Question 1

What is the function of the kinins released when mast cells degranulate?

Accepted Answer

A)  activation of the complement system 
B)  increased vascular permeability 
C)  smooth muscle contraction 
D)  increased production of tears and saliva 
E)  chemotactic factors 
A)  activation of the complement system 
B)  increased vascular permeability 
C)  smooth muscle contraction 
D)  increased production of tears and saliva 
E)  chemotactic factors

Question 2

Which of the following statements concerning allografts is TRUE?

Accepted Answer

A)  They are the best type of transplants because they are not associated with rejection. 
B)  They induce strong type IV hypersensitivity reactions and must be treated with immunosuppressive drugs. 
C)  They always require complete destruction of the recipient's bone marrow cells. 
D)  They are impossible to perform because the antigens between donor and recipient are so different. 
E)  They are the rarest type of transplants. 
A)  They are the best type of transplants because they are not associated with rejection. 
B)  They induce strong type IV hypersensitivity reactions and must be treated with immunosuppressive drugs. 
C)  They always require complete destruction of the recipient's bone marrow cells. 
D)  They are impossible to perform because the antigens between donor and recipient are so different. 
E)  They are the rarest type of transplants.

Question 3

Hypotheses explaining the development of autoimmune disease include

Accepted Answer

A)  molecular mimicry. 
B)  genetic factors. 
C)  overuse of vaccines. 
D)  molecular mimicry and vaccines. 
E)  molecular mimicry and genetic factors. 
A)  molecular mimicry. 
B)  genetic factors. 
C)  overuse of vaccines. 
D)  molecular mimicry and vaccines. 
E)  molecular mimicry and genetic factors.

Question 4

Infection with certain viruses may lead to the development of type I diabetes.

Accepted Answer

A) True 
 B)False

Question 5

If circulating immune complexes are deposited in the glomeruli,the ensuing type III hypersensitivity reaction can result in

Accepted Answer

A)  allergic contact dermatitis. 
B)  pneumonitis. 
C)  kidney damage. 
D)  multiple sclerosis. 
E)  rheumatoid arthritis. 
A)  allergic contact dermatitis. 
B)  pneumonitis. 
C)  kidney damage. 
D)  multiple sclerosis. 
E)  rheumatoid arthritis.

Question 6

All autoimmune diseases have a genetic cause.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following is the mechanism of action of cyclosporine?

Accepted Answer

A)  It blocks the complement cascade. 
B)  It blocks the activity of activated Th1 T cells. 
C)  It directly blocks CTL activity. 
D)  It interferes with activation of Th2 T cells. 
E)  It is an anti-inflammatory interfering with leukotriene function. 
A)  It blocks the complement cascade. 
B)  It blocks the activity of activated Th1 T cells. 
C)  It directly blocks CTL activity. 
D)  It interferes with activation of Th2 T cells. 
E)  It is an anti-inflammatory interfering with leukotriene function.

Question 8

Many of the signs and symptoms of inflammation,including redness and itching,are due to the release of (histamines/leukotrienes/proteases)by degranulation of mast cells.

Accepted Answer

The answer of Many of the signs and symptoms of...

Question 9

If an Rh-positive woman marries an Rh-negative man,their children are at risk for hemolytic disease of the newborn.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following statements concerning rheumatoid arthritis (RA) is TRUE?

Accepted Answer

A)  It occurs in humans and animals. 
B)  The symptoms are due to damage caused by cytotoxic T cells. 
C)  There is no genetic influence on the likelihood of developing RA. 
D)  Accumulations of antibody complexes lead to inflammation in and destruction of the joints. 
A)  It occurs in humans and animals. 
B)  The symptoms are due to damage caused by cytotoxic T cells. 
C)  There is no genetic influence on the likelihood of developing RA. 
D)  Accumulations of antibody complexes lead to inflammation in and destruction of the joints.

Question 11

Which of the following bind the constant region of IgE?

Accepted Answer

A)  eosinophils 
B)  mast cells 
C)  monocytes 
D)  both mast cells and monocytes 
E)  both eosinophils and mast cells 
A)  eosinophils 
B)  mast cells 
C)  monocytes 
D)  both mast cells and monocytes 
E)  both eosinophils and mast cells

Question 12

Systemic lupus erythematosus (SLE)is a disease resulting from accumulation of immune complexes in various organs and tissues.

Accepted Answer

A) True 
 B)False

Question 13

If a T cell is exposed to a "hidden" antigen,what kind of immune reaction will result?

