Question 1

Pegged or absent maxillary lateral incisors:

Accepted Answer

A) affect the secondary but not primary dentition. 
B) have a prevalence of 10% in the white population. 
C) are accompanied by congenitally lacking premolar teeth in 10% to 20% of the population. 
D) are generally an autosomal-recessive trait with variable expressivity. 
A) affect the secondary but not primary dentition. 
B) have a prevalence of 10% in the white population. 
C) are accompanied by congenitally lacking premolar teeth in 10% to 20% of the population. 
D) are generally an autosomal-recessive trait with variable expressivity.

Question 2

A mother who is a carrier of an X-linked recessive trait has a 50% risk of having a(n):

Accepted Answer

A) affected son or daughter. 
B) carrier son or daughter. 
C) affected son or a carrier daughter. 
D) carrier son or an affected daughter. 
A) affected son or daughter. 
B) carrier son or daughter. 
C) affected son or a carrier daughter. 
D) carrier son or an affected daughter.

Question 3

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

Accepted Answer

A) 10 
B) 25 
C) 50 
D) 90 
A) 10 
B) 25 
C) 50 
D) 90

Question 4

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

Accepted Answer

A) osteogenesis imperfecta 
B) mandibulofacial dysostosis 
C) cherubism 
D) cleidocranial dysplasia 
A) osteogenesis imperfecta 
B) mandibulofacial dysostosis 
C) cherubism 
D) cleidocranial dysplasia

Question 5

Each of the following statements about chromosomes is true except one. Which one is the exception?

Accepted Answer

A) Chromosomes are located in the nucleus of the cell. 
B) Hereditary units called genes are found on chromosomes. 
C) Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing. 
D) Chromosomes contain RNA, which directs the production of amino acids, polypeptides, and proteins by the cell. 
A) Chromosomes are located in the nucleus of the cell. 
B) Hereditary units called genes are found on chromosomes. 
C) Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing. 
D) Chromosomes contain RNA, which directs the production of amino acids, polypeptides, and proteins by the cell.

Question 6

Radicular dentin dysplasia is characterized by teeth with _____ crowns and _____ roots.

Accepted Answer

A) normal; normal 
B) normal; abnormal 
C) abnormal; normal 
D) abnormal; abnormal 
A) normal; normal 
B) normal; abnormal 
C) abnormal; normal 
D) abnormal; abnormal

Question 7

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

Accepted Answer

A) penetrance 
B) expressivity 
C) heterogeneity 
D) consanguinity 
A) penetrance 
B) expressivity 
C) heterogeneity 
D) consanguinity

Question 8

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.

-Cri du chat

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 9

The areas of bony radiolucency seen in cherubism:

Accepted Answer

A) resemble a central giant cell granuloma when seen under the microscope. 
B) occur in place of the teeth, and radiographs will reveal complete anodontia. 
C) will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D) will resolve, leaving the patient without any sign of facial deformity later in life. 
A) resemble a central giant cell granuloma when seen under the microscope. 
B) occur in place of the teeth, and radiographs will reveal complete anodontia. 
C) will increase in size as the patient matures, even until the seventh or eighth decade of life. 
D) will resolve, leaving the patient without any sign of facial deformity later in life.

Question 10

Murray-Puretic-Drescher syndrome is also known as:

Accepted Answer

A) cherubism. 
B) gingival fibromatosis with multiple hyaline fibromas. 
C) gingival fibromatosis with hypertrichosis, epilepsy, and mental retardation syndrome. 
D) Laband syndrome. 
A) cherubism. 
B) gingival fibromatosis with multiple hyaline fibromas. 
C) gingival fibromatosis with hypertrichosis, epilepsy, and mental retardation syndrome. 
D) Laband syndrome.

Question 11

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-The observable appearance of an individual

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 12

Which of the following statements about the hereditary opalescent form of dentinogenesis imperfecta is true?

Accepted Answer

A) It is associated with taurodontic teeth. 
B) Teeth have bulbous crowns with a color that varies from opalescent brown to brownish blue. 
C) Large pulp chambers and root canals are seen on radiographs. 
D) Roots are long and thick with periapical radiopacities. 
A) It is associated with taurodontic teeth. 
B) Teeth have bulbous crowns with a color that varies from opalescent brown to brownish blue. 
C) Large pulp chambers and root canals are seen on radiographs. 
D) Roots are long and thick with periapical radiopacities.

Question 13

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

Accepted Answer

A) hypoplastic 
B) hypocalcified 
C) hypomaturation 
D) hypoplastic-hypomaturation 
A) hypoplastic 
B) hypocalcified 
C) hypomaturation 
D) hypoplastic-hypomaturation

Question 14

__________ is an inherited disorder affecting the gingiva and periodontium, which is characterized by hyperkeratosis of the palms of the hands and soles of the feet.

Accepted Answer

A) Cyclic neutropenia 
B) Papillon-Lefèvre syndrome 
C) Gingival fibromatosis 
D) Laband syndrome 
A) Cyclic neutropenia 
B) Papillon-Lefèvre syndrome 
C) Gingival fibromatosis 
D) Laband syndrome

Question 15

Which of the following statements is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?

