Question 1

Where is clathrin located in cells?

Accepted Answer

On coated

Question 2

The cytoplasmic domain of ligand-bound LDL receptor binds to _______ proteins, which in turn associate with the _______ coat.

Accepted Answer

The answer of The cytoplasmic domain of ligand-bound LDL receptor...

Question 3

Which of the following will not solubilize a typical peripheral membrane protein?

Accepted Answer

A)  Detergent 
B)  Extreme pH 
C)  High salt concentration 
D)  Mildly hypertonic saline 
A)  Detergent 
B)  Extreme pH 
C)  High salt concentration 
D)  Mildly hypertonic saline

Question 4

Mammalian erythrocytes (red blood cells) are particularly useful for studies of the plasma membrane because

Accepted Answer

A)  they have few peripheral proteins. 
B)  they have only one membrane, the plasma membrane. 
C)  their plasma membrane is not associated with a cytoskeleton. 
D)  their plasma membrane contains no cholesterol. 
A)  they have few peripheral proteins. 
B)  they have only one membrane, the plasma membrane. 
C)  their plasma membrane is not associated with a cytoskeleton. 
D)  their plasma membrane contains no cholesterol.

Question 5

During facilitated diffusion of glucose, the glucose transporter changes its _______.

Accepted Answer

The answer of During facilitated diffusion of glucose, the glucose...

Question 6

The restriction of membrane protein movement between surfaces of intestinal epithelia is primarily due to the presence of _______ junctions between the epithelial cells.

Accepted Answer

The answer of The restriction of membrane protein movement between...

Question 7

Which statement about ion channels is true?

Accepted Answer

A)  They are opened either by the binding of ligands or by changes in electric potential across the membrane. 
B)  They require ATP. 
C)  They are open most of the time. 
D)  The rate of transport is slow compared to the rate of transport via carrier proteins. 
A)  They are opened either by the binding of ligands or by changes in electric potential across the membrane. 
B)  They require ATP. 
C)  They are open most of the time. 
D)  The rate of transport is slow compared to the rate of transport via carrier proteins.

Question 8

The Nernst equation allows one to calculate the

Accepted Answer

A)  resting membrane potential. 
B)  equilibrium potential for each ion. 
C)  membrane potential when all channels are closed. 
D)  membrane potential when all channels are open. 
A)  resting membrane potential. 
B)  equilibrium potential for each ion. 
C)  membrane potential when all channels are closed. 
D)  membrane potential when all channels are open.

Question 9

Which statement about the relative concentrations of Na+ and K+ inside and outside of a typical mammalian cell is true?

Accepted Answer

A)  The concentration of Na+ and K+ outside the cell is about 30 times higher than inside the cell. 
B)  The concentration of Na+ outside the cell is about 30 times higher than inside the cell, and the concentration of K+ inside the cell is 10 to 30 times higher than outside the cell. 
C)  The concentration is the same for both ions, but there is a Cl- ion concentration gradient across the plasma membrane. 
D)  The concentration of Na+ inside the cell is 30 times higher than outside the cell, and the concentration of K+ outside the cell is 10 times higher than inside the cell. 
A)  The concentration of Na+ and K+ outside the cell is about 30 times higher than inside the cell. 
B)  The concentration of Na+ outside the cell is about 30 times higher than inside the cell, and the concentration of K+ inside the cell is 10 to 30 times higher than outside the cell. 
C)  The concentration is the same for both ions, but there is a Cl- ion concentration gradient across the plasma membrane. 
D)  The concentration of Na+ inside the cell is 30 times higher than outside the cell, and the concentration of K+ outside the cell is 10 times higher than inside the cell.

Question 10

What is the primary reason that mammalian red blood cells are used in the study of the plasma membrane?

Accepted Answer

A)  There are a lot of them and they are easily obtained. 
B)  They contain larger plasma membranes than any other cell type. 
C)  They are of particular interest because they are made up of a lipid monolayer. 
D)  They lack nuclei and membrane-bounded organelles. 
A)  There are a lot of them and they are easily obtained. 
B)  They contain larger plasma membranes than any other cell type. 
C)  They are of particular interest because they are made up of a lipid monolayer. 
D)  They lack nuclei and membrane-bounded organelles.

