Exam 15: The Plasma Membrane

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What is the role of tight junctions in the transport of glucose across the intestinal epithelium?

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Plasma membrane glycolipids are found

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In their acceptance speech for the Nobel Prize in 1985, Michael Brown and Joseph Goldstein said, "Cholesterol is a Janus-faced molecule. The very property that makes it useful in cell membranes, namely its absolute insolubility in water, also makes it lethal." Explain this remark.

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Cholesterol is taken up into most cells of the body by

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Some endocytic receptors are _______ from endosomes, while others are _______ in lysosomes.

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How is rapid transport of water across the plasma membrane achieved?

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The Na+ and K+ channels involved in the propagation of an action potential are _______-gated.

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Active transport can be driven by _______ hydrolysis or by _______ gradients.

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The two erythrocyte proteins glycophorin and band 3 are examples of

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The potentially oncogenic signal-transmitting proteins Src and Ras are attached to the inner surface of the plasma membrane by covalent links to _______.

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The endocytic trafficking pathway of ligands and receptors in eukaryotic cells is often controlled by sequential differences in _______ between early endosomes, late endosomes, and lysosomes.

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The plasma membrane's barrier to passive diffusion is primarily a function of the membrane's

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Gorter and Grendel's classic experiment allowed them to observe that the erythrocyte plasma membrane contains _______ the surface area of the erythrocytes.

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The K+-glucose transporter is an example of a symport that actively transports glucose into cells.

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What is the mechanism by which cells take up specific macromolecules?

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A major feature included in the updated fluid mosaic model is the

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The membrane-spanning portion of a single-pass transmembrane protein is usually a secondary structure called a(n) _______.

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Facilitated diffusion differs from passive diffusion in that facilitated diffusion is

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Caveolae are rich in cholesterol and other constituents of lipid rafts.

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Clusters of _______ in membrane proteins such as band 3 of the erythrocyte can define hydrophilic segments through which ions (for example, bicarbonate and chloride) can be transported.

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