Question 1

What would be the major product of the following reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  A mixture of I and II 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  A mixture of I and II

Question 2

Outline the steps involved in the synthesis of p-methoxybenzoic acid from phenol.

Accepted Answer

i)NaOH ;
ii)CH3I;
ii

Question 3

Outline the steps involved in the synthesis of 3-nitrophenol from 1,3-dinitrobenzene

Accepted Answer

i)NH₃,H₂S,Et

Question 4

Draw the structure of the final product obtained when 1-chloro-2,4-dinitrobenzene is heated with aqueous NaHCO3 at 100oC,followed by neutralization with H3O+ .

Accepted Answer

Question 5

Eugenol,isolated from cloves,has the following structure:   Which of the following signals is NOT expected to be observed in its NMR spectrum?

Accepted Answer

A)  Singlet at ~4 ppm (3H) 
B)  Doublet at ~2.5 ppm (2H) 
C)  Singlet at ~ 7 ppm (1H) 
D)  Singlet at ~ 6 ppm (1H) 
E)  All of the above types of signals are expected to be observed 
A)  Singlet at ~4 ppm (3H) 
B)  Doublet at ~2.5 ppm (2H) 
C)  Singlet at ~ 7 ppm (1H) 
D)  Singlet at ~ 6 ppm (1H) 
E)  All of the above types of signals are expected to be observed

Question 6

What are the products of the reaction of phenol with propanoic anhydride in the presence of base?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 7

Draw the structure of the product likely to be obtained from the reaction between acetoacetic ester,bromobenzene and 2 molar equivalents of sodium amide (in liquid ammonia)? Briefly explain your rationale.

Accepted Answer

This is likely to be a benzyne mediated

Question 8

Draw the structure corresponding to the following IUPAC name:
4-benzyl-3,5-diiodophenol

Accepted Answer

The answer of Draw the structure corresponding to the following...

Question 9

Draw the structure of the product obtained when benzoquinone reacts with 2 molar equivalents of 1,3-butadiene via a Diels Alder reaction.

Accepted Answer

The answer of Draw the structure of the product obtained...

Question 10

Discuss the following reaction
(a)Williamson's synthesis (b)Kolbe's reaction

Accepted Answer

(a)Williamson's synthesis @#IMG-DLM& (b)Kolbe's re

Question 11

The commonly used name for hydroxybenzene is __________.

Accepted Answer

The answer of The commonly used name for hydroxybenzene is...

Question 12

Which of these reactions does not produce phenol? I think this question is ok

Accepted Answer

A) 
  
B) 
  
C) 
  
D) 
  
E) 
  
A) 
  
B) 
  
C) 
  
D) 
  
E)

Question 13

Arrange the following in increasing order of acidity.

Accepted Answer

The answer of Arrange the following in increasing order of...

Question 14

In terms of reactivity towards nucleophiles,bromobenzene is most similar to which of these?

Accepted Answer

A)  Allyl bromide 
B)  Vinyl bromide 
C)  tert-Butyl bromide 
D)  Propyl bromide 
E)  Methyl bromide 
A)  Allyl bromide 
B)  Vinyl bromide 
C)  tert-Butyl bromide 
D)  Propyl bromide 
E)  Methyl bromide

Question 15

In general,there are two types of nucleophilic aromatic substitution mechanisms.These are: ______________.

Accepted Answer

addition-elimination

Question 16

Nucleophilic aromatic substitution reactions (SNAr)require three components: a good leaving group on the aromatic ring,a strong nucleophile,and ________________.

Accepted Answer

an electron-withdraw

Question 17

Write structural formulas for important products.
   1.
   2.
   3.
   4.
   5.
6.

Accepted Answer

The answer of Write structural formulas for important products.
 ...

Question 18

Most of the worldwide industrial preparation of phenol is now based on the ___________.

Accepted Answer

cumene hyd

Question 19

Nucleophilic aromatic substitution reactions (SNAr)take place via a delocalized carbanion intermediate called a ______________.

