Question 1

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-Set of signs or symptoms occurring together

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome F

Question 2

Which of the following syndromes is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

Accepted Answer

A) Osler-Rendu-Parkes Weber syndrome 
B) Van der Woude syndrome 
C) Gorlin syndrome 
D) Peutz-Jeghers syndrome 
A) Osler-Rendu-Parkes Weber syndrome 
B) Van der Woude syndrome 
C) Gorlin syndrome 
D) Peutz-Jeghers syndrome D

Question 3

During meiosis, when chromosomes that were crossing over do not separate, and both migrate to the same cell, resulting in a germ cell with an extra chromosome, this is referred to as:

Accepted Answer

A) nondisjunction. 
B) chiasmata. 
C) translation. 
D) alleles. 
A) nondisjunction. 
B) chiasmata. 
C) translation. 
D) alleles. A

Question 4

Genetic heterogeneity can cause amelogenesis imperfecta because of its inheritance pattern (X-linked, autosomal recessive, or autosomal dominant).

Accepted Answer

A) Both the statement and reason are correct and related. 
B) Both the statement and reason are correct but not related. 
C) The statement is correct, but the reason is not. 
D) The statement is not correct, but the reason is correct. 
E) Neither the statement nor the reason is correct. 
A) Both the statement and reason are correct and related. 
B) Both the statement and reason are correct but not related. 
C) The statement is correct, but the reason is not. 
D) The statement is not correct, but the reason is correct. 
E) Neither the statement nor the reason is correct.

Question 5

In DNA a sequence of thymine, adenine, and cytosine (TAC) is always matched by:

Accepted Answer

A) adenine, cytosine, and guanine (ACG). 
B) guanine, adenine, and cytosine (GA
C) . 
C) adenine, thymine, and guanine (ATG). 
D) a five-carbon sugar and a phosphate. 
A) adenine, cytosine, and guanine (ACG). 
B) guanine, adenine, and cytosine (GA
C) . 
C) adenine, thymine, and guanine (ATG). 
D) a five-carbon sugar and a phosphate.

Question 6

_________ is a consistent feature of mandibulofacial dysostosis.

Accepted Answer

A) Hypertrichosis 
B) Deafness 
C) Hypertelorism 
D) Kyphoscoliosis 
A) Hypertrichosis 
B) Deafness 
C) Hypertelorism 
D) Kyphoscoliosis

Question 7

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of:

Accepted Answer

A) squamous cell carcinoma. 
B) basal cell carcinoma. 
C) thyroid carcinoma. 
D) osteogenic sarcoma. 
A) squamous cell carcinoma. 
B) basal cell carcinoma. 
C) thyroid carcinoma. 
D) osteogenic sarcoma.

Question 8

Hard, dense, cortical bone on the buccal aspect of the alveolar ridge by tooth number 14 would be termed a:

Accepted Answer

A) radiolucent torus palatinus. 
B) radiopaque torus mandibularis. 
C) radiopaque exostosis. 
D) radiolucent exostosis. 
A) radiolucent torus palatinus. 
B) radiopaque torus mandibularis. 
C) radiopaque exostosis. 
D) radiolucent exostosis.

Question 9

The majority of patients with Turner syndrome have a _____ phenotype and _____ chromosomes.

Accepted Answer

A) male; 47 
B) female; 46 
C) female; 45 
D) male; 44 
A) male; 47 
B) female; 46 
C) female; 45 
D) male; 44

Question 10

Neurofibromatosis of von Recklinghausen is characterized by:

Accepted Answer

A) multiple neurofibromas appearing as macules of various sizes. 
B) inevitable malignant transformation. 
C) oral involvement in about 90% of patients. 
D) café au lait pigmentation of the skin in 90% of patients. 
A) multiple neurofibromas appearing as macules of various sizes. 
B) inevitable malignant transformation. 
C) oral involvement in about 90% of patients. 
D) café au lait pigmentation of the skin in 90% of patients.

Question 11

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

Accepted Answer

A) telophase 
B) metaphase 
C) prophase 
D) anaphase 
A) telophase 
B) metaphase 
C) prophase 
D) anaphase

Question 12

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are:

Accepted Answer

A) central giant cell granulomas. 
B) peripheral giant cell granulomas. 
C) odontogenic keratocysts. 
D) calcifying epithelial odontogenic tumors. 
A) central giant cell granulomas. 
B) peripheral giant cell granulomas. 
C) odontogenic keratocysts. 
D) calcifying epithelial odontogenic tumors.

Question 13

A karyotype containing XXXY indicates _____ syndrome.

Accepted Answer

A) Down 
B) Klinefelter 
C) Turner 
D) cri du chat 
A) Down 
B) Klinefelter 
C) Turner 
D) cri du chat

Question 14

Which of the following syndromes is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Accepted Answer

A) Osler-Rendu-Parkes Weber syndrome 
B) Ellis-van Creveld syndrome 
C) Gorlin syndrome 
D) Peutz-Jeghers syndrome 
A) Osler-Rendu-Parkes Weber syndrome 
B) Ellis-van Creveld syndrome 
C) Gorlin syndrome 
D) Peutz-Jeghers syndrome

Question 15

Which of the following syndromes is characterized by intestinal polyps, which become malignant at age 30 and after?

