Exam 16: Blood

Mike has classical hemophilia, a clotting disorder, but his case is considered "mild." Contrary to popular belief, Mike doesn't usually have problematic bleeding episodes related to cutting himself; a more severe problem for him would be brought on by a sprained ankle or by having a full body impact, like falling off a horse and landing hard on the ground, injuries considered "closed." With what you have learned about blood coagulation, can you explain how this could be so? Assuming Mike is lacking factor VIII, which pathways does he depend on?

________ regulates the growth and maturation of megakaryocytes.

Which of the following is/are vasoconstrictors?

The process of red blood cell production is called

The primary organ where erythropoietin is produced is the

The function of red blood cells is to

The total volume of blood in the body of a 70-kg man is approximately ________ liters.

What is jaundice? What substance is present in abnormal levels? What can cause jaundice to occur? What difference may impede a doctor's ability to diagnose jaundice between people of European compared to African ancestry?

Each red blood cell is shaped as a biconcave disk.This allows it to

A dead human body has been discovered in the woods near your home.No, you are not a homicide suspect; rather you are an expert hematologist, and the body is still warm.Implausibly, this adult corpse has no gender cues (no sexual organs, and skeletal features that are in between those expected for males or females).How can you assist the detectives in determining the gender of this person, using the hematology lab in your garage?

The usual treatment for neonatal jaundice is exposing the infant to certain wavelengths of light.The infant wears only a diaper and undergoes the light treatment continuously for several days, even at night.Why can the infant's treatment then be discontinued?

List any five nutrients important for blood cell synthesis and briefly explain the role of each.

The percentage of cells in blood-producing tissues that become white blood cells is about ________%.

A study was done in 1998 by Dr.Benjamin Levine to explore the role of altitude training in athletic performance.First he trained athletes at low altitude, then measured their finish times in a 5 kilometer run.Then the athletes were placed into one of the following groups: I, living and training at high altitude; II, living at high altitude and training at low; or III, living and training at low altitude.The athletes were then retested in another low-altitude 5 K race.In this study, what are the control and experimental data? What are the dependent and independent variables? The results are expressed as average change in speed of each group.I: -3.4 sec., II: +13.4 sec., III: -26.7 sec.Graph and interpret the results.Did the results surprise you? Why or why not? Propose some explanations for the lower performance by the live high-train high group.Why wasn't there a live low-train high group?

The growth and maturation of megakaryocytes is regulated by the glycoprotein ________.

________, ________, and ________ are called granulocytes because ________.

Red blood cells in the circulation live for about ________.The short life span is due to ________.

A normal adult hematocrit would be approximately ________%.

The common pathway of coagulation begins with the

Platelets function in