Accepted Answer

A)  an autoimmune disease 
B)  a delayed hypersensitivity reaction 
C)  a cytotoxic hypersensitivity reaction 
D)  allergic contact dermatitis 
E)  an allergy 
A)  an autoimmune disease 
B)  a delayed hypersensitivity reaction 
C)  a cytotoxic hypersensitivity reaction 
D)  allergic contact dermatitis 
E)  an allergy

Question 14

Which of the following is both a hypersensitivity disorder and an autoimmune disorder?

Accepted Answer

A)  anaphylaxis 
B)  glomerulonephritis 
C)  graft rejection 
D)  hemolytic disease of the newborn 
E)  rheumatoid arthritis 
A)  anaphylaxis 
B)  glomerulonephritis 
C)  graft rejection 
D)  hemolytic disease of the newborn 
E)  rheumatoid arthritis

Question 15

Multiple sclerosis is

Accepted Answer

A)  a type IV hypersensitivity disease in which cytotoxic T cells attack the myelin sheath of neurons. 
B)  a genetic birth defect of the nervous system. 
C)  a type II hypersensitivity to the myelin of neurons. 
D)  the formation of antibodies against transplanted tissue. 
E)  a neurological disease due to the accumulation of immune complexes in nerves. 
A)  a type IV hypersensitivity disease in which cytotoxic T cells attack the myelin sheath of neurons. 
B)  a genetic birth defect of the nervous system. 
C)  a type II hypersensitivity to the myelin of neurons. 
D)  the formation of antibodies against transplanted tissue. 
E)  a neurological disease due to the accumulation of immune complexes in nerves.

Question 16

Primary immunodeficiency diseases

Accepted Answer

A)  develop later in life. 
B)  are detectable close to birth. 
C)  may be caused by malnutrition. 
D)  are never associated with genetic defects. 
E)  are sometimes caused by severe stress. 
A)  develop later in life. 
B)  are detectable close to birth. 
C)  may be caused by malnutrition. 
D)  are never associated with genetic defects. 
E)  are sometimes caused by severe stress.

Question 17

Which of the following would test positive for the tuberculin response?

Accepted Answer

A)  someone who has previously had tuberculosis 
B)  someone who has been immunized with the tuberculosis vaccine 
C)  someone who has previously been injected subcutaneously with tuberculin 
D)  someone who has been immunized with the tuberculosis vaccine or has previously had tuberculosis 
E)  someone who has been immunized with the tuberculosis vaccine or previously been injected subcutaneously with tuberculin 
A)  someone who has previously had tuberculosis 
B)  someone who has been immunized with the tuberculosis vaccine 
C)  someone who has previously been injected subcutaneously with tuberculin 
D)  someone who has been immunized with the tuberculosis vaccine or has previously had tuberculosis 
E)  someone who has been immunized with the tuberculosis vaccine or previously been injected subcutaneously with tuberculin

Question 18

The mechanism of action of RhoGAM is to (activate/neutralize/prevent)an anti-Rh immune response.

Accepted Answer

The answer of The mechanism of action of RhoGAM is...

Question 19

Which hypersensitivity disorder is the result of cell-mediated response?

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  both type I and II 
A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  both type I and II

Question 20

Graves' disease is an autoimmune disease that affects the (lymph/thyroid/adrenal)gland.

Accepted Answer

The answer of Graves' disease is an autoimmune disease that...

Exam 18: Immune Disorders

What is the function of the kinins released when mast cells degranulate?

Which of the following statements concerning allografts is TRUE?

Hypotheses explaining the development of autoimmune disease include

Infection with certain viruses may lead to the development of type I diabetes.

If circulating immune complexes are deposited in the glomeruli,the ensuing type III hypersensitivity reaction can result in

All autoimmune diseases have a genetic cause.

Which of the following is the mechanism of action of cyclosporine?

Many of the signs and symptoms of inflammation,including redness and itching,are due to the release of (histamines/leukotrienes/proteases)by degranulation of mast cells.

If an Rh-positive woman marries an Rh-negative man,their children are at risk for hemolytic disease of the newborn.

Which of the following statements concerning rheumatoid arthritis (RA) is TRUE?

Which of the following bind the constant region of IgE?

Systemic lupus erythematosus (SLE)is a disease resulting from accumulation of immune complexes in various organs and tissues.

If a T cell is exposed to a "hidden" antigen,what kind of immune reaction will result?

Which of the following is both a hypersensitivity disorder and an autoimmune disorder?

Multiple sclerosis is

Primary immunodeficiency diseases

Which of the following would test positive for the tuberculin response?

The mechanism of action of RhoGAM is to (activate/neutralize/prevent)an anti-Rh immune response.

Which hypersensitivity disorder is the result of cell-mediated response?

Graves' disease is an autoimmune disease that affects the (lymph/thyroid/adrenal)gland.

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