Question 11

Which statement about ABC transporters is false?

Accepted Answer

A)  Each family member has an ATP-binding cassette. 
B)  Each member of the family is a Cl- channel. 
C)  They are the largest family of membrane transporters in humans. 
D)  Each member of the family has shared domain structure features. 
A)  Each family member has an ATP-binding cassette. 
B)  Each member of the family is a Cl- channel. 
C)  They are the largest family of membrane transporters in humans. 
D)  Each member of the family has shared domain structure features.

Question 12

In a typical mammalian cell, the concentration of _______ is higher on the inside, and the concentration of _______ is higher on the outside.

Accepted Answer

A)  Na+ and Cl-; K+ 
B)  Na+; K+ and Cl- 
C)  K+; Na+ and Cl- 
D)  K+ and Cl-; Na+ 
A)  Na+ and Cl-; K+ 
B)  Na+; K+ and Cl- 
C)  K+; Na+ and Cl- 
D)  K+ and Cl-; Na+

Question 13

Phagocytosis is the main function of what two types of human white blood cells?

Accepted Answer

A)  Macrophages and T lymphocytes 
B)  Platelets and neutrophils 
C)  Macrophages and neutrophils 
D)  Eosinophils and T lymphocytes 
A)  Macrophages and T lymphocytes 
B)  Platelets and neutrophils 
C)  Macrophages and neutrophils 
D)  Eosinophils and T lymphocytes

Question 14

The functioning of the Na+-Ca2+ transporter in the plasma membrane is an example of

Accepted Answer

A)  facilitated diffusion. 
B)  symport. 
C)  antiport. 
D)  endocytosis. 
A)  facilitated diffusion. 
B)  symport. 
C)  antiport. 
D)  endocytosis.

Question 15

Cystic fibrosis is a genetic disease in which thick mucus accumulates over several types of epithelial cells, eventually blocking the pulmonary airways. The molecular basis of this disease is the production of a defective

Accepted Answer

A)  mucin. 
B)  chloride channel. 
C)  Na+-K+ pump. 
D)  Na+-Ca2+ transporter. 
A)  mucin. 
B)  chloride channel. 
C)  Na+-K+ pump. 
D)  Na+-Ca2+ transporter.

Question 16

Above the temperature at which lipids are fluid, membrane proteins are able to move

Accepted Answer

A)  from inner to outer surfaces of a membrane. 
B)  laterally in the plane of a membrane. 
C)  from apical to basal surfaces of intestinal epithelial cells. 
D)  only if attached to microtubules or microfilaments. 
A)  from inner to outer surfaces of a membrane. 
B)  laterally in the plane of a membrane. 
C)  from apical to basal surfaces of intestinal epithelial cells. 
D)  only if attached to microtubules or microfilaments.

Question 17

Some plasma membrane proteins are immobilized by association with _______ proteins, other plasma membrane proteins, and the _______ matrix.

Accepted Answer

cytoskelet

Question 18

Calcium levels remain low in the cytosol

Accepted Answer

A)  only to ensure that calcium does not precipitate inside the cells. 
B)  thus transient calcium increases can be used as intracellular signals. 
C)  so that calcium does not accumulate in mitochondria. 
D)  to allow extracellular calcium to drive import of other ions. 
A)  only to ensure that calcium does not precipitate inside the cells. 
B)  thus transient calcium increases can be used as intracellular signals. 
C)  so that calcium does not accumulate in mitochondria. 
D)  to allow extracellular calcium to drive import of other ions.

Question 19

Which statement about the glucose transporter is false?

Accepted Answer

A)  It transports glucose across the plasma membrane via a mechanism called facilitated diffusion. 
B)  It has 12 $\alpha$-helical transmembrane segments. 
C)  A conformational change in the transporter is involved in the transport process. 
D)  Flow through it is unidirectional. 
A)  It transports glucose across the plasma membrane via a mechanism called facilitated diffusion. 
B)  It has 12 $\alpha$-helical transmembrane segments. 
C)  A conformational change in the transporter is involved in the transport process. 
D)  Flow through it is unidirectional.

