Question 1

Which of the following substrates requires the coenzyme thiamine pyrophosphate (TPP)for catalyzing its decarboxylation reaction?

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 2

Which of the following statements is/are true about 5-fluorouracil,

Accepted Answer

A) It is an anticancer drug. 
B) It inhibits the enzyme thymidylate synthase. 
C) It is an example of a mechanism-based inhibitor. 
D) It is an example of a suicide inhibitor. 
E) all of the above 
A) It is an anticancer drug. 
B) It inhibits the enzyme thymidylate synthase. 
C) It is an example of a mechanism-based inhibitor. 
D) It is an example of a suicide inhibitor. 
E) all of the above

Question 3

Which of the following is/are coenzyme(s)formed from the vitamin niacin?

Accepted Answer

A) NAD+ 
B) NADP+ 
C) NADH 
D) NADPH 
E) all of the above 
A) NAD+ 
B) NADP+ 
C) NADH 
D) NADPH 
E) all of the above

Question 4

In a process known as oxidative phosphorylation, every NADH that is formed in carrying out oxidation reactions in the early stages of catabolism is converted into ________.

Accepted Answer

A) three ATPs 
B) two ATPs 
C) four FADHs 
D) six acetyl-CoAs 
E) none of the above 
A) three ATPs 
B) two ATPs 
C) four FADHs 
D) six acetyl-CoAs 
E) none of the above

Question 5

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 6

Give the purpose of TPP as a coenzyme.

Accepted Answer

A) a coenzyme that catalyzes the transfer of a one-carbon fragment 
B) a coenzyme that catalyzes the carboxylation of the alpha carbon 
C) a coenzyme that catalyzes the transfer of a three-carbon fragment 
D) a coenzyme that catalyzes the carboxylation of the beta carbon 
E) a coenzyme that catalyzes the transfer of a two-carbon fragment 
A) a coenzyme that catalyzes the transfer of a one-carbon fragment 
B) a coenzyme that catalyzes the carboxylation of the alpha carbon 
C) a coenzyme that catalyzes the transfer of a three-carbon fragment 
D) a coenzyme that catalyzes the carboxylation of the beta carbon 
E) a coenzyme that catalyzes the transfer of a two-carbon fragment

Question 7

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 8

List the four stages of catabolism and briefly explain the significance of each.

Accepted Answer

The first stage of catabolism is called

Question 9

Which of the following is not a lipid-soluble vitamin?

Accepted Answer

A) vitamin A 
B) vitamin D 
C) vitamin E 
D) vitamin C 
E) vitamin K 
A) vitamin A 
B) vitamin D 
C) vitamin E 
D) vitamin C 
E) vitamin K

Question 10

Which of the following is/are the coenzyme(s)formed from the vitamin thiamine (B1)?

Accepted Answer

A) TPP 
B) CoASH 
C) PLP 
D) THF 
E) FAD 
A) TPP 
B) CoASH 
C) PLP 
D) THF 
E) FAD

Question 11

What are catabolic and anabolic reactions?

Accepted Answer

Catabolic reactions are reactions where

Question 12

5-Fluorouracil is an anticancer drug that inhibits what essential enzyme?

Accepted Answer

Thymidylat

Question 13

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 14

What does the term "Pyridoxal" stand for?

Accepted Answer

A) Pyridine aldehyde 
B) Pyrrol oxyaldehyde 
C) Pyrrolidine oxyaldehyde 
D) Peroxy aldehyde 
E) Pyrimidoxy aldehyde 
A) Pyridine aldehyde 
B) Pyrrol oxyaldehyde 
C) Pyrrolidine oxyaldehyde 
D) Peroxy aldehyde 
E) Pyrimidoxy aldehyde

Question 15

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 16

Which of the following reactions of amino acids is not catalyzed by PLP-requiring enzymes?

Accepted Answer

A) decarboxylation 
B) transamination 
C) α, β-elimination 
D) α-keto esterification 
E) Cα-Cβ bond cleavage 
A) decarboxylation 
B) transamination 
C) α, β-elimination 
D) α-keto esterification 
E) Cα-Cβ bond cleavage

Question 17

Which of the following is the sequence of steps followed by biotin-dependent enzymes, as listed below? I. Transfer of the carboxyl group from carboxybiotin to the substrate
II) Activation of bicarbonate by ATP
III) Formation of carboxybiotin

Accepted Answer

A) I, II, III 
B) I, III, II 
C) II, I, III 
D) II, III, I 
E) III, II, I 
A) I, II, III 
B) I, III, II 
C) II, I, III 
D) II, III, I 
E) III, II, I

Question 18

Identify the compound below.

Accepted Answer

A) pyridoxine 
B) ascorbic acid 
C) thiamine 
D) lipoate 
E) niacin 
A) pyridoxine 
B) ascorbic acid 
C) thiamine 
D) lipoate 
E) niacin

Question 19

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 20

Explain what is meant by a nucleotide and give an example.

Accepted Answer

A nucleotide is composed of a heterocycl

Exam 24: The Organic Mechanisms of the Coenzymes

Which of the following substrates requires the coenzyme thiamine pyrophosphate (TPP)for catalyzing its decarboxylation reaction?

Which of the following statements is/are true about 5-fluorouracil,

Which of the following is/are coenzyme(s)formed from the vitamin niacin?

In a process known as oxidative phosphorylation, every NADH that is formed in carrying out oxidation reactions in the early stages of catabolism is converted into ________.

Give the product for the following reaction.

Give the purpose of TPP as a coenzyme.

Give the product for the following reaction.

List the four stages of catabolism and briefly explain the significance of each.

Which of the following is not a lipid-soluble vitamin?

Which of the following is/are the coenzyme(s)formed from the vitamin thiamine (B1)?

What are catabolic and anabolic reactions?

5-Fluorouracil is an anticancer drug that inhibits what essential enzyme?

Give the product for the following reaction.

What does the term "Pyridoxal" stand for?

Give the product for the following reaction.

Which of the following reactions of amino acids is not catalyzed by PLP-requiring enzymes?

Which of the following is the sequence of steps followed by biotin-dependent enzymes, as listed below? I. Transfer of the carboxyl group from carboxybiotin to the substrate II) Activation of bicarbonate by ATP III) Formation of carboxybiotin

Identify the compound below.

Give the product for the following reaction.

Explain what is meant by a nucleotide and give an example.

Remembering General Chemistry: Electronic Structure and Bonding

Acids and Bases: Central to Understanding Organic Chemistry

An Introduction to Organic Compounds

Isomers: the Arrangement of Atoms in Space

Alkenes Thermodynamics and Kinetics

Reactions of Alkenes

Reactions of Alkynes Introduction to Multistep Synthesis

Electron Delocalization, Resonance, and Aromaticity More About Molecular Orbital Theory

Substitution Reactions of Alkyl Halides

Elimination Reactions of Alkyl Halides Competition Between Substitution and Elimination

Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds

Organometallic Compounds

Reactions of Alkanes, Radicals

Mass Spectrometry, Infrared Spectroscopy, and Uvvis Spectroscopy

Nmr Spectroscopy

Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

Reactions of Aldehydes and Ketones

Reactions at the Alpha Carbon of Carbonyl Compounds

Reactions of Benzene and Substituted Benzenes

More About Amines Heterocylic Compounds

Carbohydrates

Amino Acids, Peptides, and Proteins

Catalysis

The Chemistry of Metabolism

Nucleosides, Nucleotides, and Nucleic Acids

Synthetic Polymers

Pericyclic Reactions

Filters

Which of the following is/are the coenzyme(s)formed from the vitamin thiamine (B₁)?