Accepted Answer

Meisenheim

Question 20

What is the IUPAC name for

Accepted Answer

A)  p-Hydroxyphenol 
B)  p-Dihydroxybenzene 
C)  Resorcinol 
D)  1,4-dihydroxybenzene 
E)  4-methylphenol 
A)  p-Hydroxyphenol 
B)  p-Dihydroxybenzene 
C)  Resorcinol 
D)  1,4-dihydroxybenzene 
E)  4-methylphenol

Exam 21: Phenols and Aryl Halides: Nucleophilic Aromatic Substitution

What would be the major product of the following reaction?

Outline the steps involved in the synthesis of p-methoxybenzoic acid from phenol.

Outline the steps involved in the synthesis of 3-nitrophenol from 1,3-dinitrobenzene

Draw the structure of the final product obtained when 1-chloro-2,4-dinitrobenzene is heated with aqueous NaHCO3 at 100oC,followed by neutralization with H3O+ .

Eugenol,isolated from cloves,has the following structure: Which of the following signals is NOT expected to be observed in its NMR spectrum?

What are the products of the reaction of phenol with propanoic anhydride in the presence of base?

Draw the structure of the product likely to be obtained from the reaction between acetoacetic ester,bromobenzene and 2 molar equivalents of sodium amide (in liquid ammonia)? Briefly explain your rationale.

Draw the structure corresponding to the following IUPAC name: 4-benzyl-3,5-diiodophenol

Draw the structure of the product obtained when benzoquinone reacts with 2 molar equivalents of 1,3-butadiene via a Diels Alder reaction.

Discuss the following reaction (a)Williamson's synthesis (b)Kolbe's reaction

The commonly used name for hydroxybenzene is __________.

Which of these reactions does not produce phenol? I think this question is ok

Arrange the following in increasing order of acidity.

In terms of reactivity towards nucleophiles,bromobenzene is most similar to which of these?

In general,there are two types of nucleophilic aromatic substitution mechanisms.These are: ______________.

Nucleophilic aromatic substitution reactions (SNAr)require three components: a good leaving group on the aromatic ring,a strong nucleophile,and ________________.

Write structural formulas for important products. 1. 2. 3. 4. 5. 6.

Most of the worldwide industrial preparation of phenol is now based on the ___________.

Nucleophilic aromatic substitution reactions (SNAr)take place via a delocalized carbanion intermediate called a ______________.

What is the IUPAC name for

Carbon Compounds and Chemical Bonds

Representative Carbon Compounds: Functional Groups, Intermolecular Forces, and Infrared Ir Spectroscopy

An Introduction to Organic Reactions: Acids and Bases

Alkanes: Nomenclature, Conformational Analysis, and an Introduction to Synthesis

Stereochemistry: Chiral Molecules

Ionic Reactions - Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

Alkenes and Alkynes I: Properties and Synthesis, Elimination Reactions of Alkyl Halides

Alkenes and Alkynes Ii: Addition Reactions

Nuclear Magnetic Resonance and Mass Spectrometry: Tools for Structure Determination

Radical Reactions

Alcohols and Ethers

Alcohols From Carbonyl Compounds Oxidation-Reduction and Organometallic Compounds

Conjugated Unsaturated Systems

Aromatic Compounds

Reactions of Aromatic Compounds

Aldehydes and Ketones I Nucleophilic Addition to the Carbonyl Group

Aldehydes and Ketones Ii Aldol Reactions

Carboxylic Acids and Their Derivatives Nucleophilic Addition - Elimination at the Acyl Carbon

Synthesis and Reactions of Beta-Dicarbonyl Compounds: More Chemistry of Enolate Ions

Amines

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids and Protein Synthesis

Filters

Draw the structure of the final product obtained when 1-chloro-2,4-dinitrobenzene is heated with aqueous NaHCO₃ at 100^oC,followed by neutralization with H₃O⁺ .

Nucleophilic aromatic substitution reactions (S_NAr)require three components: a good leaving group on the aromatic ring,a strong nucleophile,and ________________.

Nucleophilic aromatic substitution reactions (S_NAr)take place via a delocalized carbanion intermediate called a ______________.