Question 20

Coupled transport of glucose and Na+ into the intestinal epithelial cell is an example of

Accepted Answer

A)  facilitated diffusion. 
B)  symport. 
C)  antiport. 
D)  endocytosis. 
A)  facilitated diffusion. 
B)  symport. 
C)  antiport. 
D)  endocytosis.

Where is clathrin located in cells?

The cytoplasmic domain of ligand-bound LDL receptor binds to _ proteins, which in turn associate with the _ coat.

Which of the following will not solubilize a typical peripheral membrane protein?

Mammalian erythrocytes (red blood cells) are particularly useful for studies of the plasma membrane because

During facilitated diffusion of glucose, the glucose transporter changes its _______.

The restriction of membrane protein movement between surfaces of intestinal epithelia is primarily due to the presence of _______ junctions between the epithelial cells.

Which statement about ion channels is true?

The Nernst equation allows one to calculate the

Which statement about the relative concentrations of Na⁺ and K⁺ inside and outside of a typical mammalian cell is true?

What is the primary reason that mammalian red blood cells are used in the study of the plasma membrane?

Which statement about ABC transporters is false?

In a typical mammalian cell, the concentration of _ is higher on the inside, and the concentration of _ is higher on the outside.

Phagocytosis is the main function of what two types of human white blood cells?

The functioning of the Na⁺-Ca²⁺ transporter in the plasma membrane is an example of

Cystic fibrosis is a genetic disease in which thick mucus accumulates over several types of epithelial cells, eventually blocking the pulmonary airways. The molecular basis of this disease is the production of a defective

Above the temperature at which lipids are fluid, membrane proteins are able to move

Some plasma membrane proteins are immobilized by association with _ proteins, other plasma membrane proteins, and the _ matrix.

Calcium levels remain low in the cytosol

Which statement about the glucose transporter is false?

Coupled transport of glucose and Na⁺ into the intestinal epithelial cell is an example of

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 15: The Plasma Membrane

Where is clathrin located in cells?

The cytoplasmic domain of ligand-bound LDL receptor binds to _______ proteins, which in turn associate with the _______ coat.

Which of the following will not solubilize a typical peripheral membrane protein?

Mammalian erythrocytes (red blood cells) are particularly useful for studies of the plasma membrane because

During facilitated diffusion of glucose, the glucose transporter changes its _______.

The restriction of membrane protein movement between surfaces of intestinal epithelia is primarily due to the presence of _______ junctions between the epithelial cells.

Which statement about ion channels is true?

The Nernst equation allows one to calculate the

Which statement about the relative concentrations of Na+ and K+ inside and outside of a typical mammalian cell is true?

What is the primary reason that mammalian red blood cells are used in the study of the plasma membrane?

Which statement about ABC transporters is false?

In a typical mammalian cell, the concentration of _______ is higher on the inside, and the concentration of _______ is higher on the outside.

Phagocytosis is the main function of what two types of human white blood cells?

The functioning of the Na+-Ca2+ transporter in the plasma membrane is an example of

Cystic fibrosis is a genetic disease in which thick mucus accumulates over several types of epithelial cells, eventually blocking the pulmonary airways. The molecular basis of this disease is the production of a defective

Above the temperature at which lipids are fluid, membrane proteins are able to move

Some plasma membrane proteins are immobilized by association with _______ proteins, other plasma membrane proteins, and the _______ matrix.

Calcium levels remain low in the cytosol

Which statement about the glucose transporter is false?

Coupled transport of glucose and Na+ into the intestinal epithelial cell is an example of

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

The cytoplasmic domain of ligand-bound LDL receptor binds to _ proteins, which in turn associate with the _ coat.

Which statement about the relative concentrations of Na⁺ and K⁺ inside and outside of a typical mammalian cell is true?

In a typical mammalian cell, the concentration of _ is higher on the inside, and the concentration of _ is higher on the outside.

The functioning of the Na⁺-Ca²⁺ transporter in the plasma membrane is an example of

Some plasma membrane proteins are immobilized by association with _ proteins, other plasma membrane proteins, and the _ matrix.

Coupled transport of glucose and Na⁺ into the intestinal epithelial cell is an example of