Exam 21: Phenols and Aryl Halides: Nucleophilic Aromatic Substitution

The formation of equal amounts of m-toluidine (m-aminotoluene)and p-toluidine in the reaction of p-bromotoluene with sodium amide in liquid ammonia at -33 $\degree$ C suggests this species as the reaction intermediate:

What is the IUPAC name for

Which of the following reactions would yield p-tert-butylphenol?

Nitration of phenol gives only ortho and para products.What is the reason for this?

Draw the structure of the product obtained when the following substance is heated strongly:

Which compound would be most acidic?

Methyl salicylate,commonly found in topical muscle relaxants,has the following structure: Which of the following signals is NOT expected to be observed in its NMR spectrum?

Write the IUPAC name of aspirin and its use.

A key step in the industrial synthesis of phenol from cumene is the oxidation of cumene to cumene hydroperoxide with oxygen.Outline the mechanistic steps that lead to this oxidation product.

The common name for 4-methylphenol is which of these?

Draw the structure of the final product obtained when 2-nitrophenol reacts with acetic anhydride in presence of base.

What product is likely to be obtained by the action of Ag⁺ or Fe⁺³ on the following substance?

Predict the product of this Cope rearrangement:

Which is the leaving group when the following substance reacts with sodium cyanide in DMSO solution?

Discuss the less boiling point of o-nitrophenol compared to p-nitrophenol.

What is the common name for

The carbon-halogen bonds in aryl and vinyl halides are both __________ and _____________ than the corresponding bonds in alkyl halides.

Benzyne is a very unstable intermediate,because _____________.

The common name for 3-methylphenol is which of these?

Indicate the correct product,if any,of the following reaction.