Question 1

Which products would result from caspase cleavage of a protein with the amino acid sequence AVEELCSTWYYDLLCHMRTL?

Accepted Answer

A)  AVEELCS + TWYYDLLCHMRTL 
B)  AVEELCSTWYYD + LLCHMRTL 
C)  AVEELCSTWYYDLLCH + MRTL 
D)  AVEELC + STWYYDLLC + HMRTL 
A)  AVEELCS + TWYYDLLCHMRTL 
B)  AVEELCSTWYYD + LLCHMRTL 
C)  AVEELCSTWYYDLLCH + MRTL 
D)  AVEELC + STWYYDLLC + HMRTL

Question 2

In addition to cytochrome c, other proapoptotic factors are released from _______.

Accepted Answer

The answer of In addition to cytochrome c, other proapoptotic...

Question 3

Viral genomes are generally quite small, usually encoding only a small number of genes. Some identified viruses encode inhibitors of apoptosis (IAPs). With such a limited genome, why is it advantageous for a virus to have an IAP as part of its molecular machinery?

Accepted Answer

Once inside the host cell, viruses rely

Question 4

TNF and related cytokines can directly induce apoptosis. Which statement about TNF-mediated induction of apoptosis is true?

Accepted Answer

A)  TNF binds a trimeric receptor complex on the surface of the cell membrane. 
B)  Upon receptor binding, caspase-8 is activated through an adaptor protein. 
C)  Caspase-8 activates Bid, which in turn activates Bax and Bak and then feeds into the mitochondrial pathway. 
D)  All of the above statements are true. 
A)  TNF binds a trimeric receptor complex on the surface of the cell membrane. 
B)  Upon receptor binding, caspase-8 is activated through an adaptor protein. 
C)  Caspase-8 activates Bid, which in turn activates Bax and Bak and then feeds into the mitochondrial pathway. 
D)  All of the above statements are true.

Question 5

Which of the following is not a key property of stem cells in tissues?

Accepted Answer

A)  Dividing to produce one daughter cell that remains a stem cell 
B)  Dividing to produce one cell that then differentiates 
C)  Exhibiting self-renewal 
D)  Dividing within each tissue to maintain a set number of cells 
A)  Dividing to produce one daughter cell that remains a stem cell 
B)  Dividing to produce one cell that then differentiates 
C)  Exhibiting self-renewal 
D)  Dividing within each tissue to maintain a set number of cells

Question 6

VEGF is secreted by

Accepted Answer

A)  cells deprived of oxygen. 
B)  injured endothelial cells. 
C)  injured smooth muscle cells. 
D)  platelets. 
A)  cells deprived of oxygen. 
B)  injured endothelial cells. 
C)  injured smooth muscle cells. 
D)  platelets.

Question 7

Hematopoietic stem cells can give rise to

Accepted Answer

A)  erythrocytes. 
B)  erythrocytes and lymphocytes. 
C)  all blood cells and macrophages. 
D)  all blood cells, macrophages, and skin cells. 
A)  erythrocytes. 
B)  erythrocytes and lymphocytes. 
C)  all blood cells and macrophages. 
D)  all blood cells, macrophages, and skin cells.

Question 8

Many stimuli that trigger cell death release the molecule _______ from the intermembrane space of mitochondria so they can bind to Apaf-1.

Accepted Answer

A)  cytochrome c 
B)  citric acid 
C)  ubiquinone 
D)  ATP synthase 
A)  cytochrome c 
B)  citric acid 
C)  ubiquinone 
D)  ATP synthase

Question 9

Humans possess about _______ different cell types.

Accepted Answer

A)  100 
B)  200 
C)  500 
D)  1,000 
A)  100 
B)  200 
C)  500 
D)  1,000

Question 10

Describe some of the differences between adult-derived stem cells and embryonic stem cells.

Accepted Answer

The most obvious difference is the sourc

Question 11

Some differentiated cells retain the ability to proliferate as needed to repair damaged tissue throughout the life of the organism. Which of the following cell types do not retain this unique ability?

Accepted Answer

A)  Fibroblasts 
B)  Neurons 
C)  Endothelial cells 
D)  Epithelial cells 
A)  Fibroblasts 
B)  Neurons 
C)  Endothelial cells 
D)  Epithelial cells

Question 12

Which of the following diseases would not be an ideal target for therapeutic cloning?

Accepted Answer

A)  HIV 
B)  Parkinson's disease 
C)  Spinal cord injury 
D)  Diabetes 
A)  HIV 
B)  Parkinson's disease 
C)  Spinal cord injury 
D)  Diabetes

Question 13

Ced-9 functions directly to

Accepted Answer

A)  inhibit Ced-3. 
B)  inhibit Ced-4. 
C)  stimulate Ced-3. 
D)  stimulate Ced-4. 
A)  inhibit Ced-3. 
B)  inhibit Ced-4. 
C)  stimulate Ced-3. 
D)  stimulate Ced-4.

Question 14

Which of the following are the three core transcription factors that can reprogram adult somatic cells into induced pluripotent cells?

