Question 1

Maturation of stem cells into mature blood cells occurs in the red bone marrow.

Accepted Answer

A) True 
 B)False

Question 2

All of the following are iron-binding proteins found in humans EXCEPT

Accepted Answer

A) lactoferrin. 
B) transferrin. 
C) hemoglobin. 
D) siderophorin. 
E) ferritin. 
A) lactoferrin. 
B) transferrin. 
C) hemoglobin. 
D) siderophorin. 
E) ferritin.

Question 3

Each of the following is an effect of complement activation EXCEPT

Accepted Answer

A) interference with viral replication. 
B) bacterial cell lysis. 
C) opsonization. 
D) increased phagocytic activity. 
E) increased blood vessel permeability. 
A) interference with viral replication. 
B) bacterial cell lysis. 
C) opsonization. 
D) increased phagocytic activity. 
E) increased blood vessel permeability.

Question 4

Which one of the following is a regulatory protein that prevents the assembly of C9 molecules in the complement cascade,effectively shutting down MAC production?

Accepted Answer

A) C3b 
B) properdin 
C) C3a 
D) C3a receptor 
E) CD59 
A) C3b 
B) properdin 
C) C3a 
D) C3a receptor 
E) CD59

Question 5

Iron is an important item for the growth of microorganisms in a pathogenic state in the human body.Describe two ways in which bacteria might attempt to obtain iron from human cells or tissues for their own use.Then,describe a way in which this bacterial iron-scavenging might be disrupted without harming the human cells/tissues in the process.

Accepted Answer

There are two main ways in which bacteri

Question 6

All of the following are true regarding NK cells EXCEPT

Accepted Answer

A) they are a type of lymphocyte. 
B) they are found in tissues of the lymphatic system. 
C) they have the ability to kill infected body cells and some tumor cells. 
D) they destroy infected body cells by phagocytosis. 
E) they release toxic substances that cause cell lysis or apoptosis. 
A) they are a type of lymphocyte. 
B) they are found in tissues of the lymphatic system. 
C) they have the ability to kill infected body cells and some tumor cells. 
D) they destroy infected body cells by phagocytosis. 
E) they release toxic substances that cause cell lysis or apoptosis.

Question 7

Innate immunity

Accepted Answer

A) is slower than adaptive immunity in responding to pathogens. 
B) is nonspecific and present at birth. 
C) involves a memory component. 
D) involves T cells and B cells. 
E) provides increased susceptibility to disease. 
A) is slower than adaptive immunity in responding to pathogens. 
B) is nonspecific and present at birth. 
C) involves a memory component. 
D) involves T cells and B cells. 
E) provides increased susceptibility to disease.

Question 8

Which of the following is found normally in serum?

Accepted Answer

A) complement 
B) interferon 
C) histamine 
D) leukocytosis-promoting factor 
E) TLRs 
A) complement 
B) interferon 
C) histamine 
D) leukocytosis-promoting factor 
E) TLRs

Question 9

The dermis is composed of connective tissue and serves the primary purpose of providing direct protection from the external environment.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following statements about fixed macrophages is FALSE?

Accepted Answer

A) They are found in certain tissues and organs. 
B) They develop from neutrophils. 
C) They are cells of the mononuclear phagocytic system. 
D) They are mature monocytes. 
E) They gather at sites of infection. 
A) They are found in certain tissues and organs. 
B) They develop from neutrophils. 
C) They are cells of the mononuclear phagocytic system. 
D) They are mature monocytes. 
E) They gather at sites of infection.

Question 11

All of the following are effects of histamine EXCEPT

Accepted Answer

A) vasodilation. 
B) fever. 
C) swelling. 
D) redness. 
E) pain. 
A) vasodilation. 
B) fever. 
C) swelling. 
D) redness. 
E) pain.

Question 12

Aspirin alleviates pain,inflammation,and fever by inhibiting prostaglandins.

Accepted Answer

A) True 
 B)False

Question 13

Phagocytes utilize all of the following to optimize interaction with (getting to and getting hold of)microorganisms EXCEPT

Accepted Answer

A) trapping a bacterium against a rough surface. 
B) opsonization. 
C) chemotaxis. 
D) lysozyme. 
E) complement. 
A) trapping a bacterium against a rough surface. 
B) opsonization. 
C) chemotaxis. 
D) lysozyme. 
E) complement.

Question 14

Histamine and kinins cause increased blood flow and capillary permeability.