Accepted Answer

A) Osteogenesis imperfecta 
B) Nevoid basal cell carcinoma syndrome 
C) Mandibulofacial dysostosis 
D) Gardner syndrome 
A) Osteogenesis imperfecta 
B) Nevoid basal cell carcinoma syndrome 
C) Mandibulofacial dysostosis 
D) Gardner syndrome

Question 16

If both loci for blood are AO, the

Accepted Answer

A) person is said to have blood group O. 
B) person is said to have blood group A. 
C) person would be homozygous. 
D) characteristic is recessive. 
A) person is said to have blood group O. 
B) person is said to have blood group A. 
C) person would be homozygous. 
D) characteristic is recessive.

Question 17

Blood group _____ is an example of gene codominance.

Accepted Answer

A) O 
B) A 
C) B 
D) AB 
A) O 
B) A 
C) B 
D) AB

Question 18

Intestinal polyps seen with Peutz-Jeghers syndrome are:

Accepted Answer

A) associated with inevitable malignant transformation into adenocarcinomas. 
B) hamartomas. 
C) caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D) associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla. 
A) associated with inevitable malignant transformation into adenocarcinomas. 
B) hamartomas. 
C) caused by the adenomatous polyposis coli (AP
C)  gene located on the long arm of chromosome 5. 
D) associated with osteomas in various bones, especially the frontal bones, mandible, and maxilla.

Question 19

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and:

Accepted Answer

A) telangiectases. 
B) pheochromocytoma. 
C) gastrointestinal polyposis. 
D) blue sclera. 
A) telangiectases. 
B) pheochromocytoma. 
C) gastrointestinal polyposis. 
D) blue sclera.

Question 20

Which of the following statements is true concerning hemophilia A?

Accepted Answer

A) It is inherited as an X-linked dominant condition. 
B) It is inherited as a Y-linked recessive condition. 
C) All X chromosomes are abnormal in the female carrier. 
D) Female carriers tend to bleed more than usual after extraction of teeth or scaling and curettage. 
A) It is inherited as an X-linked dominant condition. 
B) It is inherited as a Y-linked recessive condition. 
C) All X chromosomes are abnormal in the female carrier. 
D) Female carriers tend to bleed more than usual after extraction of teeth or scaling and curettage.

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Set of signs or symptoms occurring together

Which of the following syndromes is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

During meiosis, when chromosomes that were crossing over do not separate, and both migrate to the same cell, resulting in a germ cell with an extra chromosome, this is referred to as:

Genetic heterogeneity can cause amelogenesis imperfecta because of its inheritance pattern (X-linked, autosomal recessive, or autosomal dominant).

In DNA a sequence of thymine, adenine, and cytosine (TAC) is always matched by:

_________ is a consistent feature of mandibulofacial dysostosis.

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of:

Hard, dense, cortical bone on the buccal aspect of the alveolar ridge by tooth number 14 would be termed a:

The majority of patients with Turner syndrome have a _ phenotype and _ chromosomes.

Neurofibromatosis of von Recklinghausen is characterized by:

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are:

A karyotype containing XXXY indicates _____ syndrome.

Which of the following syndromes is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Which of the following syndromes is characterized by intestinal polyps, which become malignant at age 30 and after?

If both loci for blood are AO, the

Blood group _____ is an example of gene codominance.

Intestinal polyps seen with Peutz-Jeghers syndrome are:

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and:

Which of the following statements is true concerning hemophilia A?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Set of signs or symptoms occurring together

Which of the following syndromes is characterized by multiple melanotic macular pigmentations of the skin and mucosa, which are associated with gastrointestinal polyposis?

During meiosis, when chromosomes that were crossing over do not separate, and both migrate to the same cell, resulting in a germ cell with an extra chromosome, this is referred to as:

Genetic heterogeneity can cause amelogenesis imperfecta because of its inheritance pattern (X-linked, autosomal recessive, or autosomal dominant).

In DNA a sequence of thymine, adenine, and cytosine (TAC) is always matched by:

_________ is a consistent feature of mandibulofacial dysostosis.

Early diagnosis of pheochromocytoma is imperative because of the high malignant potential of:

Hard, dense, cortical bone on the buccal aspect of the alveolar ridge by tooth number 14 would be termed a:

The majority of patients with Turner syndrome have a _____ phenotype and _____ chromosomes.

Neurofibromatosis of von Recklinghausen is characterized by:

Chromosomes line up at the equatorial plate during the _____ stage of mitosis.

Oral manifestations of nevoid basal cell carcinoma syndrome consist of multiple cysts of the jaws that are:

A karyotype containing XXXY indicates _____ syndrome.

Which of the following syndromes is characterized by a fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Which of the following syndromes is characterized by intestinal polyps, which become malignant at age 30 and after?

If both loci for blood are AO, the

Blood group _____ is an example of gene codominance.

Intestinal polyps seen with Peutz-Jeghers syndrome are:

Multiple mucosal neuroma syndrome includes multiple mucosal neuromas, medullary carcinoma of the thyroid gland, and:

Which of the following statements is true concerning hemophilia A?

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

The majority of patients with Turner syndrome have a _ phenotype and _ chromosomes.