Exam 8: The Normochromic Anemias Caused by Hemoglobinopathies

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The hemolytic anemias are generally classified morphologically as:

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A 26-year-old day laborer with a long history of anemia has a several-month history of dyspnea, fever, and pulmonary pain.Additionally, he complains of tightness in the chest and upper abdominal region.His hematology values are as follows: WBC 15.9 109/L RBC 2.9 1012/L Hgb 9.5 g/dL Hct 30% MCV 103 fL MCH 31 pg MCHC 32% NRBC 15/100 WBC Platelets 275 109/L Reticulocytes 16.8% The hemoglobin electrophoresis results are as follows: Hgb A = 3% Hgb A2 = 2% Hgb S = 85% Hgb F = 10% The most likely diagnosis is:

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The lungs are particularly susceptible in individuals with sickle cell disease and may be involved in:

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