Question 1

The most efficient method of preventing graft-versus-host disease (GVHD)is:

Accepted Answer

A)  irradiating the patient before transfusion. 
B)  irradiating the blood components before transfusion. 
C)  administering antibiotics before transfusion. 
D)  administering steroids after transfusion. 
A)  irradiating the patient before transfusion. 
B)  irradiating the blood components before transfusion. 
C)  administering antibiotics before transfusion. 
D)  administering steroids after transfusion.

Question 2

Patients who are severely immunocompromised or immunosuppressed are unable to reject donor cells.

Accepted Answer

A) True 
 B)False

Question 3

MATCHING
Match the terms with the appropriate definition.

-Allograft

Accepted Answer

A) Graft between individuals of different species (e.g. ,pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g. ,skin,hair,bone) 
C) Graft between genetically different recipient and donor of the same species;grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g. ,kidney transplant between monozygous twins) 
A) Graft between individuals of different species (e.g. ,pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g. ,skin,hair,bone) 
C) Graft between genetically different recipient and donor of the same species;grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g. ,kidney transplant between monozygous twins)

Question 4

MATCHING
Match the terms with the appropriate definition.

-Autograft

Accepted Answer

A) Graft between individuals of different species (e.g. ,pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g. ,skin,hair,bone) 
C) Graft between genetically different recipient and donor of the same species;grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g. ,kidney transplant between monozygous twins) 
A) Graft between individuals of different species (e.g. ,pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g. ,skin,hair,bone) 
C) Graft between genetically different recipient and donor of the same species;grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g. ,kidney transplant between monozygous twins)

Question 5

Match the groups receiving therapy with their risk of graft-versus-host disease (GVHD).

-Patients receiving total-body radiation or immunosuppressive therapy for disorders such as lymphoma and acute leukemia

Accepted Answer

A) High-risk patients 
B) Intermediate-risk patients 
C) Low-risk patients 
A) High-risk patients 
B) Intermediate-risk patients 
C) Low-risk patients

Question 6

If an organ is rejected within 1 week after transplant (acute rejection),the predominant mechanism is ______-mediated.

Accepted Answer

A)  T lymphocyte 
B)  B lymphocyte 
C)  macrophage 
D)  segmented neutrophil 
A)  T lymphocyte 
B)  B lymphocyte 
C)  macrophage 
D)  segmented neutrophil

Question 7

The mainstay of immunosuppression therapy in transplantation is:

Accepted Answer

A)  azathioprine. 
B)  corticosteroids. 
C)  cyclosporine. 
D)  antilymphocyte globulin. 
A)  azathioprine. 
B)  corticosteroids. 
C)  cyclosporine. 
D)  antilymphocyte globulin.

Question 8

Rejection of a graft displays the key feature(s)of adaptive immunity,which is:

Accepted Answer

A)  memory 
B)  specificity 
C)  antibody formation 
D)  both a and b 
A)  memory 
B)  specificity 
C)  antibody formation 
D)  both a and b

Exam 31: Solid Organ Transplantation

The most efficient method of preventing graft-versus-host disease (GVHD)is:

Patients who are severely immunocompromised or immunosuppressed are unable to reject donor cells.

MATCHING Match the terms with the appropriate definition. -Allograft

MATCHING Match the terms with the appropriate definition. -Autograft

Match the groups receiving therapy with their risk of graft-versus-host disease (GVHD). -Patients receiving total-body radiation or immunosuppressive therapy for disorders such as lymphoma and acute leukemia

If an organ is rejected within 1 week after transplant (acute rejection),the predominant mechanism is ______-mediated.

The mainstay of immunosuppression therapy in transplantation is:

Rejection of a graft displays the key feature(s)of adaptive immunity,which is:

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Immunoproliferative Disorders

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Bone Marrow Transplantation

Tumor Immunology

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