Exam 12: Body Defenses

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Endogenous pyrogen (EP), leukocyte endogenous mediator (LEM), and interleukin 1 (IL-1) are all believed to be identical or closely related chemical mediators.

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What type of immune defense cell is selectively invaded by AIDS virus?

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Complete each of the following statments. A mass of transformed cells that is slow-growing, stays put, and does not infiltrate surrounding tissue is known as a(n) ____________________ tumor, whereas rapidly growing, invasive masses are called ____________________ tumors or ____________________. The spreading of mutant cells that have broken away from the parent tumor to other body sites is called ____________________.

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IgM immunoglobulin

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Hives result from an allergy-induced histamine release.

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Complete each of the following statments. Most of the progeny of an activated B-cell clone differentiate into ____________________, which produce antibodies, and ____________________, which remain dormant and expand the specific clone.

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Match the defense molecule with the correct characteristic.
interferon
Form(s) a membrane-attack complex
complement
Produced by plasma cells
lactoferrin
Enhance(s) phagocytosis by linking the foreign cell to a phagocytic cell
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interferon
Form(s) a membrane-attack complex
complement
Produced by plasma cells
lactoferrin
Enhance(s) phagocytosis by linking the foreign cell to a phagocytic cell
pyrogens
Potent anti-inflammatory drug(s)
opsonins
Induce(s) the development of fever
histamine
Tightly binds with iron, making it unavailable for use by invading bacteria
glucocorticoids
Released from mast cells and causes localized vasodilation in a region of tissue damage
antibodies
Stimulates production of viral-blocking enzymes
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T cells typically bind with MHC self-antigens only when they are in association with foreign antigen.

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Complete each of the following statments. A pyrogen induces the development of ____________________.

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Use this figure to answer the corresponding questions. Number 1 is a(n) ____________________ cell, and number 6 is a(n) ____________________ cell. Use this figure to answer the corresponding questions. Number 1 is a(n) ____________________ cell, and number 6 is a(n) ____________________ cell.

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Define the complement system and describe the two ways in which it can be activated, then describe four ways that activated complement contributes to the body's defense.

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Lactoferrin is a protein that binds with iron.

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The epidermis

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Passive immunity is accomplished by transfer of ____ antibodies.

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Nonspecific immune responses

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Complete each of the following statments. ____________________ cells do not participate in an immune reaction but remain dormant to expand a specific clone.

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Interferon is released only from phagocytic cells that have been invaded by viruses.

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Neutrophils are the first phagocytes to leave the blood and arrive at a site of bacterial invasion or tissue damage.

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Cytotoxic T cells are one of several kinds of regulatory T cells.

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Viral-blocking enzymes are

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