrm { B } , \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { + } \
\hline
\end{array}$$
Which blood transfusions in Table 19.1 are incompatible?

Accepted Answer

A) 2 and 5 
B) 1,2,and 3 
C) 2,3,and 5 
D) 3 and 4 
E) 1 and 2 
A) 2 and 5 
B) 1,2,and 3 
C) 2,3,and 5 
D) 3 and 4 
E) 1 and 2

Question 14

The reasons for investigating stem cells to replace damaged organs and tissues in a patient include all of the following EXCEPT

Accepted Answer

A) the patient will not reject tissues produced with their stem cells. 
B) adult stem cells can be successfully induced to develop into some specifically needed cell types. 
C) embryonic stem cells can be coaxed into developing into any cell type in the body. 
D) umbilical cord blood cells are less likely to cause GVHD than adult stem cell grafts. 
E) pluripotent stem cells naturally occur even late in life in mammals. 
A) the patient will not reject tissues produced with their stem cells. 
B) adult stem cells can be successfully induced to develop into some specifically needed cell types. 
C) embryonic stem cells can be coaxed into developing into any cell type in the body. 
D) umbilical cord blood cells are less likely to cause GVHD than adult stem cell grafts. 
E) pluripotent stem cells naturally occur even late in life in mammals.

Question 15

When testing donated blood for compatibility you would find a person with O type blood

Accepted Answer

A) has O type antigens on their red blood cells. 
B) will lack plasma antibodies to A and B type antigens. 
C) will lack A and B red blood cell antigens. 
D) lacks HLA and MHC antigens. 
E) will have anti-O antibodies in their plasma. 
A) has O type antigens on their red blood cells. 
B) will lack plasma antibodies to A and B type antigens. 
C) will lack A and B red blood cell antigens. 
D) lacks HLA and MHC antigens. 
E) will have anti-O antibodies in their plasma.

Question 16

An inherited immunodeficiency is termed ________ and a secondary immunodeficiency is also known as ________.

Accepted Answer

A) congenital;acquired 
B) birth defect;inherited 
C) dysgenesis;congenital 
D) aplasia;SCID 
E) immune syndrome;lymphoma 
A) congenital;acquired 
B) birth defect;inherited 
C) dysgenesis;congenital 
D) aplasia;SCID 
E) immune syndrome;lymphoma

Question 17

Xenotransplantation is an effective alternative to using isografts.

Accepted Answer

A) True 
 B)False

Question 18

Symptoms of delayed cell-mediated reactions are due to

Accepted Answer

A) IgE antibodies. 
B) neutrophils. 
C) cytokines. 
D) IgG antibodies. 
E) antigens. 
A) IgE antibodies. 
B) neutrophils. 
C) cytokines. 
D) IgG antibodies. 
E) antigens.

Question 19

Skin tests are reliable indicators for the diagnosis of food-related allergies.

Accepted Answer

A) True 
 B)False

Question 20

Which of the following statements is true of phase 3 HIV infection?

Accepted Answer

A) HIV in blood stabilizes at 1000-10,000 per ml of blood. 
B) CD4⁺ cell population drops to less than 200 cells per μl of blood. 
C) HIV peaks to 10 million per ml of blood. 
D) asymptomatic infection. 
E) Seroconversion occurs. 
A) HIV in blood stabilizes at 1000-10,000 per ml of blood. 
B) CD4⁺ cell population drops to less than 200 cells per μl of blood. 
C) HIV peaks to 10 million per ml of blood. 
D) asymptomatic infection. 
E) Seroconversion occurs.

Exam 19: Disorders Associated With the Immune System

All hypersensitivities involve antibody-antigen reactions.

All of the following are true of hypersensitivity EXCEPT

Which of the terms regarding treatments after transplantation of an organ is mismatched?

Graft-versus-host disease will most likely be a complication of a(n)

Differentiate type II from type III hypersensitivity reactions.

Which of the following statements about type IV reactions is FALSE?

Figure 19.1 -In immune complex reaction shown in Figure 19.1,what is the end result of the reaction?

Vaccines against HIV have proven to be very effective in halting the spread of disease.

Hemolytic disease of the newborn can result from an

A health care worker had a needlestick injury while drawing blood from an AIDS patient.Lab tests on the worker's serum were negative.Explain why the worker can still be infected even though her lab tests were negative.How should her health care be monitored?

Which of the following describes a cytotoxic autoimmune reaction?

All of the following lead to drug-induced thrombocytopenic purpura.Which occurs first?

Table 19.1 Donor Recipient 1. , 2. , , 3. , 4. , , 5. , , Which blood transfusions in Table 19.1 are incompatible?

The reasons for investigating stem cells to replace damaged organs and tissues in a patient include all of the following EXCEPT

When testing donated blood for compatibility you would find a person with O type blood

An inherited immunodeficiency is termed ________ and a secondary immunodeficiency is also known as ________.

Xenotransplantation is an effective alternative to using isografts.

Symptoms of delayed cell-mediated reactions are due to

Skin tests are reliable indicators for the diagnosis of food-related allergies.

Which of the following statements is true of phase 3 HIV infection?

The Microbial World and You

Chemical Principles

Observing Microorganisms Through a Microscope

Functional Anatomy of Prokaryotic and Eukaryotic

Microbial Metabolism

Microbial Growth

The Control of Microbial Growth

Microbial Genetics

Biotechnology and Dna Technology

Classification of Microorganisms

The Prokaryotes: Domains Bacteria and Archaea

The Eukaryotes: Fungi, algae, protozoa, and Helminths

Viruses,viroids,and Prions

Principles of Disease and Epidemiology

Microbial Mechanisms of Pathogenicity

Innate Immunity: Nonspecific Defenses of the Host

Adaptive Immunity: Specific Defenses of the Host

Practical Applications of Immunology

Antimicrobial Drugs

Microbial Diseases of the Skin and Eyes

Microbial Diseases of the Nervous System

Microbial Diseases of the Cardiovascular and Lymphatic Systems

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

Environmental Microbiology

Applied and Industrial Microbiology

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An inherited immunodeficiency is termed and a secondary immunodeficiency is also known as .