Accepted Answer

A) Aneuploidy is a complete second set of chromosomes, meaning a total of 46. 
B) Polyploidy is any number of chromosomes that do not represent an exact multiple of the total chromosome complement. 
C) Euploidy is a complete second set of chromosomes, meaning a total of 46. 
D) Aneuploidy may be represented by trisomy and monosomy. 
A) Aneuploidy is a complete second set of chromosomes, meaning a total of 46. 
B) Polyploidy is any number of chromosomes that do not represent an exact multiple of the total chromosome complement. 
C) Euploidy is a complete second set of chromosomes, meaning a total of 46. 
D) Aneuploidy may be represented by trisomy and monosomy.

Question 16

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

Accepted Answer

A) 0 to 0.5 
B) 1.5 to 2 
C) 4 to 6 
D) 8 to 9 
A) 0 to 0.5 
B) 1.5 to 2 
C) 4 to 6 
D) 8 to 9

Question 17

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-Nonsex chromosomes that are identical for men and women

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 18

Which of the following statements is true of oogenesis?

Accepted Answer

A) Oogenesis starts around the time of puberty. 
B) The second meiosis is completed at the beginning of ovulation. 
C) Nondisjunction is more prevalent in male spermatogenesis than in female oogenesis. 
D) The older the woman, the greater the chance of shedding a trisomic ovum. 
A) Oogenesis starts around the time of puberty. 
B) The second meiosis is completed at the beginning of ovulation. 
C) Nondisjunction is more prevalent in male spermatogenesis than in female oogenesis. 
D) The older the woman, the greater the chance of shedding a trisomic ovum.

Question 19

Hypophosphatasia is characterized by:

Accepted Answer

A) an increase in serum alkaline phosphatase levels. 
B) abnormal formation of enamel and dentin. 
C) exfoliation of teeth without evidence of periodontal or gingival disease. 
D) an autosomal-dominant inheritance pattern. 
A) an increase in serum alkaline phosphatase levels. 
B) abnormal formation of enamel and dentin. 
C) exfoliation of teeth without evidence of periodontal or gingival disease. 
D) an autosomal-dominant inheritance pattern.

Question 20

Telangiectasias of the oral mucosa for a patient with hereditary hemorrhagic telangiectasia will be especially prominent on the:

Accepted Answer

A) tip and anterior dorsum of the tongue. 
B) palate. 
C) gingiva. 
D) buccal mucosa. 
A) tip and anterior dorsum of the tongue. 
B) palate. 
C) gingiva. 
D) buccal mucosa.

Pegged or absent maxillary lateral incisors:

A mother who is a carrier of an X-linked recessive trait has a 50% risk of having a(n):

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

Each of the following statements about chromosomes is true except one. Which one is the exception?

Radicular dentin dysplasia is characterized by teeth with _ crowns and _ roots.

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Cri du chat

The areas of bony radiolucency seen in cherubism:

Murray-Puretic-Drescher syndrome is also known as:

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -The observable appearance of an individual

Which of the following statements about the hereditary opalescent form of dentinogenesis imperfecta is true?

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

__________ is an inherited disorder affecting the gingiva and periodontium, which is characterized by hyperkeratosis of the palms of the hands and soles of the feet.

Which of the following statements is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Nonsex chromosomes that are identical for men and women

Which of the following statements is true of oogenesis?

Hypophosphatasia is characterized by:

Telangiectasias of the oral mucosa for a patient with hereditary hemorrhagic telangiectasia will be especially prominent on the:

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

Pegged or absent maxillary lateral incisors:

A mother who is a carrier of an X-linked recessive trait has a 50% risk of having a(n):

Gingival and periodontal disease has been reported in _____% of individuals with Down syndrome.

A patient with _____ will have a mouth that appears fishlike, with downward sloping of the lip commissures.

Each of the following statements about chromosomes is true except one. Which one is the exception?

Radicular dentin dysplasia is characterized by teeth with _____ crowns and _____ roots.

For autosomal-dominant inheritance, _____ pertains to the degree to which an individual is affected.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Cri du chat

The areas of bony radiolucency seen in cherubism:

Murray-Puretic-Drescher syndrome is also known as:

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -The observable appearance of an individual

Which of the following statements about the hereditary opalescent form of dentinogenesis imperfecta is true?

The _____ type of amelogenesis imperfecta is characterized by tooth enamel that does not develop to a normal thickness because of failure of the ameloblasts to lay down enamel matrix properly.

__________ is an inherited disorder affecting the gingiva and periodontium, which is characterized by hyperkeratosis of the palms of the hands and soles of the feet.

Which of the following statements is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?

A patient with Papillon-Lefèvre syndrome will show a marked gingivoperiodontal inflammatory condition in the primary teeth at about _____ years of age.

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Nonsex chromosomes that are identical for men and women

Which of the following statements is true of oogenesis?

Hypophosphatasia is characterized by:

Telangiectasias of the oral mucosa for a patient with hereditary hemorrhagic telangiectasia will be especially prominent on the:

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

Radicular dentin dysplasia is characterized by teeth with _ crowns and _ roots.