Accepted Answer

A) True 
 B)False

Question 15

All of the following are part of the mechanism of action of alpha and beta interferons EXCEPT

Accepted Answer

A) they bind to the surface of uninfected cells. 
B) they are effective for long periods. 
C) they initiate manufacture of antiviral proteins. 
D) they disrupt stages of viral multiplication. 
E) they initiate transcription. 
A) they bind to the surface of uninfected cells. 
B) they are effective for long periods. 
C) they initiate manufacture of antiviral proteins. 
D) they disrupt stages of viral multiplication. 
E) they initiate transcription.

Question 16

Each of the following provides protection from phagocytic digestion EXCEPT

Accepted Answer

A) M protein. 
B) capsules. 
C) formation of phagolysosomes. 
D) leukocidins. 
E) biofilms. 
A) M protein. 
B) capsules. 
C) formation of phagolysosomes. 
D) leukocidins. 
E) biofilms.

Question 17

Chronic inflammation can result in a(n)________,which can cause impairment of normal tissue function.

Accepted Answer

A) abscess 
B) fever 
C) scar tissue/fibrosis 
D) parenchyma 
E) blood clot 
A) abscess 
B) fever 
C) scar tissue/fibrosis 
D) parenchyma 
E) blood clot

Question 18

Macrophages arise from which of the following?

Accepted Answer

A) basophils 
B) eosinophils 
C) lymphocytes 
D) monocytes 
E) neutrophils 
A) basophils 
B) eosinophils 
C) lymphocytes 
D) monocytes 
E) neutrophils

Question 19

The antimicrobial effects of AMPs include all of the following EXCEPT

Accepted Answer

A) inhibition of cell wall synthesis. 
B) lysis of bacterial cells. 
C) destruction of nucleic acids. 
D) pore formation in bacterial membranes. 
E) inhibition of phagocytosis. 
A) inhibition of cell wall synthesis. 
B) lysis of bacterial cells. 
C) destruction of nucleic acids. 
D) pore formation in bacterial membranes. 
E) inhibition of phagocytosis.

Question 20

An example of a TLR would be peptidoglycan found in the cell wall of gram-positive bacteria.

Accepted Answer

A) True 
 B)False

Exam 16: Innate Immunity: Nonspecific Defenses of the Host

Maturation of stem cells into mature blood cells occurs in the red bone marrow.

All of the following are iron-binding proteins found in humans EXCEPT

Each of the following is an effect of complement activation EXCEPT

Which one of the following is a regulatory protein that prevents the assembly of C9 molecules in the complement cascade,effectively shutting down MAC production?

All of the following are true regarding NK cells EXCEPT

Innate immunity

Which of the following is found normally in serum?

The dermis is composed of connective tissue and serves the primary purpose of providing direct protection from the external environment.

Which of the following statements about fixed macrophages is FALSE?

All of the following are effects of histamine EXCEPT

Aspirin alleviates pain,inflammation,and fever by inhibiting prostaglandins.

Phagocytes utilize all of the following to optimize interaction with (getting to and getting hold of)microorganisms EXCEPT

Histamine and kinins cause increased blood flow and capillary permeability.

All of the following are part of the mechanism of action of alpha and beta interferons EXCEPT

Each of the following provides protection from phagocytic digestion EXCEPT

Chronic inflammation can result in a(n)________,which can cause impairment of normal tissue function.

Macrophages arise from which of the following?

The antimicrobial effects of AMPs include all of the following EXCEPT

An example of a TLR would be peptidoglycan found in the cell wall of gram-positive bacteria.

The Microbial World and You

Chemical Principles

Observing Microorganisms Through a Microscope

Functional Anatomy of Prokaryotic and Eukaryotic

Microbial Metabolism

Microbial Growth

The Control of Microbial Growth

Microbial Genetics

Biotechnology and Dna Technology

Classification of Microorganisms

The Prokaryotes: Domains Bacteria and Archaea

The Eukaryotes: Fungi, algae, protozoa, and Helminths

Viruses,viroids,and Prions

Principles of Disease and Epidemiology

Microbial Mechanisms of Pathogenicity

Adaptive Immunity: Specific Defenses of the Host

Practical Applications of Immunology

Disorders Associated With the Immune System

Antimicrobial Drugs

Microbial Diseases of the Skin and Eyes

Microbial Diseases of the Nervous System

Microbial Diseases of the Cardiovascular and Lymphatic Systems

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

Environmental Microbiology

Applied and Industrial Microbiology

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