Exam 15: The Plasma Membrane

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The currently accepted model of membrane structure, proposed by Singer and Nicolson, is called the _______ model.

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Coated pits are converted to coated vesicles by formation of rings of the protein

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Phosphatidylcholine is the only major phospholipid in the plasma membrane.

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According to the generally accepted fluid mosaic model of membrane structure, membranes are two-dimensional fluids through which proteins can move freely in lateral directions. Provide an example of a membrane protein that is not free to move laterally within a plasma membrane.

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The resting potential of a typical eukaryotic cell is _______ mV.

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Gene therapy for cystic fibrosis involves transfer of the _______ gene into bronchial epithelia.

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Which of the following features of a membrane protein is never used as a membrane anchor?

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Transport of glucose into the intestinal epithelium is driven by ion gradients established by the

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Facilitated diffusion is a lipid-mediated process.

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How does the plasma membrane come to be hyperpolarized locally during action potential reversal?

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Frye and Edidin demonstrated the mobility of membrane proteins with the use of fused human and mouse cells. Briefly describe the results of their experiment.

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The major ATPase maintaining the plasma membrane potential is the Na+-K+ pump.

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Clusters of sphingolipids, cholesterol, and membrane proteins that move together laterally in the plane of the plasma membrane are called lipid

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The plasma membrane of intestinal epithelial cells is divided into two domains: the _______ domain and the _______ domain.

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Phagocytosis is an example of macropinocytosis.

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What would be the resting potential across an artificial membrane if all charged molecules on both sides were equally permeable?

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Molecules that diffuse passively across the plasma membrane most rapidly are

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Active transport is transport in an energetically

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The drug ouabain inhibits the plasma membrane Na+-K+ pump. Why does it also inhibit glucose transport across the intestinal epithelial layer?

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Plasma membrane phospholipids are

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