Accepted Answer

A)  Sox2, Oct4, and Nanog 
B)  Sox2, Oct4, and Hedgehog 
C)  Oct4, c-Myc, and Klf4 
D)  Sox2, c-Myc, and Nanog 
A)  Sox2, Oct4, and Nanog 
B)  Sox2, Oct4, and Hedgehog 
C)  Oct4, c-Myc, and Klf4 
D)  Sox2, c-Myc, and Nanog

Question 15

Which of the following is not considered a viable source of stem cells?

Accepted Answer

A)  Umbilical cord blood 
B)  Bone marrow 
C)  An embryo 
D)  Tumor cell 
A)  Umbilical cord blood 
B)  Bone marrow 
C)  An embryo 
D)  Tumor cell

Question 16

Name two types of cells, other than cancer cells, that are killed by tumor necrosis factor (TNF).

Accepted Answer

Virus-infected cells and exces

Question 17

What is the difference between reproductive and therapeutic cloning?

Accepted Answer

Therapeutic cloning is the production of

Question 18

When stem cells of the intestinal epithelium and epidermis divide, they give rise to two different cells: one stem cell and one _______ cell.

Accepted Answer

A)  goblet 
B)  crypt 
C)  G0 
D)  transit-amplifying 
A)  goblet 
B)  crypt 
C)  G0 
D)  transit-amplifying

Question 19

If the gene _______ is mutated in C. elegans so that it does not function, no cells will die during development.

Accepted Answer

The answer of If the gene _______ is mutated in...

Question 20

Provide three examples of normal human cells that, in their fully differentiated form, can no longer proliferate but can be replaced by means of stem cell proliferation and differentiation.

Accepted Answer

Any three of the following: bl

Which products would result from caspase cleavage of a protein with the amino acid sequence AVEELCSTWYYDLLCHMRTL?

In addition to cytochrome c, other proapoptotic factors are released from _______.

Viral genomes are generally quite small, usually encoding only a small number of genes. Some identified viruses encode inhibitors of apoptosis (IAPs). With such a limited genome, why is it advantageous for a virus to have an IAP as part of its molecular machinery?

TNF and related cytokines can directly induce apoptosis. Which statement about TNF-mediated induction of apoptosis is true?

Which of the following is not a key property of stem cells in tissues?

VEGF is secreted by

Hematopoietic stem cells can give rise to

Many stimuli that trigger cell death release the molecule _______ from the intermembrane space of mitochondria so they can bind to Apaf-1.

Humans possess about _______ different cell types.

Describe some of the differences between adult-derived stem cells and embryonic stem cells.

Some differentiated cells retain the ability to proliferate as needed to repair damaged tissue throughout the life of the organism. Which of the following cell types do not retain this unique ability?

Which of the following diseases would not be an ideal target for therapeutic cloning?

Ced-9 functions directly to

Which of the following are the three core transcription factors that can reprogram adult somatic cells into induced pluripotent cells?

Which of the following is not considered a viable source of stem cells?

Name two types of cells, other than cancer cells, that are killed by tumor necrosis factor (TNF).

What is the difference between reproductive and therapeutic cloning?

When stem cells of the intestinal epithelium and epidermis divide, they give rise to two different cells: one stem cell and one _______ cell.

If the gene _______ is mutated in C. elegans so that it does not function, no cells will die during development.

Provide three examples of normal human cells that, in their fully differentiated form, can no longer proliferate but can be replaced by means of stem cell proliferation and differentiation.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cancer

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Exam 19: Cell Death and Cell Renewal

Which products would result from caspase cleavage of a protein with the amino acid sequence AVEELCSTWYYDLLCHMRTL?

In addition to cytochrome c, other proapoptotic factors are released from _______.

Viral genomes are generally quite small, usually encoding only a small number of genes. Some identified viruses encode inhibitors of apoptosis (IAPs). With such a limited genome, why is it advantageous for a virus to have an IAP as part of its molecular machinery?

TNF and related cytokines can directly induce apoptosis. Which statement about TNF-mediated induction of apoptosis is true?

Which of the following is not a key property of stem cells in tissues?

VEGF is secreted by

Hematopoietic stem cells can give rise to

Many stimuli that trigger cell death release the molecule _______ from the intermembrane space of mitochondria so they can bind to Apaf-1.

Humans possess about _______ different cell types.

Describe some of the differences between adult-derived stem cells and embryonic stem cells.

Some differentiated cells retain the ability to proliferate as needed to repair damaged tissue throughout the life of the organism. Which of the following cell types do not retain this unique ability?

Which of the following diseases would not be an ideal target for therapeutic cloning?

Ced-9 functions directly to

Which of the following are the three core transcription factors that can reprogram adult somatic cells into induced pluripotent cells?

Which of the following is not considered a viable source of stem cells?

Name two types of cells, other than cancer cells, that are killed by tumor necrosis factor (TNF).

What is the difference between reproductive and therapeutic cloning?

When stem cells of the intestinal epithelium and epidermis divide, they give rise to two different cells: one stem cell and one _______ cell.

If the gene _______ is mutated in C. elegans so that it does not function, no cells will die during development.

Provide three examples of normal human cells that, in their fully differentiated form, can no longer proliferate but can be replaced by means of stem cell proliferation and differentiation.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cancer

Filters