Question 1

A man's X chromosome is transmitted to _____ of his daughters and _____ of his sons.

Accepted Answer

A) none; none 
B) none; all 
C) all; none 
D) all; all 
A) none; none 
B) none; all 
C) all; none 
D) all; all

Question 2

For autosomal-dominant inheritance:

Accepted Answer

A) males will be affected more often than females. 
B) the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C) all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D) an individual can carry a gene with a dominant effect without presenting any clinical manifestations. 
A) males will be affected more often than females. 
B) the risk of having an affected offspring is 25% when a person has a gene for the condition. 
C) all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance. 
D) an individual can carry a gene with a dominant effect without presenting any clinical manifestations.

Question 3

Which is true about making a karyotype?

Accepted Answer

A) Arginine may be used to arrest the mitosis of leukocytes at metaphase. 
B) Colchicine may be used to arrest the mitosis of leukocytes at metaphase. 
C) Colchicine may be used to arrest the mitosis of red blood cells at anaphase. 
D) It is used to evaluate molecular abnormalities in chromosomes. 
A) Arginine may be used to arrest the mitosis of leukocytes at metaphase. 
B) Colchicine may be used to arrest the mitosis of leukocytes at metaphase. 
C) Colchicine may be used to arrest the mitosis of red blood cells at anaphase. 
D) It is used to evaluate molecular abnormalities in chromosomes.

Question 4

After metaphase of the first meiotic division:

Accepted Answer

A) the chromosomes split at the centromere and separate from one another. 
B) the chromosomes do not split at the centromere but separate from one another. 
C) each member of the pair migrates to one of the new cells, each of which contains 46 chromosomes but twice the final amount of DNA. 
D) each member of the pair migrates to one of the new cells, each of which contains 23 chromosomes but half the final amount of DNA. 
A) the chromosomes split at the centromere and separate from one another. 
B) the chromosomes do not split at the centromere but separate from one another. 
C) each member of the pair migrates to one of the new cells, each of which contains 46 chromosomes but twice the final amount of DNA. 
D) each member of the pair migrates to one of the new cells, each of which contains 23 chromosomes but half the final amount of DNA.

Question 5

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Accepted Answer

A) alteration in the structure 
B) abnormal rearrangement 
C) alteration in the number 
D) duplication 
A) alteration in the structure 
B) abnormal rearrangement 
C) alteration in the number 
D) duplication

Question 6

Which of the following disorders affecting the jaw bones and facies is characterized by fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

Accepted Answer

A) Gardner syndrome 
B) Mandibulofacial dysostosis 
C) Ellis-van Creveld syndrome 
D) Cherubism 
A) Gardner syndrome 
B) Mandibulofacial dysostosis 
C) Ellis-van Creveld syndrome 
D) Cherubism

Question 7

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-Permanent change in the arrangement of genetic material

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 8

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-Spermatozoon or ovum

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

Question 9

The basic defect found with radicular dentin dysplasia seems to lie in the:

Accepted Answer

A) stellate reticulum. 
B) epithelial root sheath. 
C) stratum intermedium. 
D) dental papilla. 
A) stellate reticulum. 
B) epithelial root sheath. 
C) stratum intermedium. 
D) dental papilla.

Question 10

A codon in DNA is formed by a sequence of _____ bases.

Accepted Answer

A) two 
B) three 
C) four 
D) six 
A) two 
B) three 
C) four 
D) six

Question 11

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.

-Turner

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 12

Characteristic radiographic oral findings of hypophosphatemic vitamin D-resistant rickets include:

Accepted Answer

A) obliterated pulp chambers. 
B) large pulp chambers with very long pulp horns. 
C) normal pulp chambers with nonexistent roots. 
D) large pulp chambers with nonexistent pulp horns. 
A) obliterated pulp chambers. 
B) large pulp chambers with very long pulp horns. 
C) normal pulp chambers with nonexistent roots. 
D) large pulp chambers with nonexistent pulp horns.

Question 13

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided.

-Klinefelter

Accepted Answer

A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome 
A) Characterized by multiple abnormalities in various organs 
B) Down syndrome as a result of nondisjunction 
C) Nondisjunction of the X chromosome in the paternal gamete 
D) Deletion on the short arm of chromosome 5 
E) Fertilized ovum has two X chromosomes plus a Y chromosome

Question 14

Features of second meiosis include:

Accepted Answer

A) a replication of DNA before initiation. 
B) essentially a mitotic division in which each chromosome splits longitudinally. 
C) formation of four cells from the parent cell. 
D) the formation of 2n DNA. 
A) a replication of DNA before initiation. 
B) essentially a mitotic division in which each chromosome splits longitudinally. 
C) formation of four cells from the parent cell. 
D) the formation of 2n DNA.

Question 15

Primitive germ cells have _____ chromosomes and are called _____.

Accepted Answer

A) 23; diploid 
B) 46; haploid 
C) 23; haploid 
D) 46; diploid 
A) 23; diploid 
B) 46; haploid 
C) 23; haploid 
D) 46; diploid

Question 16

Each of the following statements is true regarding focal palmoplantar and gingival hyperkeratosis except one. Which one is the exception?

Accepted Answer

A) Marked hyperkeratosis follows the normal contour of the gingiva. 
B) The free gingiva is highly affected with hyperkeratosis. 
C) Oral changes start in childhood and increase with age. 
D) Oral hyperkeratinization is bandlike and a few millimeters in width. 
A) Marked hyperkeratosis follows the normal contour of the gingiva. 
B) The free gingiva is highly affected with hyperkeratosis. 
C) Oral changes start in childhood and increase with age. 
D) Oral hyperkeratinization is bandlike and a few millimeters in width.

Question 17

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in:

Accepted Answer

A) lack of otic ossicles. 
B) unilateral or bilateral aplasia or hypoplasia of clavicles. 
C) overgrowth of cortical bone in the midline of the palate. 
D) abnormally formed bones that fracture easily. 
A) lack of otic ossicles. 
B) unilateral or bilateral aplasia or hypoplasia of clavicles. 
C) overgrowth of cortical bone in the midline of the palate. 
D) abnormally formed bones that fracture easily.

Question 18

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

Accepted Answer

A) I: hypoplastic 
B) II: hypocalcified 
C) III: hypomaturation 
D) IV: hypoplastic-hypomaturation 
A) I: hypoplastic 
B) II: hypocalcified 
C) III: hypomaturation 
D) IV: hypoplastic-hypomaturation

Question 19

Which of the following statements is true regarding management of patients with cyclic neutropenia?

Accepted Answer

A) Preventive antibiotic therapy is instituted to protect against secondary opportunistic infections. 
B) Treatment should be done when the circulating neutrophil count is low to reduce the risk of complications such as gingival hemorrhage and secondary infection. 
C) Dental hygiene care increases the risk of opportunistic infections in patients with cyclic neutropenia. 
D) Patients are treated periodically with vitamin D to reduce symptoms. 
A) Preventive antibiotic therapy is instituted to protect against secondary opportunistic infections. 
B) Treatment should be done when the circulating neutrophil count is low to reduce the risk of complications such as gingival hemorrhage and secondary infection. 
C) Dental hygiene care increases the risk of opportunistic infections in patients with cyclic neutropenia. 
D) Patients are treated periodically with vitamin D to reduce symptoms.

Question 20

MATCHING
For each genetic definition below, select the corresponding genetic term from the list provided.

-Position occupied by a gene on a chromosome

Accepted Answer

A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome 
A) Autosomes 
B) Gamete 
C) Locus 
D) Mutation 
E) Phenotype
F)Syndrome

A man's X chromosome is transmitted to _ of his daughters and _ of his sons.

For autosomal-dominant inheritance:

Which is true about making a karyotype?

After metaphase of the first meiotic division:

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Which of the following disorders affecting the jaw bones and facies is characterized by fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Permanent change in the arrangement of genetic material

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Spermatozoon or ovum

The basic defect found with radicular dentin dysplasia seems to lie in the:

A codon in DNA is formed by a sequence of _____ bases.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Turner

Characteristic radiographic oral findings of hypophosphatemic vitamin D-resistant rickets include:

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Klinefelter

Features of second meiosis include:

Primitive germ cells have _ chromosomes and are called _.

Each of the following statements is true regarding focal palmoplantar and gingival hyperkeratosis except one. Which one is the exception?

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in:

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

Which of the following statements is true regarding management of patients with cyclic neutropenia?

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

Exam 6: Genetics

A man's X chromosome is transmitted to _____ of his daughters and _____ of his sons.

For autosomal-dominant inheritance:

Which is true about making a karyotype?

After metaphase of the first meiotic division:

Euploid, polyploid, and aneuploid are all terms relating to a(n) _____ of chromosomes.

Which of the following disorders affecting the jaw bones and facies is characterized by fusion of the anterior portion of the maxillary gingiva to the upper lip from canine to canine?

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Permanent change in the arrangement of genetic material

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Spermatozoon or ovum

The basic defect found with radicular dentin dysplasia seems to lie in the:

A codon in DNA is formed by a sequence of _____ bases.

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Turner

Characteristic radiographic oral findings of hypophosphatemic vitamin D-resistant rickets include:

For each clinical syndrome below, select the corresponding chromosomal abnormality from the list provided. -Klinefelter

Features of second meiosis include:

Primitive germ cells have _____ chromosomes and are called _____.

Each of the following statements is true regarding focal palmoplantar and gingival hyperkeratosis except one. Which one is the exception?

The basic defect responsible for osteogenesis imperfecta is produced by various mutations affecting the genes that encode type I collagen, resulting in:

Snow-capped amelogenesis imperfecta is a variation of type _____ amelogenesis imperfecta.

Which of the following statements is true regarding management of patients with cyclic neutropenia?

MATCHING For each genetic definition below, select the corresponding genetic term from the list provided. -Position occupied by a gene on a chromosome

Introduction to Preliminary Diagnosis of Oral Lesions

Inflammation and Repair

Immunity and Immunologic Oral Lesions

Infectious Diseases

Developmental Disorders

Neoplasia

Nonneoplastic Diseases of Bone

Oral Manifestations of Systemic Diseases

Diseases Affecting the Temporomandibular Joint

Filters

A man's X chromosome is transmitted to _ of his daughters and _ of his sons.

Primitive germ cells have _ chromosomes and are called _.